Ankle–Brachial Index, plasma homocysteine, and brachial-ankle pulse wave velocity are important indicators in the diagnosis of early stage lower-extremity arterial occlusive disease

2019 ◽  
Vol 4 (1) ◽  
pp. 2
Author(s):  
Wangde Zhang ◽  
Tan Li ◽  
Yang Zhang
2011 ◽  
Vol 18 (6) ◽  
pp. 790-796 ◽  
Author(s):  
Peter Wohlfahrt ◽  
Daniel Palouš ◽  
Michaela Ingrischová ◽  
Alena Krajčoviechová ◽  
Jitka Seidlerová ◽  
...  

Background: Ankle brachial index (ABI) has been increasingly used in general practice to identify individuals with low ABI at high cardiovascular risk. However, there has been no consensus on the clinical significance of high ABI. The aim of our study was to compare aortic stiffness as a marker of cardiovascular risk in individuals with low (<1.0), normal (1.0–1.4), and high ABI (>1.4). Methods: A total of 911 individuals from the Czech post-MONICA study (a randomly selected 1% representative population sample, aged 54 ± 13.5 years, 47% of men) were examined. ABI was measured using a handheld Doppler and aortic pulse wave velocity (aPWV) using the Sphygmocor device. Results: Of the 911 individuals, 28 (3.1%) had low ABI and 23 (2.5%) high ABI. There was a U-shaped association between aPWV and ABI. aPWV was significantly higher in individuals with low and high ABI compared with the normal ABI group (11.1 ± 2.8, 8.3 ± 2.3, p < 0.001; 10.8 ± 2.5, 8.3 ± 2.3 m/s, p < 0.001, respectively). In a model adjusted for age, sex, systolic, diastolic, mean blood pressure and examiner, aPWV remained increased in both extreme ABI groups compared with the normal ABI group. In logistic regression analysis, aPWV together with glucose level, male sex, and a history of deep venous thrombosis were independent predictors of high ABI, while cholesterol was not. Conclusion: This is the first study showing increased aortic stiffness in individuals with high ABI, presumably responsible for increased left ventricular mass described previously in this group. These findings suggest increased cardiovascular risk of high ABI individuals.


2006 ◽  
Vol 49 (7) ◽  
pp. 769 ◽  
Author(s):  
Sun Young Joo ◽  
Ki Young Cho ◽  
Su Jin Cho ◽  
Young Mi Hong

2004 ◽  
Vol 5 (1) ◽  
pp. 136-137
Author(s):  
R. McMahon ◽  
J. Woodside ◽  
I. Young

2017 ◽  
Vol 24 (11) ◽  
pp. 1167-1173 ◽  
Author(s):  
Hayato Matsushima ◽  
Naohisa Hosomi ◽  
Naoyuki Hara ◽  
Takeshi Yoshimoto ◽  
Shuichiro Neshige ◽  
...  

2007 ◽  
Vol 30 (10) ◽  
pp. 965-970 ◽  
Author(s):  
Ho-Ming SU ◽  
Jer-Ming CHANG ◽  
Feng-Hsien LIN ◽  
Szu-Chia CHEN ◽  
Wen-Chol VOON ◽  
...  

2004 ◽  
Vol 46 (4) ◽  
pp. 398-402 ◽  
Author(s):  
Reiki Ooyanagi ◽  
Shigeto Fuse ◽  
Hideshi Tomita ◽  
Motoki Takamuro ◽  
Norihisa Horita ◽  
...  

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