An investigation of the effects of the mean platelet volume, platelet distribution width, platelet/lymphocyte ratio, and platelet counts on mortality in patents with sepsis who applied to the emergency department

2018 ◽  
Vol 21 (5) ◽  
pp. 667 ◽  
Author(s):  
M Ustundag ◽  
M Orak ◽  
Y Karakoç ◽  
Y Yildirim ◽  
MK Celen ◽  
...  
Keyword(s):  
Emergency Department ◽  
Mean Platelet Volume ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Lymphocyte Ratio ◽  
Platelet Counts ◽  
Platelet Lymphocyte Ratio ◽  
The Mean

scholarly journals Effect of neonatal sepsis on platelet counts and their indices

2020 ◽  
Vol 8 (1) ◽  
pp. 114
Author(s):  
Gonesh N. Mevundi ◽  
Harsha S.
Keyword(s):  
Staphylococcus Aureus ◽  
Blood Culture ◽  
Neonatal Sepsis ◽  
Mean Platelet Volume ◽  
Causative Organism ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Platelet Counts ◽  
Common Organism

Background: Neonatal septicemia is a clinical syndrome characterized by signs and symptoms of infection with or without accompanying bacteremia in the first month of life. Objective of the study was to know the effect of sepsis on platelet counts and their indices.Methods: The study was carried out over a period of one and half year from December 2015 to July 2017 at Sangmeshwar and Basaveshwar hospital attached to M. R. medical college, Kalaburagi. 100 cases were considered for this study after proper screening for complete blood count (CBC), platelet count and their indices like mean platelet volume, platelet distribution width and C-reactive protein (CRP) and blood culture in neonates admitted in our neonatal intensive care unit (NICU) with proven sepsis.Results: A total of 100 neonates with blood culture positive for bacterial cases were considered for the study. Early onset septicaemia (59%) was more common than late onset septicaemia (41%). Out of 100 cases 57% cases had growth of gram negative organisms, 40% had growth of gram positive organisms and 3% had growth of fungal. Tachypnea (27%), lethargy (20%) and refusal of feeds (8%) were the commonest clinical presentation followed by, fever (6%), convulsions (5%) and jaundice (5%). 60% neonates had thrombocytopenia of varying severity. Staphylococcus aureus was the most common organism associated with thrombocytopenia (43.3%). Mean platelet volume (MPV) was high in 85% of cases and platelet distribution width (PDW) was high in 96% of cases.Conclusions: The present study highlights the association of thrombocytopenia, mean platelet volume and platelet distribution width with causative organism in proven neonatal sepsis. Staphylococcus aureus was the most common organism causing thrombocytopenia in our NICU.

scholarly journals Evaluation of the Mean Platelet Volume and Platelet Distribution width in Children with Familial Mediterranean Fever

2020 ◽  
Vol 18 (2) ◽  
pp. 208-219
Author(s):  
Fatma Duksal ◽  
Ahmet Sami Güven ◽  
Mesut Arslan ◽  
Melih Timucin Dogan ◽  
Utku Aygüneş
Keyword(s):  
Familial Mediterranean Fever ◽  
Mean Platelet Volume ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Mediterranean Fever ◽  
The Mean

scholarly journals Complete Blood Count Parameters in Arthritis

2020 ◽  
Vol 22 (3) ◽  
pp. 99-105
Author(s):  
Shiva Raj KC ◽  
S Shrestha ◽  
G KC ◽  
P Gyawali ◽  
S Dahal ◽  
...  
Keyword(s):  
Neutrophil Count ◽  
Mean Platelet Volume ◽  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Differential Count ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio

