Validating the use of U-tool as a novel method for measuring the corneal diameter in infants screened for congenital glaucoma

Purpose: To identify psychosocial indicators and evaluate the filtering surgeries impacts on quality of life (QOL) of children with primary congenital glaucoma (PCG) and their family. Methods: Parents of children with bilateral PCG who underwent filtering surgery were included. Data were collected through: (a) psychological inquiry to determine psychosocial indicators; (b) Children’s Visual Function Questionnaire (CVFQ). The associations between the CVFQ scores and visual acuity, intraocular pressure, optic disk cupping, horizontal corneal diameter, axial length, number of surgeries, and hypotensive eye drops were investigated. The statistical significance level was considered as p ⩽ 0.05. Results: The mean age of the nine mothers interviewed and their children (six boys and three girls) was 29 ± 5 years and 35 ± 18 months, respectively. The psychosocial indicators determined were: emotional impact of the diagnosis, disease knowledge, mother and family’s feelings on facing the surgical treatment, surgical result comprehension, treatment adherence, child's emotional and behavioral reactions, social support, and future expectations. In CVFQ analysis, QOL score was strongly associated with visual acuity ( r = −0.79; p = 0.01). Besides the treatment score was correlated to intraocular pressure ( r = −0.68; p < 0.05), optic disk cupping ( r = −0.85; p = 0.03), and corneal diameter ( r = −0.69; p = 0.02). Correlations were not found for number of surgeries and eye drops. Conclusions: This study confirmed the PCG surgical treatment impact on QOL and determined psychosocial indicators which may favor the suitable actions in psychological treatment and follow-up of the children and families.

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Comparison of ocular axis and corneal diameter between entropion and non-entropion eyes in children with congenital glaucoma

World Journal of Clinical Cases ◽

10.12998/wjcc.v9.i18.4637 ◽

2021 ◽

Vol 9 (18) ◽

pp. 4637-4643

Author(s):

Yue Wang ◽

Zhi-Jia Hou ◽

Huai-Zhou Wang ◽

Man Hu ◽

Yu-Xin Li ◽

...

Keyword(s):

Congenital Glaucoma ◽

Corneal Diameter

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Trabeculectomy in Congenital Glaucoma; Experience in Helpers Eye Hospital Quetta

Pakistan Journal of Ophthalmology ◽

10.36351/pjo.v36i3.1043 ◽

2020 ◽

Vol 36 (3) ◽

Author(s):

Mahtab Mengal ◽

M Afzal Khan ◽

Aimal Khan ◽

Manzoor Ahmed ◽

Rabia Khawar Chaudhry ◽

...

Keyword(s):

General Anesthesia ◽

Trauma Surgery ◽

Case Series ◽

Posterior Segment ◽

Congenital Glaucoma ◽

Primary Congenital Glaucoma ◽

Effective Operation ◽

Operative Complications ◽

Corneal Diameter

Purpose: To evaluate outcomes of trabeculectomy in terms of IOP control and its safety in terms of peroperativeand post-operative complications in Primary Congenital Glaucoma.Study Design: Interventional Case-Series.Place and Duration of Study: Helpers Eye Hospital, Quetta, from June 2017 to December 2018.Material and Methods: Thirty eyes of 17 patients were included in this case series after diagnosis of primarycongenital glaucoma. Patients with secondary congenital glaucoma due to trauma, surgery, inflammation, SturgeWeber Syndrome, Neurofibromatosis, cataract, uveitis, aphakia and pseudophakia were excluded from the study.Informed consent was taken from parents. Examination under anesthesia was done before surgery to recordpreoperative IOP, corneal diameter and anterior and posterior segment abnormalities. Primary trabeculectomywas done. Post-operative IOP and corneal diameter was recorded at 1st, 3rd and 6th month and every 6 monthsthereafter under general anesthesia. IOP at 12th month of surgery was the final outcome which was consideredsignificant if IOP was less than 21 mm Hg with stable corneal diameters.Results: Mean preoperative IOP was 25.8 mm Hg. Twenty-three (76.66%) eyes out of 30 eyes were consideredsuccessful with mean IOP of 15.3 mm Hg at last follow-up while 7 (23.33%) cases of failure were observed withpostoperative mean IOP of 27.71 mm Hg. These patients underwent additional surgeries to control IOP.Hyphema was the only complication observed in this study. Postoperative cataract developed in 5 eyes.Conclusion: Primary trabeculectomy is an effective operation and safe surgery for primary congenital glaucoma

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Progression in pediatric glaucoma: Lessons learnt from 8 years’ follow-up

Medical hypothesis discovery and innovation in ophthalmology ◽

10.51329/mehdiophthal1432 ◽

2021 ◽

Vol 10 (3) ◽

pp. 138-145

Author(s):

Farideh Sharifipour ◽

Elahe Arasteh ◽

Maryam Hajizadeh ◽

Atefe Mahdian-Rad ◽

Mohammad Sadegh Mirdehghan

Keyword(s):

