THE OTTAWA PLASTIC METABOLISM CAGE FOR SHEEP

A moulded fiberglass metabolism cage for sheep is described. In addition to conventional use, the cage is also suitable for metabolic studies involving trace minerals and radioisotopes and for collection of digesta from sheep equipped with re-entrant intestinal cannulas.

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Metabolic studies of marine sterols by Copepods

Planta Medica ◽

10.1055/s-0032-1320354 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

JL Giner ◽

GH Wikfors ◽

RP Hassett

Keyword(s):

Metabolic Studies

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Metabolic Studies of Vitamin K1-14C and Menadione-14C in the Normal and Hepatectomized Rats

Thrombosis and Haemostasis ◽

10.1055/s-0038-1651216 ◽

1968 ◽

Vol 19 (03/04) ◽

pp. 383-388 ◽

Cited By ~ 6

Author(s):

R Losito ◽

C. A Owen ◽

E. V Flock ◽

Keyword(s):

Enzymatic Hydrolysis ◽

Oral Anticoagulants ◽

Urinary Metabolites ◽

The Other ◽

Vitamin K1 ◽

Vitamin K3 ◽

Metabolic Studies ◽

Intact Rats

SummaryThe metabolism of vitamin K1- 14C and menadione-14C (vitamin K3-14C) was studied in normal and hepateetomized rats. After the administration of menadione, about 70% of the 14C was excreted in the urine in 24 hrs in both types of rats. Two urinary metabolites were identified by enzymatic hydrolysis: one a glucuronide and the other a sulfate of reduced menadione. Thus, the liver is not necessary for the metabolism of menadione. In the vitamin K1 studies, the intact rats excreted only 10% of the 14C and the hepatectomized rats excreted less than 0.5%. The retention of vitamin K1 may explain its superiority over menadione as an antidote for overdosages of oral anticoagulants.

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METABOLIC STUDIES WITH METHANDROSTENOLONE (17β-HYDROXY-17α-METHYL-ANDROSTA-1,4-DIEN-3-ONE) IN HUMAN SUBJECTS

Acta Endocrinologica ◽

10.1530/acta.0.0380413 ◽

1961 ◽

Vol 38 (3) ◽

pp. 413-418 ◽

Cited By ~ 10

Author(s):

S. Almqvist ◽

D. Ikkos ◽

R. Luft

Keyword(s):

Urinary Excretion ◽

Testosterone Propionate ◽

Human Subjects ◽

Calcium Retention ◽

Metabolic Studies ◽

Daily Dose

ABSTRACT The effect of graded doses (5, 10 and 25 mg/d of methandrostenolone and of 25 mg/d of testosterone propionate were compared in each of three metabolically stable adult subjects. Five mg/d of methandrostenolone induced nitrogen and calcium retention. The effects observed with larger doses of methandrostenolone (10 and 25 mg/d) were not quantitatively different from those with 5 mg/d. The nitrogen and calcium retention obtained with the daily dose of 5 mg of methandrostenolone was as great or greater than that induced by testosterone propionate (25 mg/d). Methandrostenolone induced creatinuria but had no effect on sodium and chloride balances and urinary excretion of 17-ketosteroids.

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