scholarly journals Glutathione deficiency in COVID19 illness-does supplementation help?

2021 ◽  
Vol 15 (4) ◽  
pp. 458
Author(s):  
Abhijit Nair ◽  
Praveen Sharma ◽  
ManishKumar Tiwary
Blood ◽  
1983 ◽  
Vol 61 (2) ◽  
pp. 373-377 ◽  
Author(s):  
JE Smith ◽  
K Moore ◽  
M Arens ◽  
GA Rinderknecht ◽  
A Ledet

Abstract A dog with persistent elliptocytosis was studied. The dog had membrane protein band 4.1 deficiency, microcytosis, shortened erythrocyte lifespan, increased osmotic sensitivity, and a mild glutathione deficiency. Erythrocyte deformability and membrane stability were adversely effected. The dog's parents had decreased band 4.1, decreased stability, and some elliptocytosis. This disorder in dogs closely resembles human patients with band 4.1 deficiency and should provide a valuable animal model to study the erythrocyte membrane cytoskeleton.


1996 ◽  
Vol 9 (2) ◽  
pp. 119-122 ◽  
Author(s):  
J. Thanislass ◽  
M. Raveendran ◽  
N. Sivasithamparam ◽  
H. Devaraj

2000 ◽  
Vol 32 ◽  
pp. 88
Author(s):  
I. Grattagliano ◽  
G. Vendemiale ◽  
B.H. Lauterburg ◽  
E. Altomare

2011 ◽  
Vol 25 (3) ◽  
pp. 323-332 ◽  
Author(s):  
Yuehua Fang ◽  
Julie Favre ◽  
Magalie Vercauteren ◽  
Brigitte Laillet ◽  
Isabelle Remy-Jouet ◽  
...  

2017 ◽  
Vol 113 ◽  
pp. 236-243 ◽  
Author(s):  
Nina Dickerhof ◽  
John F. Pearson ◽  
Teagan S. Hoskin ◽  
Luke J. Berry ◽  
Rufus Turner ◽  
...  

2008 ◽  
Vol 20 (4) ◽  
pp. 470-474 ◽  
Author(s):  
J. GUSTAFSSON ◽  
B. CARLSSON ◽  
A. LARSSON

Blood ◽  
1996 ◽  
Vol 87 (5) ◽  
pp. 2071-2074 ◽  
Author(s):  
A Hirono ◽  
H Iyori ◽  
I Sekine ◽  
J Ueyama ◽  
H Chiba ◽  
...  

Abstract Three unrelated Japanese patients with chronic nonspherocytic hemolytic anemia wer found to have marked deficiency of red blood cell (RBC) reduced glutathoine (GSH) (4.4%, 13.1%, and 6.9% of normal, respectively). A panel of RBC enzyme assays showed that one patient had decreased glutathione synthetase activity and the other two were moderately deficient in gamma-glutamylcystine synthetase. Some family members of each patient showed mild deficiency of the respective enzymes. RBCs of these patients also showed a decreased level of glutathione-S-transferase as in previously described GSH-deficient cases. Hemolytic anemia was their only manifestation, and neither 5- oxoprolinemia nor 5-oxoprolinuria, which are usually associated with to generalized type of glutathione synthetase deficiency, was noted in our patients.


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