The occasional penicillin allergy test

2022 ◽  
Vol 27 (1) ◽  
pp. 29
Author(s):  
Peter Hutten-Czapski
Keyword(s):  
Penicillin Allergy ◽  
Allergy Test

scholarly journals 30. Implementation of the PEN-FAST Penicillin Allergy Screening Tool in the Emergency Department During Medication Reconciliation

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S137-S138
Author(s):  
Satwinder Sony Kaur ◽  
David T Adams ◽  
Brittany Parker
Keyword(s):  
Emergency Department ◽  
Screening Tool ◽  
Healthcare Providers ◽  
Low Risk ◽  
Penicillin Allergy ◽  
Secondary Outcome ◽  
Beta Lactam ◽  
Decision Tool ◽  
Allergy Test ◽  
Risk Patients

Abstract Background The purpose of this study is to implement the PEN-FAST Penicillin Allergy Screening Tool in the emergency department to identify low risk patients with inappropriate penicillin-related allergies to transition them to a beta-lactam. Newly published, validated, penicillin allergy clinician decision tool (PEN-FAST) allows healthcare providers to identify low risk penicillin allergies with a negative predictive value of 96%. This quick, five question clinical decision tool allows healthcare providers and antimicrobial stewardship programs to identify patients who would also test negative if a formal penicillin allergy test was performed, making the process to confidently identify inappropriately labeled penicillin-related allergies more efficient. Methods During routine medication reconciliations, pharmacists will identify patients who have a documented penicillin-related allergy in the EMR and use the PEN-FAST screening tool. Patients meeting inclusion criteria will have their penicillin-related allergy updated in the EMR based upon their assessed risk of very low, low, moderate, or high. The primary outcomes for this study are the percentage of patients screened that were classified as “very low and low risk” and percentage penicillin-related allergies updated. The secondary outcomes are the percentage of patients that required antibiotic therapy (post-allergy update) that were transitioned to a beta-lactam, inpatient broad-spectrum antibiotic usage before and after allergy update, and time spent interviewing each patient. Results A total of 59 patients were interviewed using the PEN-FAST Tool. The results for the primary outcomes indicate 92% (n=54) of patient allergies updated in the EMR, 24% (n=13) of patients classified as “very low risk” and 34% (n=18) of patients classified as “low risk”. Results for the secondary outcome showed out of the 36 patients that were on non-beta lactams during allergy update, 72% (n=26) of those patients were transitioned to a beta-lactam. The average time to complete the PEN-FAST Tool was 4.2 minutes. Conclusion The results of this study support the use of the PEN-FAST Tool in efficiently updating patient’s allergies in the EMR and identifying low risk patients who may be eligible for beta-lactam therapy. Disclosures All Authors: No reported disclosures

Allergy test outcomes in patients self-reported as having penicillin allergy

2016 ◽  
Vol 117 (3) ◽  
pp. 273-279 ◽  
Author(s):  
Juan Meng ◽  
David Thursfield ◽  
Joanna J. Lukawska
Keyword(s):  
Penicillin Allergy ◽  
Allergy Test ◽  
Test Outcomes

Resources Assessment for Penicillin Allergy Testing Performed by Pharmacists at the Patient’s Bedside

2021 ◽  
pp. 106002802110024
Author(s):  
Sophie Gaudreau ◽  
Geneviève Bourque ◽  
Kevin Côté ◽  
Clément Nutu ◽  
Marie-France Beauchesne ◽  
...  
Keyword(s):  
Adverse Effects ◽  
Antibiotic Therapy ◽  
Provocation Test ◽  
Hospitalized Patients ◽  
Penicillin Allergy ◽  
Full Time ◽  
Allergy Testing ◽  
Oral Provocation ◽  
Allergy Test ◽  
Oral Provocation Test

Background: False penicillin allergies lead to increased antimicrobial resistance, adverse effects, and health care costs by promoting the use of broad-spectrum antibiotics. The Infectious Diseases Society of America recommends the implementation of allergy testing. Objectives: The primary objective of this research was to estimate the number of pharmacist full-time equivalents (FTEs) required for an intervention aimed at determining penicillin allergy in hospitalized patients. Acceptance of pharmacists’ suggestions on antibiotic therapy are described. Methods: A quasi-experimental study was conducted in a 712-bed university hospital involving hospitalized patients with a suspected penicillin allergy and an infection treatable with penicillin. The time required for the intervention, which included a questionnaire, penicillin allergy testing (skin-prick test, intradermal injection, and oral provocation test), and recommendations on antibiotic therapy were measured to calculate the number of pharmacist FTEs. Results: A total of 55 patients were included. Scarification allergy testing was performed on 37, intradermal allergy test on 33, and oral provocation test on 26 patients. The intervention ruled out penicillin allergy in 26 patients, with no serious adverse effects. The intervention was associated with a median weekly pharmacist FTE of 0.15 (interquartile range = 0.12-0.25). The acceptance of pharmacists’ suggestions was high and led to 9 patients being switched to an antibiotic with a narrower spectrum of activity. Conclusions and Relevance: This study describes penicillin allergy testing and the number of median weekly hospital pharmacist FTEs required, which was approximately 0.15. These data may aid in the implementation of this safe intervention that promotes narrower-spectrum antibiotherapy.

Differences in the prevalence of positive penicillin allergy test results in children and adults

2021 ◽  
Author(s):  
Yasutaka Kuniyoshi ◽  
Yasushi Tsujimoto ◽  
Masahiro Banno ◽  
Shunsuke Taito ◽  
Takashi Ariie ◽  
...  
Keyword(s):  
Penicillin Allergy ◽  
Test Results ◽  
Allergy Test

scholarly journals Patient and Prescriber Views of Penicillin Allergy Testing and Subsequent Antibiotic Use: A Rapid Review

Antibiotics ◽  
2018 ◽  
Vol 7 (3) ◽  
pp. 71 ◽  
Author(s):  
Marta Wanat ◽  
Sibyl Anthierens ◽  
Christopher Butler ◽  
Judy Wright ◽  
Naila Dracup ◽  
...  
Keyword(s):  
English Language ◽  
Antibiotic Use ◽  
Penicillin Allergy ◽  
Rapid Review ◽  
Antibiotic Prescribing ◽  
Allergy Testing ◽  
Referral Criteria ◽  
Allergy Test ◽  
Prescribing Behaviour ◽  
Test Result

About 10% of U.K. patients believe that they are allergic to penicillin and have a “penicillin allergy label” in their primary care health record. However, around 90% of these patients may be mislabelled. Removing incorrect penicillin allergy labels can help to reduce unnecessary broad-spectrum antibiotic use. A rapid review was undertaken of papers exploring patient and/or clinician views and experiences of penicillin allergy testing (PAT) services and the influences on antibiotic prescribing behaviour in the context of penicillin allergy. We reviewed English-language publications published up to November 2017. Limited evidence on patients’ experiences of PAT highlighted advantages to testing as well as a number of concerns. Clinicians reported uncertainty about referral criteria for PAT. Following PAT and a negative result, a number of clinicians and patients remained reluctant to prescribe and consume penicillins. This appeared to reflect a lack of confidence in the test result and fear of subsequent reactions to penicillins. The findings suggest lack of awareness and knowledge of PAT services by both clinicians and patients. In order to ensure correct penicillin allergy diagnosis, clinicians and patients need to be supported to use PAT services and equipped with the skills to use penicillins appropriately following a negative allergy test result.

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