Activity Level Assessment of Wheelchair Users Using Smart Cushion

Author(s):  
Congcong Ma ◽  
Raffaele Gravina ◽  
Wenfeng Li ◽  
Yu Zhang ◽  
Qimeng Li ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Diego E. Arias ◽  
Esteban J. Pino ◽  
Pablo Aqueveque ◽  
Dorothy W. Curtis

This paper presents an assistive device for wheelchair users with severe disability. It consists of several sensors deployed on a wheelchair, able to sense pressure relief habits, activity level, vital signs, and ambient conditions. A pilot study was conducted to evaluate the potential capabilities of the system and the feasibility of implementing alarms. During a period of two weeks, six full-time wheelchair users were monitored. Results show that the system is able to capture pressure relief patterns and tilt-in-space usage, a mechanism required to avoid pressure ulcers. Data analysis shows that none of the volunteers fully complied with the tilting recommendations. It also shows varied activity levels, both within and between patients, indicating their engagement in daily activities. The system is also able to estimate heart and respiration rate during passive activities (e.g., watching TV and/or resting). Also, high temperatures in summer were monitored while patients were outside, to prevent heatstroke events. All the monitored variables are acquired with unobtrusive sensors, producing no discomfort to the patient and providing valuable information for better care. The final recommendation and alarm system is implemented in a single board computer, to be embedded in the wheelchair.


Author(s):  
Yoshio Tanimoto ◽  
Kuniharu Nanba ◽  
Kazunari Furusawa ◽  
Hideki Yamamoto ◽  
Akihiro Tokuhiro ◽  
...  

2020 ◽  
Vol 64 (2) ◽  
pp. 325-336 ◽  
Author(s):  
Dimitriya H. Garvanska ◽  
Jakob Nilsson

Abstract Kinetochores are instrumental for accurate chromosome segregation by binding to microtubules in order to move chromosomes and by delaying anaphase onset through the spindle assembly checkpoint (SAC). Dynamic phosphorylation of kinetochore components is key to control these activities and is tightly regulated by temporal and spatial recruitment of kinases and phosphoprotein phosphatases (PPPs). Here we focus on PP1, PP2A-B56 and PP2A-B55, three PPPs that are important regulators of mitosis. Despite the fact that these PPPs share a very similar active site, they target unique ser/thr phosphorylation sites to control kinetochore function. Specificity is in part achieved by PPPs binding to short linear motifs (SLiMs) that guide their substrate specificity. SLiMs bind to conserved pockets on PPPs and are degenerate in nature, giving rise to a range of binding affinities. These SLiMs control the assembly of numerous substrate specifying complexes and their position and binding strength allow PPPs to target specific phosphorylation sites. In addition, the activity of PPPs is regulated by mitotic kinases and inhibitors, either directly at the activity level or through affecting PPP–SLiM interactions. Here, we discuss recent progress in understanding the regulation of PPP specificity and activity and how this controls kinetochore biology.


1997 ◽  
Vol 13 (3) ◽  
pp. 195-205 ◽  
Author(s):  
Marit Sorensen

Adherence to lifestyle changes - beginning to exercise, for example - is assumed to be mediated by self-referent thoughts. This paper describes a pilot study and three studies conducted to develop and validate a questionnaire for adults to determine their self-perceptions related to health-oriented exercise. The pilot study identified items pertinent to the domains considered important in this context, and began the process of selecting items. Study 2 examined the factor structure, reduced the number of items, determined the internal consistency of the factors, and explored the discriminative validity of the questionnaire as to physical activity level and gender. Four factors with a total of 24 items were accepted, measuring mastery of exercise, body perception, social comfort/discomfort in the exercise setting, and perception of fitness. All subscales had acceptable internal consistencies. Preliminary validity was demonstrated by confirming hypothesized differences in scores as to gender, age, and physical activity level. The third study examined and demonstrated convergent validity with similar existing subscales. The fourth study examined an English-language version of the questionnaire, confirming the existence of the factors and providing preliminary psychometric evidence of the viability of the questionnaire.


2008 ◽  
Author(s):  
Mahiyar F. Nasarwanji ◽  
Victor L. Paquet ◽  
David J. Feathers ◽  
James A. Lenker

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