Incidence and risk factors of retinopathy of prematurity in a tertiary neonatal intensive care unit: Assiut University Hospital, Upper Egypt

PURPOSE: To study the incidence of retinopathy of prematurity (ROP) in a neonatal intensive care unit in Croatia and obtain information on risk factors associated with ROP. There have been limited studies on ROP in Croatia where the screening for ROP and its treatment is still insufficient and not introduced in many intensive care units. MATERIAL AND METHODS: This retrospective study included 247 premature infants admitted to the neonatal intensive care unit of University Hospital Split, over a 5-year period between January 2012, and December 2016. In this paper the relationship between clinical risk factors and the development of ROP was analyzed. RESULTS: The overall incidence for ROP was 23,9 % (59 infants), for Type 1 ROP was 9,3% (23 infants); for Type 2 ROP was 14,6% (36 infants). Median gestational age (GA) and birthweight (BW) were significantly lower among infants with ROP versus those without ROP (29: 23-34 vs. 31: 23-34,p<0,001 and 1,180:630-2,000 vs. 1485:590-2000, p<0,001 respectively). Multivariate analysis showed that only BW (p=0,029) and small for gestational age (SGA) (p=0,045) predicted the development of ROP. CONCLUSION: Birth weight and small for gestational age were the most significant risk factors for developing ROP. In comparison with studies from highly developed countries, infants with a much wider range of gestational age and birth weights are developing Type 1 ROP.

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Analysis of the Risk Factors Associated with Hearing Loss of Infants Admitted to a Neonatal Intensive Care Unit: A 13-Year Experience in a University Hospital in Korea

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17218082 ◽

2020 ◽

Vol 17 (21) ◽

pp. 8082

Author(s):

Kyu Young Choi ◽

Bum Sang Lee ◽

Hyo Geun Choi ◽

Su-Kyoung Park

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Hearing Loss ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Neonatal Intensive Care ◽

Significant Risk ◽

University Hospital ◽

Control Group ◽

Brainstem Response

Early detection of hearing loss in neonates is important for normal language development, especially for infants admitted to the neonatal intensive care unit (NICU) because the infants in NICU have a higher incidence of hearing loss than healthy infants. However, the risk factors of hearing loss in infants admitted to the NICU have not been fully acknowledged, especially in Korea, although they may vary according to the circumstances of each country and hospital. In this study, the risk factors of hearing loss in NICU infants were analyzed by using the newborn hearing screening (NHS) and the diagnostic auditory brainstem response (ABR) test results from a 13-year period. A retrospective chart review was performed using a list of NICU infants who had performed NHS from 2004 to 2017 (n = 2404) in a university hospital in Korea. For the hearing loss group, the hearing threshold was defined as 35 dB nHL or more in the ABR test performed in infants with a ‘refer’ result in the NHS. A four multiple number of infants who had passed the NHS test and matched the age and gender of the hearing loss group were taken as the control group. Various patient factors and treatment factors were taken as hearing loss related variables and were analyzed and compared. From the 2404 infants involved, the prevalence of hearing loss was 1.8% (n = 43). A comparison between the hearing loss group (n = 43) and the control group (n = 172) revealed that history of sepsis, peak total bilirubin, duration of vancomycin use, days of phototherapy, and exposure to loop-inhibiting diuretics were significantly different, and can be verified as significant risk factors for hearing loss in NICU infants.

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Microbiology and Risk Factors for Catheter Exit-Site and -Hub Colonization in Neonatal Intensive Care Unit Patients

Infection Control and Hospital Epidemiology ◽

10.1086/501913 ◽

2001 ◽

Vol 22 (6) ◽

pp. 357-362 ◽

Cited By ~ 24

Author(s):

Ludo M. Mahieu ◽

Jozef J. De Dooy ◽

Aimé O. De Muynck ◽

Guillaume Van Melckebeke ◽

Margareta M. Ieven ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Neonatal Intensive Care ◽