Systemic Disease ◽

Corneal Thickness ◽

Glaucoma Surgery ◽

Secondary Glaucoma ◽

Congenital Glaucoma ◽

Treatment Modalities ◽

Glaucoma Progression ◽

Pediatric Glaucoma ◽

Corneal Diameter

Background: Surgical procedures are used as 1 of the main treatment modalities for pediatric glaucoma, even though progression may occur. In this study, we aimed to investigate the risk factors affecting the progression of pediatric glaucoma.Methods: In this retrospective cohort study, we reviewed the medical records of patients diagnosed with pediatric glaucoma between April 2009 and March 2017. Pediatric glaucoma patients who underwent regular follow-up for at least 1 year were included. Demographics, intraocular pressure (IOP), central corneal thickness (CCT), axial length (AL), cup-to-disc ratio (C/D ratio), corneal diameter, type of glaucoma, age at time ofdiagnosis, and age at surgery were recorded. Progression was defined as an increase in AL > 2 mm, C/D ratio > 0.2, or corneal diameter > 1 mm during 1 year of follow-up.Results: Eighty-three eyes from 46 patients were included: 37 eyes (45%) with primary congenital glaucoma (PCG), 46 eyes (55%) with secondary glaucoma, and 27 of these 83 eyes (32.5%) showed progression. Progression was comparable between eyes with PCG and secondary glaucoma (PCG, 22%; secondary glaucoma, 41%; P = 0.152). Age at the time of diagnosis and age at the time of the first surgery were significantly lower in the eyes with progression (P = 0.046 and 0.012, respectively). The mean ± standard deviation of surgeries in progressed versus non-progressed eyes was 1.88 ± 1.1 versus 1 ± 0.8 (P = 0.015). The frequency of comorbid systemic disease was significantly higher in patients with glaucoma progression (P = 0.043). The progressed and non-progressed eyes were comparable in terms of other demographic characteristics and ocular parameters (allP > 0.05).Conclusions: Pediatric glaucoma patients who were younger at the time of diagnosis and the first glaucoma surgery and those with comorbid systemic disease are at higher risk of glaucoma progression. These findings are useful for clinicians when counseling parents of children with pediatric glaucoma about disease outcomes. However, future prospective studies with larger sample sizes and longer follow-up periods are needed to confirm our findings.

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PRIMARY CONGENITAL GLAUCOMA;

The Professional Medical Journal ◽

10.29309/tpmj/2019.26.05.3482 ◽

2019 ◽

Vol 26 (05) ◽

Author(s):

Shabeer Ahmad Bhutto ◽

Naeem Akhtar Katpar ◽

Safdar Ali Abbasi

Keyword(s):

Case Series ◽

Congenital Glaucoma ◽

Slit Lamp ◽

Success Rates ◽

Interventional Study ◽

Primary Congenital Glaucoma ◽

Medical College ◽

Surgical Expertise ◽

Paediatric Ophthalmology ◽

Corneal Diameter

Objectives: The objective of this study is to compare the surgical outcome between modified trabeculotomy v/s combined modified trebeculotomy & trebeculectomy in primary congenital glaucoma. Study Design: Interventional case series. Setting: Paediatric Ophthalmology Department, Chandka Medical College. Period: June 2016 to June 2017. Method: This is a comparative study done to compare the outcomes of trabeculectomy and combined trabeculotomy and trabeculectomy. For comparison a prospective interventional study conducted in paediatric ophthalmology, Chandka Medical College during the duration of August 2014 to August 2016 was chosen. After examination by slit lamp and under anaesthesia, combined modified trabeculotomy and trabeculectomy was performed. Results: A total of 45 eyes of 29 patients with primary congenital glaucoma underwent modified trabeculotomy, 15 (51.72%) were males and 14 (48.28%) were females. Mean age of patients was 2.29 ± 3.70 years. On the other hand, combined modified trabeculotomy and trabeculectomy was performed in 22 eyes of 17 patients out of which 08 (47.06%) were males and 09 (52.94%) were females. Mean age ± standard deviation was 3.37 ± 4.40 years. Statistically significant reduction in IOP, corneal diameter and axial length were found. Conclusion: Combined trabeculotomy-trabeculectomy has better outcomes than trabeculotomy alone. It requires greater surgical expertise and time. Higher success rates are reported in previous studies due to dual outflow of aqueous humour.

