Expression of Cyclin-dependent Kinase Inhibitor p21(WAF1/CIP1) in Non-small Cell Lung Carcinomas: Relationship with p53 Status and Proliferative Activity

P53 Status ◽

P21 Waf1

Electron microscopy evidence that cytoplasmic localization of the p16INK4A“nuclear” cyclin-dependent kinase inhibitor (CKI) in tumor cells is specific and not an artifact. A study in non-small cell lung carcinomas

Biotechnic & Histochemistry ◽

10.1080/10520290310001659466 ◽

2004 ◽

Vol 79 (1) ◽

pp. 5-10 ◽

Cited By ~ 25

Author(s):

K Evangelou ◽

J Bramis* ◽

I Peros ◽

P Zacharatos ◽

D Dasiou-Plakida ◽

...

Keyword(s):

Electron Microscopy ◽

Tumor Cells ◽

Kinase Inhibitor ◽

Small Cell ◽

Cytoplasmic Localization ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Lung Carcinomas ◽

Phase Ib/II study of the pan-cyclin-dependent kinase inhibitor roniciclib in combination with chemotherapy in patients with extensive-disease small-cell lung cancer

Lung Cancer ◽

10.1016/j.lungcan.2018.04.022 ◽

2018 ◽

Vol 123 ◽

pp. 14-21 ◽

Cited By ~ 10

Author(s):

Byoung Chul Cho ◽

Grace K. Dy ◽

Ramaswamy Govindan ◽

Dong-Wan Kim ◽

Nathan A. Pennell ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Extensive Disease ◽

Phase Ib ◽

Molecular analysis of a family of cyclin-dependent kinase inhibitor genes (p15/MTS2/INK4b and p18INK4c) in non-small cell lung cancers

Lung Cancer ◽

10.1016/s0169-5002(96)80009-2 ◽

1996 ◽

Vol 15 (3) ◽

pp. 383 ◽

Cited By ~ 1

Keyword(s):

Molecular Analysis ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Lung Cancers ◽

Inhibitor Genes

Randomized phase 2 study of the cyclin-dependent kinase inhibitor dinaciclib (MK-7965) versus erlotinib in patients with non-small cell lung cancer

Lung Cancer ◽

10.1016/j.lungcan.2013.11.020 ◽

2014 ◽

Vol 83 (2) ◽

pp. 219-223 ◽

Cited By ~ 47

Author(s):

Joe J. Stephenson ◽

John Nemunaitis ◽

Anil A. Joy ◽

Julie C. Martin ◽

Ying-Ming Jou ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Phase 2 ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Phase 2 Study ◽

Randomized Phase 2

P-057 Expression of the cyclin-dependent kinase inhibitor p21 is linkedto regulation of RAD51 in response to etoposide treatment of small cell lung cancer cells

Lung Cancer ◽

10.1016/s0169-5002(05)80551-3 ◽

2005 ◽

Vol 49 ◽

pp. S129

Author(s):

R. Jensen ◽

M. Spang-Thomsen ◽

L. Hansen

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Cells ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Etoposide Treatment

Synergistic Anticancer Activity of Topotecan— Cyclin-Dependent Kinase Inhibitor Combinations against Drug-Resistant Small Cell Lung Cancer (SCLC) Cell Lines

Journal of Cancer Therapy ◽

10.4236/jct.2013.48a008 ◽

2013 ◽

Vol 04 (08) ◽

pp. 47-53 ◽

Cited By ~ 4

Author(s):

Gerhard Hamilton ◽

Ulrike Olszewski, Lukas Klameth ◽

Ernst Ulsperger ◽

Klaus Geissler

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Anticancer Activity ◽

Cell Lines ◽

Kinase Inhibitor ◽

Small Cell ◽

Drug Resistant ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Molecular analysis of a family of cyclin-dependent kinase inhibitor genes (p15/MTS2/INK4b andp18/INK4c) in non-small cell lung cancers

Molecular Carcinogenesis ◽

10.1002/mc.2940140406 ◽

1995 ◽

Vol 14 (4) ◽

pp. 263-268 ◽

Cited By ~ 19

Author(s):

Norihiko Kawamata ◽

Carl W. Miller ◽

H. Phillip Koeffler

Keyword(s):

Molecular Analysis ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Lung Cancers ◽

Inhibitor Genes

Potentiation of anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the cyclin-dependent kinase inhibitor P276-00 in human non-small-cell lung cancer cell lines

Lung Cancer ◽

10.1016/j.lungcan.2013.08.010 ◽

2013 ◽

Vol 82 (2) ◽

pp. 214-221 ◽

Cited By ~ 13

Author(s):

Nitesh Shirsath ◽

Maggie Rathos ◽

Umesh Chaudhari ◽

H. Sivaramakrishnan ◽

Kalpana Joshi

Keyword(s):

Lung Cancer ◽

Valproic Acid ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Lung Cancer Cell ◽

Anticancer Effect ◽

Small Cell Lung ◽

Antiepileptic Agent ◽

Potentiation of in vitro and in vivoantitumor efficacy of doxorubicin by cyclin-dependent kinase inhibitor P276-00 in human non-small cell lung cancer cells

BMC Cancer ◽

10.1186/1471-2407-13-29 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 18

Author(s):

Maggie J Rathos ◽

Harshal Khanwalkar ◽

Kavita Joshi ◽

Sonal M Manohar ◽

Kalpana S Joshi

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Cells ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Downregulation of XIAP and induction of apoptosis by the synthetic cyclin-dependent kinase inhibitor GW8510 in non-small cell lung cancer cells

Cancer Biology & Therapy ◽

10.4161/cbt.5.2.2316 ◽

2006 ◽

Vol 5 (2) ◽

pp. 165-170 ◽

Cited By ~ 12

Author(s):

Fengqin Dong ◽

Wei Guo ◽

Lidong Zhang ◽

Shuhong Wu ◽

Fuminori Teraishi ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Cells ◽

Cell Lung Cancer ◽

Kinase Inhibitor ◽

Small Cell ◽

Cyclin Dependent Kinase ◽

Small Cell Lung ◽

Induction Of Apoptosis