Efficacy of Imatinib in Patients with Platelet-Derived Growth Factor Receptor Alpha–Mutated Gastrointestinal Stromal Tumors

Growth Factor Receptor ◽

Stromal Tumors ◽

Receptor Alpha ◽

Outcome of Patients with Platelet-Derived Growth Factor Receptor Alpha–Mutated Gastrointestinal Stromal Tumors in the Tyrosine Kinase Inhibitor Era

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-11-3025 ◽

2012 ◽

Vol 18 (16) ◽

pp. 4458-4464 ◽

Cited By ~ 97

Author(s):

Philippe A. Cassier ◽

Elena Fumagalli ◽

Piotr Rutkowski ◽

Patrick Schöffski ◽

Martine Van Glabbeke ◽

...

Keyword(s):

Growth Factor ◽

Tyrosine Kinase ◽

Tyrosine Kinase Inhibitor ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Stromal Tumors ◽

Receptor Alpha ◽

Abstract 3005: Comprehensive profile of platelet derived growth factor receptor alpha (PDGFRA) mutations in gastrointestinal stromal tumors

10.1158/1538-7445.am2020-3005 ◽

2020 ◽

Author(s):

Homma Khosroyani ◽

Lillian R. Klug ◽

Ajia Town ◽

Jonas Lategahn ◽

Johanna Falkenhorst ◽

...

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Stromal Tumors ◽

Receptor Alpha ◽

Molecular and Immunohistochemical Study of Platelet Derived Growth Factor Receptor Alpha in KIT Negative Gastrointestinal Stromal Tumors; the First Report from Iran

Middle East Journal of Digestive Diseases ◽

10.15171/mejdd.2016.25 ◽

2016 ◽

Vol 8 (3) ◽

pp. 226-231

Author(s):

Bita Geramizadeh ◽

Zahra Jowkar ◽

Seyed-Javad Mousavi

Keyword(s):

Growth Factor ◽

Immunohistochemical Study ◽

Growth Factor Receptor ◽

First Report ◽

Stromal Tumors ◽

Receptor Alpha ◽

Discovery of Potent, Selective Stem Cell Factor Receptor/Platelet Derived Growth Factor Receptor Alpha (c-KIT/PDGFRα) Dual Inhibitor for the Treatment of Imatinib-Resistant Gastrointestinal Stromal Tumors (GISTs)

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.7b00468 ◽

2017 ◽

Vol 60 (12) ◽

pp. 5099-5119 ◽

Cited By ~ 6

Author(s):

Yanli Lu ◽

Fei Mao ◽

Xiaokang Li ◽

Xinyu Zheng ◽

Manjiong Wang ◽

...

Keyword(s):

Stem Cell ◽

Growth Factor ◽

Stem Cell Factor ◽

Growth Factor Receptor ◽

Dual Inhibitor ◽

Stromal Tumors ◽

Imatinib Resistant ◽

Reduced Expression Of Platelet-Derived Growth Factor Receptor-Alpha In Neonatal Lung Mesenchymal Stromal Cells From Infants Developing Bronchopulmonary Dysplasia

10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1209 ◽

2012 ◽

Author(s):

Antonia P. Popova ◽

J. K. Bentley ◽

Paul Bozyk ◽

M J. Linn ◽

Jing Lei ◽

...

Keyword(s):

Growth Factor ◽

Bronchopulmonary Dysplasia ◽

Mesenchymal Stromal Cells ◽

Stromal Cells ◽

Growth Factor Receptor ◽

Receptor Alpha ◽

Factor Receptor Alpha ◽

Neonatal Lung

Conditional deletion of platelet derived growth factor receptor alpha (Pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice

Cell Death and Differentiation ◽

10.1038/s41418-018-0216-2 ◽

2018 ◽

Vol 26 (8) ◽

pp. 1396-1410 ◽

Cited By ~ 3

Author(s):

Chen Qian ◽

Zhongluan Wu ◽

Roy Chun-Laam Ng ◽

Maria-Mercè Garcia-Barceló ◽

Zheng-Wei Yuan ◽

...

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Developmental Anomalies ◽

Receptor Alpha ◽

Conditional Deletion ◽

Olaratumab: a platelet-derived growth factor receptor-α-blocking antibody for the treatment of soft tissue sarcoma

Clinical Pharmacology Advances and Applications ◽

10.2147/cpaa.s130178 ◽

2017 ◽

Vol Volume 9 ◽

pp. 159-164

Author(s):

Alexandra Pender ◽

Robin L Jones

Keyword(s):

Growth Factor ◽

Soft Tissue ◽

Soft Tissue Sarcoma ◽

Growth Factor Receptor ◽

Blocking Antibody ◽

Receptor Alpha ◽

Alpha Blocking ◽

Implication of platelet-derived growth factor receptor alpha in prostate cancer skeletal metastasis

Chinese Journal of Cancer ◽

10.5732/cjc.011.10225 ◽

2011 ◽

Vol 30 (9) ◽

pp. 612-619 ◽

Cited By ~ 10

Author(s):

Qingxin Liu ◽

Danielle Jernigan ◽

Yun Zhang ◽

Alessandro Fatatis

Keyword(s):

Prostate Cancer ◽

Growth Factor ◽

Growth Factor Receptor ◽

Skeletal Metastasis ◽

Receptor Alpha ◽

Novel guanidine compounds inhibit platelet‐derived growth factor receptor alpha transcription and oligodendrocyte precursor cell proliferation

Glia ◽

10.1002/glia.23930 ◽

2020 ◽

Author(s):

Jelena Medved ◽

William M. Wood ◽

Michael D. Heyst ◽

Amin Sherafat ◽

Ju‐Young Song ◽

...

Keyword(s):

Cell Proliferation ◽

Growth Factor ◽

Growth Factor Receptor ◽

Precursor Cell ◽

Oligodendrocyte Precursor Cell ◽

Receptor Alpha ◽

Factor Receptor Alpha ◽

Oligodendrocyte Precursor

Gain-of-function mutations of platelet-derived growth factor receptor α gene in gastrointestinal stromal tumors

Gastroenterology ◽

10.1016/s0016-5085(03)01046-1 ◽

2003 ◽

Vol 125 (3) ◽

pp. 660-667 ◽

Cited By ~ 448

Author(s):

Seiichi Hirota ◽

Akiko Ohashi ◽

Toshirou Nishida ◽

Koji Isozaki ◽

Kazuo Kinoshita ◽

...

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Gain Of Function ◽

Stromal Tumors