scholarly journals Prevalence of herpesviruses in periodontal disease of the North Indian population: A pilot study

2020 ◽  
Vol 24 (2) ◽  
pp. 163
Author(s):  
Rameshwari Singhal ◽  
Amita Jain ◽  
Pavitra Rastogi
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Neelam Tia ◽  
Moti Lal ◽  
I. S. Gambhir

Abstract Background Healthy aging perceives human longevity probably due to carrying the defensive genes. Forkhead box O (FOXO) transcription factors provide the most convincing example of a conserved genetic pathway at the point between aging and cancer. This pilot study was performed to examine the single nucleotide variants rs2253310 and rs4946936 of the Forkhead box O 3 (FOXO3 gene) in octogenarians and gastrointestinal tract (GIT) cancer patients in the north Indian population. Main body In silico mutational analysis of the FOXO3 gene in 25 participants. Two single nucleotide variants (SNVs) g.7556C>G (rs2253310) heterozygous and g.122284T>C (rs4946936) homozygous observed and reported previously. However, there is a common association of these SNVs in different ethnic groups. No significant differences in the genotype and allele frequencies for the study groups observed. Short conclusion This study observes two single nucleotide variants, g.7556C>G (rs2253310) and g.122284T>C (rs4946936), of the FOXO3 gene in the study groups which influence human longevity. Longevity-associated FOXO3 variants may be associated with GIT cancer in the north Indian population. As a result, looking for genes linked to longevity will lead to discovering new cancer targets. Further studies with a large population are necessary to elucidate the role of the FOXO3 gene in octogenarians.


2018 ◽  
Vol 34 (3) ◽  
pp. 281-285 ◽  
Author(s):  
Surabhi Yadav ◽  
Salman Akhtar ◽  
Surendra K. Agarwal ◽  
Gauranga Majumdar ◽  
Suman Vimal ◽  
...  

2021 ◽  
Vol 12 (1) ◽  
pp. 13
Author(s):  
Swati Kapoor ◽  
AjitKumar Jaiswal ◽  
Girish Chaudhary ◽  
Abhimanyu Kochhar ◽  
JasmeetKaur Ryait ◽  
...  

2012 ◽  
Vol 42 (5) ◽  
pp. 151 ◽  
Author(s):  
Anika Daing ◽  
Sarvendra Vikram Singh ◽  
Charanjeet Singh Saimbi ◽  
Mohammad Akhlaq Khan ◽  
Srikanta Kumar Rath

2009 ◽  
Vol 28 (9) ◽  
pp. 443-449 ◽  
Author(s):  
Ranbir C. Sobti ◽  
Pushpinder Kaur ◽  
Satinder Kaur ◽  
Ashok K. Janmeja ◽  
Surinder K. Jindal ◽  
...  

2015 ◽  
Vol 1 (5) ◽  
pp. 233
Author(s):  
Dharmveer Yadav ◽  
Monika Gupta ◽  
Sandhya Mishra ◽  
Praveen Sharma

Objective: Reference intervals are an essential part of laboratory medicine. Current study was planned to evaluate renal parameters in the healthy defined group of individuals which would serve as reference values of renal parameters for the North Indian population from Rajasthan.Design & Methods: Present study was conducted on 2021 apparently healthy individuals of North Indian origin ranging in age from 15-60 years, were selected randomly using defined criteria. Fasting samples were analyzed for Urea, Creatinine, Uric Acid, Sodium, Potassium and Chloride. Data were analyzed for middle 95 percentile (2.5th-97.5th percentile), median and 95% confidence interval using SPSS software package version 10.0.Result: RI for Urea, Creatinine and uric acid were lower in female (16-42mg/dl, 0.6-1.2mg/dl, 2.4-6.8mg/dl) as compared to male (17.00-44.35mg/dl, 0.7-1.5mg/dl, 2.8-7.2mg/dl). There was a progressive increase in urea, uric acid and Creatinine with increase in age. Though no appreciable differences could be observed in respect to most of renal parameters in rural versus urban, a wider range for uric acid was observed in urban population (2.50-7.20mg/dl). Except for Na+, K+ and Cl-, rest of parameters i.e. urea, creatinine, uric acid were higher range in obese as compared to non obese (17-45 Vs 17-44, 0.66-1.5 Vs 0.60-1.40, 2.5-7.4 Vs 2.5-7.0). Uric acid level was also found to be higher in non vegetarian population (2.6-7.5mg/dl).Conclusion: Findings of this study provide sex, age, BMI, habitat and diet specific renal function reference values to be used for North Indian population.


2019 ◽  
Vol 405 ◽  
pp. 130
Author(s):  
S. Misra ◽  
P. Talwar ◽  
A. Mishra ◽  
A. Kumar ◽  
P. Kumar ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document