Strong Association ◽

University Hospital ◽

Exit Site ◽

Coagulase Negative Staphylococci ◽

Factors Associated

AbstractObjective:To identify risk factors and describe the microbiology of catheter exit-site and hub colonization in neonates.Design:During a period of 2 years, we prospectively investigated 14 risk factors for catheter exit-site and hub colonization in 862 central venous catheters in a cohort of 441 neonates. Cultures of the catheter exit-site and hub were obtained using semiquantitative techniques at time of catheter removal.Setting:A neonatal intensive care unit at a university hospital.Results:Catheter exit-site colonization was found in 7.2% and hub colonization in 5.3%. Coagulase-negative staphylococci were predominant at both sites. Pathogenic flora were found more frequently at the catheter hub (36% vs 14%;P<.05). Through logistic regression, factors associated with exit-site colonization were identified as umbilical insertion (odds ratio [OR], 8.1; 95% confidence interval [CI95], 2.35-27.6;P<.001), subclavian insertion (OR, 54.6; CI95, 12.2-244;P<.001), and colonization of the catheter hub (OR, 8.9; CI95,3.5-22.8;P<.001). Catheter-hub colonization was associated with total parenteral nutrition ([TPN] OR for each day of TPN, 1.056; CI95,1.029-1.083;P<.001) and catheter exit-site colonization (OR, 6.11; CI95, 2.603-14.34;P<.001). No association was found between colonization at these sites and duration of catheterzation and venue of insertion, physician's experience, postnatal age and patient's weight, ventilation, steroids or antibiotics, and catheter repositioning.Conclusion:These data support that colonization of the catheter exit-site is associated with the site of insertion and colonization of the catheter hub with the use of TPN. There is a very strong association between colonization at both catheter sites.

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Nosocomial Infections in Neonatal Intensive Care Unit In Pediatric Assiut University Hospital: Incidence and Risk Factors

Journal of High Institute of Public Health ◽

10.21608/jhiph.2008.22498 ◽

2008 ◽

Vol 38 (Proceedings) ◽

pp. 33-48

Author(s):

Asmaa Soliman ◽

Eman Mohamed ◽

Kawthar Fadel ◽

Samia Mohamed ◽

Enas Daef

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Nosocomial Infections ◽

Neonatal Intensive Care ◽

University Hospital

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Screening for Retinopathy of Prematurity in a Large Tertiary Neonatal Intensive Care Unit in Turkey: Frequency and Risk Factors

Ophthalmic Epidemiology ◽

10.3109/09286586.2011.615449 ◽

2011 ◽

Vol 18 (6) ◽

pp. 269-274 ◽

Cited By ~ 16

Author(s):

Yusuf Unal Sarikabadayi ◽

Ozge Aydemir ◽

Zuhal Tunay Ozen ◽

Cumhur Aydemir ◽

Levent Tok ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Neonatal Intensive Care Unit ◽

Retinopathy Of Prematurity ◽

Neonatal Intensive Care

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Retinopathy of prematurity- clinical profile on incidence, risk factors and outcome

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20204543 ◽

2020 ◽

Vol 7 (11) ◽

pp. 2189

Author(s):

Purva Shah ◽

Ketan Gadhvi ◽

Bharat Muliya

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Intensive Care ◽

Birth Weight ◽

Low Birth Weight ◽

Neonatal Intensive Care Unit ◽

Retinopathy Of Prematurity ◽

Neonatal Intensive Care ◽

Tertiary Hospital ◽

Antenatal Steroids

Background: Retinopathy of prematurity is one of the important causes of preventable blindness in the world. Thereby timely screening, diagnosis and hence treatment is of utmost importance.Methods: This study was done in the neonatal intensive care unit of tertiary hospital, Surendranagar. Study design being observational, data collected from clinical examination and records of the preterm babies <34 weeks and low birth weight babies <1.5 kg and further screened them for retinopathy of prematurity. The incidence of ROP in the neonatal intensive care unit (NICU), risk factors which predispose to ROP (Retinopathy of prematurity) and outcome of these cases were analysed.Results: As per this study, ROP was found to be more common in <30 weeks gestation and<1 kg neonate, and found to be associated with oxygen exposure, blood product use, antenatal steroids and surfactant.Conclusions: The analysis of the incidence and risk factors, will henceforth help in identifying and acting on time, thereby improving overall outcome of the preterm and low birth weight new-borns.

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