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Congenital Thyrotoxicosis with Congenital Glaucoma: A Case Report

TAJ Journal of Teachers Association ◽

10.3329/taj.v20i1.3094 ◽

1970 ◽

Vol 20 (1) ◽

pp. 64-66

Author(s):

MI Bari ◽

ME Hoque ◽

T Alam ◽

KM Choudhury

Keyword(s):

Intraocular Pressure ◽

Case Report ◽

Preterm Neonate ◽

Elevated Serum ◽

Thyroid Stimulating Hormone ◽

Congenital Glaucoma ◽

Corneal Oedema ◽

First Case ◽

Corneal Diameter ◽

Stimulating Hormone

A case of preterm neonate with congenital thyrotoxicosis associated with congenital glaucoma is reported. Her mother had undiagnosed thyrotoxicosis. The diagnosis of thyrotoxicosis in the neonate was confirmed by an elevated serum tri-iodothyronine (T3) level of 8.09 nmol/L, thyroxin (T4) level of 3.09 nmol and thyroid stimulating hormone (TSH) level 0.16mu/L. Congenital glaucoma was confirmed by increased intraocular pressure (IOP) which was 42.1 mmHg in right eye and 38.2 mm Hg in left eye. Corneal diameter was increased which was 13 mm in both eyes. Corneal oedema and Haab striae were also present. Probably, this is the first case of congenital thyrotoxicosis associated with congenital glaucoma reported in Bangladesh. doi: 10.3329/taj.v20i1.3094 TAJ 2007; 20(1): 64-66

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To evaluate effect of intraocular pressure control on central corneal thickness, horizontal corneal diameter and axial length in primary congenital glaucoma

Indian Journal of Clinical and Experimental Ophthalmology ◽

10.18231/j.ijceo.2021.076 ◽

2021 ◽

Vol 7 (2) ◽

pp. 385-388

Author(s):

Gunjan P Tank ◽

Kamini M Prajapati ◽

Rupal Bhatt ◽

Amita Chauhan ◽

Mariam Mansuri ◽

...

Keyword(s):

Intraocular Pressure ◽

Axial Length ◽

Central Corneal Thickness ◽

Corneal Thickness ◽

Pressure Control ◽

Posterior Segment ◽

Congenital Glaucoma ◽

Common Symptom ◽

Primary Congenital Glaucoma ◽

Corneal Diameter

To evaluate the effect of intraocular pressure (IOP) on central corneal thickness (CCT), horizontal corneal diameter (HCD), axial length (AL) in patients with primary congenital glaucoma (PCG) after antiglaucoma surgery. In this hospital based interventional study 36 patients (66 eyes) of PCG who underwent antiglaucoma surgery were included in the study. For each patient visual acuity, anterior and posterior segment examination, IOP, AL, CCT, HCD and refraction (in clear media) were recorded pre and post operatively (3 weeks, 3 months, 6 months). B scan ultrasonography was done to measure AL and to rule out posterior segment pathology. Surgery was performed by a glaucoma expert (by a single surgeon). Bilateral involvement was present in 83.33% with the most common symptom being photophobia and watering (30.56% each). The mean IOP, CCT, HCD, VCD and AL before surgery were 26.88+/-2.78 mmHg, 614.38+/-89.41 µ, 14.41+/-1.26mm, 13.19+/-1.46mm and 24.78+/-2.21mm and at 6 months were 13.85+/-1.93 mmHg, 548.56+/-63.13 µ, 14.62+/-0.49 mm, 13.34+/-1.10 mm and 25.73+/-1.36mm respectively. 59.1% of the patients had corneal clearing at 6 months. Control of IOP affects various parameters of eye like CCT, HCD and AL. Early surgery is the definitive line of management for controlling IOP in PCG patients.

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Relationship between corneal sensitivity, corneal thickness, corneal diameter, and intraocular pressure in normal cats and cats with congenital glaucoma

Veterinary Ophthalmology ◽

10.1111/vop.12558 ◽

2018 ◽

Vol 22 (1) ◽

pp. 4-12 ◽

Cited By ~ 4

Author(s):

Mary R. Telle ◽

Nickolas Chen ◽

Daniel Shinsako ◽

Julie A. Kiland ◽

Kazuya Oikawa ◽

...

Keyword(s):

Intraocular Pressure ◽

Corneal Thickness ◽

Congenital Glaucoma ◽

Corneal Sensitivity ◽

Corneal Diameter

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The removal and morphology of intact biofilms from implanted venous access devices

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100141470 ◽

1995 ◽

Vol 53 ◽

pp. 1020-1021

Author(s):

M.A. Gregory ◽

G.P. Hadley

Keyword(s):

Patient Selection ◽

Surgical Oncology ◽

Venous Access ◽

Common Procedure ◽

Indwelling Catheters ◽

Careful Patient ◽

Novel Method ◽

The Subject ◽

Vascular Catheters ◽

Venous Access Devices

The insertion of implanted venous access systems for children undergoing prolonged courses of chemotherapy has become a common procedure in pediatric surgical oncology. While not permanently implanted, the devices are expected to remain functional until cure of the primary disease is assured. Despite careful patient selection and standardised insertion and access techniques, some devices fail. The most commonly encountered problems are colonisation of the device with bacteria and catheter occlusion. Both of these difficulties relate to the development of a biofilm within the port and catheter. The morphology and evolution of biofilms in indwelling vascular catheters is the subject of ongoing investigation. To date, however, such investigations have been confined to the examination of fragments of biofilm scraped or sonicated from sections of catheter. This report describes a novel method for the extraction of intact biofilms from indwelling catheters.15 children with Wilm’s tumour and who had received venous implants were studied. Catheters were removed because of infection (n=6) or electively at the end of chemotherapy.

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