Thyroid hormones; plasma level in critical ill patients need prolonged mechanical ventilation

Secondary bacterial infections occurred in 13.9% (5 of 36) of critical ill patients with coronavirus disease 2019. All 5 patients had been admitted to intensive care unit and received mechanical ventilation before developing bacterial infection. Active surveillance of culture should be performed for critically ill patients. Prevention of nosocomial infection should to be taken seriously.

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The effect of early mobilization for critical ill patients requiring mechanical ventilation: a systematic review and meta-analysis

Journal of Emergency and Critical Care Medicine ◽

10.21037/jeccm.2018.01.04 ◽

2018 ◽

Vol 2 ◽

pp. 9-9 ◽

Cited By ~ 3

Author(s):

Gensheng Zhang ◽

Kai Zhang ◽

Wei Cui ◽

Yucai Hong ◽

Zhongheng Zhang

Keyword(s):

Systematic Review ◽

Mechanical Ventilation ◽

Meta Analysis ◽

Early Mobilization ◽

Critical Ill Patients ◽

Critical Ill

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Acute Poisoning with Methidathion: A Case

Human & Experimental Toxicology ◽

10.1177/096032719000900610 ◽

1990 ◽

Vol 9 (6) ◽

pp. 415-419 ◽

Cited By ~ 8

Author(s):

R. Zoppellari ◽

L. Targa ◽

P. Tonini ◽

R. Zatelli

Keyword(s):

Mechanical Ventilation ◽

Plasma Level ◽

Gastric Juice ◽

Clinical Course ◽

Prolonged Mechanical Ventilation ◽

Gastric Lavage ◽

Acute Poisoning ◽

Neuropathy Target Esterase ◽

Phosphorus Ester

An acute poisoning in a 50-year-old man who ingested approximately 6.2 g of the phosphorus ester methidathion is described. The patient was treated with three haemoperfusions 23, 44 and 115 h after ingestion, with continuous gastric lavage, atropine and pralidoxime administration and with prolonged mechanical ventilation. Haemoperfusion was an ineffective epuration technique since it removed only 0.22% of the ingested methidathion. The clinical course wavered because of a probable redistribution of phosphorus ester from fat to blood. A plasma level higher than 100 μg l-1 was associated with the most serious phases. Methidathion was present in the plasma until the sixth day, in the urine until the seventh and in the gastric juice until the eighth. Its absence in the fat biopsy made on the tenth day was an aid to therapy. The phosphorus ester did not inhibit lymphocyte neuropathy target esterase (NTE), neither did it induce development of delayed polyneuropathy.

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ENDURANCE TRAINING OF THE RESPIRATORY MUSCLES IN CRITICAL ILL PATIENTS ON MECHANICAL VENTILATION

International Journal of Physiotherapy ◽

10.15621/ijphy/2019/v6i6/190219 ◽

2019 ◽

Vol 6 (6) ◽

Author(s):

MADS BORUP ◽

ANNA HESBY ◽

KARINA POULSEN ◽

ANNE HØYER ◽

MADS KRISTIAN HOLTEN ◽

...

Keyword(s):

Mechanical Ventilation ◽

Endurance Training ◽

Respiratory Muscles ◽

Critical Ill Patients ◽

Critical Ill

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The effect of percutaneous and surgical tracheotomy on thyroid hormones levels

Health & Research Journal ◽

10.12681/healthresj.26809 ◽

2021 ◽

Vol 7 (2) ◽

pp. 85

Author(s):

Christina Sampani ◽

Ioannis Kalemikerakis ◽

Antonia Kalogianni ◽

Dimitrios Papageorgiou

Keyword(s):

Intensive Care Unit ◽

Mechanical Ventilation ◽

Intensive Care ◽

Thyroid Hormones ◽

Prolonged Mechanical Ventilation ◽

Percutaneous Tracheostomy ◽

Thyroid Stimulating Hormone ◽

The Difference ◽

The Impact ◽

Surgical Group

Background: The need for prolonged mechanical ventilation is one of the most serious cases of a disease in patients in intensive care units. Tracheostomy is often considered as a solution when mechanical ventilation is expected to be used for prolonged periods or for improvement of the respiratory state as this approach provides protection of the airways, facilitates access to remove secretions, improves patient convenience and promotes the development of care inside and outside the Intensive Care Unit (ICU).Aim: The aim of the present study was to evaluate the impact of surgical and percutaneous tracheotomy on thyroid hormones and to compare them.Material & Methods: This is a non-randomized clinical trial. The studied sample consisted of 87 patients from the Intensive Care Unit of a General Hospital of Athens who underwent percutaneous or surgical tracheotomy.Results: Thyroid-stimulating hormone levels were increased in surgical group compared to percutaneous group at 2 hours post procedure but the difference was not found statistically significant. The rise in post-operative levels of fT3 compared to preoperative was found statistically significant for surgical tracheostomy group. Elevated fT4 levels were found in both groups.Conclusions: The effect of surgical versus percutaneous tracheostomy on thyroid hormone was analyzed and it was found that both procedures may affect the level of thyroid hormones, being significant in the surgical group.

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Clinical characteristics and current treatment of critically ill patients with COVID-19 outside Wuhan, China: a multicenter, retrospective, observational study

10.21203/rs.3.rs-17390/v1 ◽

2020 ◽

Cited By ~ 1

Author(s):

Yuhong Chen ◽

Kun Zhang ◽

Guijun Zhu ◽

Lixia Liu ◽

Xixin Yan ◽

...

Keyword(s):

Mechanical Ventilation ◽

Clinical Characteristics ◽

Invasive Mechanical Ventilation ◽

Fluid Management ◽

Hebei Province ◽

Familial Cluster ◽

Chinese Drugs ◽

Critical Ill Patients ◽

Critical Type ◽

Critical Ill

Abstract Background: A novel coronavirus disease 2019 (COVID-19) occurred in Wuhan and rapidly spread elsewhere. The clinical characteristics and treatment of critical ill patients outside Wuhan remain unknown. We aimed to describe the epidemiology and treatment of critical ill patients with COVID-19 in Hebei province.Methods: All patients were from designated hospitals of Hebei province and fit the criteria. We collected the clinical data, laboratory examinations and treatment of all participants.Results: By 14 February 2020, 37 critical ill patients were included. The mean age of the patients was 58.73 (SD 13.76) years, 21 (56.80%) patients were men, 18 (48.60%) were familial cluster, 26 (70.30%) patients had chronic illness. The patients with critical type had a longer period of confirmation time, more severe inflammation and lung injury, a lower lymphocyte percentage. All patients were treated with antiviral agents, 33 (89.20%) with antibacterial agents, 35 (95.60%) patients with methylprednisolone and traditional Chinese drugs. Nine (60.00%) patients with critical type were treated with invasive mechanical ventilation, 9 (60.00%) of those with complications. The patients with critical type received more fluid and more diuretics.Conclusion: Patients with underlying disease and the confirmation time> 10 days were more likely to develop to critical type. The critical type patients had higher risk of infection, respiratory depression, circulatory collapse, and complications. The strategy of lung-protective mechanical ventilation and restrictive fluid management should be strictly followed.

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