Osteoarthritis, rheumatoid arthritis, and gout are frequently encountered diseases in the orthopedic clinic. CRP is done to evaluate and monitor these disease processes. This study aimed to evaluate total leukocyte count with differential count, neutrophil/lymphocyte ratio, platelet, platelet/lymphocyte ratio, mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit in patients with arthritis. This was a cross-sectional study conducted at KIST Medical College, Teaching Hospital from 15 Ashad 2075 to 14 Ashad 2076. The patient’s demographic data and laboratory findings: total leukocyte count, differential count, hemoglobin, platelet count, plateletcrit, mean platelet volume, platelet distribution width, and plateletcrit. CRP, ESR, RA factor/anti-CCP, and Uric acid tests were also performed. Among 67 patients, osteoarthritis was seen in 53 (79.1%), rheumatoid arthritis among 11(16.4%), and Gout among 3(4.5%). The ROC area under the curve was within acceptable limits for the neutrophil count, neutrophil/lymphocyte ratio, mean platelet volume, platelet distribution width. The sensitivity and specificity of the neutrophil count were 75% and 62% respectively (cut-off: 64.5%). Neutrophil/Lymphocyte ratio was increased and correlated with CRP (p-value: <0.001). PDW had a sensitivity of 90% and specificity of 83.0% (cut-off: 16.8 CV). For MPV, the sensitivity was 80% and specificity was 81% (cut-off: 9.1 fL). At 1.92 cut-off value, the sensitivity and specificity of neutrophil/lymphocyte ratio were 80.0% and 62.0% respectively. CBC parameters can provide an important clue to the treating physician, which helps to manage a patient with arthritis effectively. Neutrophil count, Neutrophil/Lymphocyte ratio, MPV, and PDW correlated with other inflammatory biomarkers and can be used to assess the patient with arthritis.

scholarly journals COMPARISON OF PLATELET COUNTS SHOWN BY AUTOMATIC HAEMATOLOGY ANALYSERS AND COUNTS MEASURED MANUALLY IN POPULATION OF MOUNTAINOUS HILLY REGION OF CHENAB VALLEY ATTENDING OPD ON ROUTINE BASIS IN GMC DODA. ASSOCIATED HOSPITAL

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sumat Ul Khurshid ◽  
Nazia Tabbasum
Keyword(s):  
Peripheral Blood ◽  
Mean Platelet Volume ◽  
Blood Smear ◽  
Peripheral Blood Smear ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width ◽  
Platelet Indices ◽  
Platelet Counts ◽  
Hilly Region

In clinical practice it is very important to perform the platelet counts.  The estimation of platelet counts from peripheral blood smears is an accurate method and provides adequate quality assurance in traditional methods as the automated cell counters are not available at all hospital setups especially in rural areas. In modern era use of   automated analyzers based on impedance technology has resulted in   improvement of accuracy and helps in measurement of platelet indices such as Mean Platelet Volume (MPV) Plateletcrit (PCT) and Platelet Distribution Width (PDW). However, both the methods have certain limitations. Platelet counts were estimated on a 5-part Differential Automated Hematology Analyzer and manually on Leishman stained peripheral blood SMEAR. Aims & Objective: 1. This study was conducted to compare platelet counts by peripheral blood  smear method and automated method in patients  attending OPD on routine basis in a mountainous hilly region of  J&k . It also aims to study the relation, if any, between the platelet count (automated) and platelet indices like Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) and to assess the possible role of these parameters in certain defined situations. Materials and methods: A prospective study was conducted in a tertiary care hospital on 200 Ethylene Diamine Tetra Acetic acid (EDTA) anticoagulated blood samples. Samples were evaluated by 5-Part differential automated hematology analyser using impedance counting method and by examination of peripheral blood smear method (PBF). Results: In thrombocytopenic patients, the platelet count assessed by automated analyzer revealed an inverse relation with Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) and showed large granular and giant platelets on PBS. Conclusion: Automated hematology analyzer is essential   for immediate   and accurate complete blood count evaluation but blood samples showing erroneous results or low platelet counts on analyzer should be confirmed on peripheral blood smear. The platelet indices like Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) can point to the underlying pathology especially in cases of thrombocytopenia. Keywords: Automated analyser, Peripheral blood smear, MPV, PDW, large granular platelets.

Investigation of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and mean platelet volume in patients with tinnitus

2018 ◽  
Vol 132 (2) ◽  
pp. 129-132 ◽  
Author(s):  
B Ulusoy ◽  
K Bozdemir ◽  
M Akyol ◽  
H İ Mişe ◽  
A Kutluhan ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Statistical Significance ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Platelet To Lymphocyte Ratio ◽  
Distribution Width ◽  
Significance Level ◽  
Lymphocyte Ratio

AbstractObjective:This study aimed to evaluate patients with tinnitus in terms of mean platelet volume and platelet distribution width, and to explore neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, recently reported in the literature as being possible inflammation markers.Methods:This study comprised 64 tinnitus patients and 64 age-matched healthy controls. Statistical significance level was accepted as p < 0.05.Results:Mean platelet volume (t = 3.245, p = 0.002) and platelet distribution width (Z = 3.945, p < 0.001) were significantly higher in the patient group than the control group.Conclusion:The results suggest that a prothrombotic condition might play a role in the pathophysiology of tinnitus.

Sign in / Sign up

Export Citation Format

Share Document