Central systolic blood pressure (cSBP) to brachial systolic blood pressure (brachSBP) ratio reproducibility during antihypertensive therapy

Post-exertional malaise (PEM) is regarded as the hallmark symptom in chronic fatigue syndrome (CFS). The aim of the current study is to explore differences in CFS patients with and without PEM in indicators of aortic stiffness, autonomic nervous system function, and severity of fatigue. One-hundred and one patients met the Fukuda criteria. A Chronic Fatigue Questionnaire (CFQ) and Fatigue Impact Scale (FIS) were used to assess the level of mental and physical fatigue. Aortic systolic blood pressure (sBPaortic) and the autonomic nervous system were measured with the arteriograph and Task Force Monitor, respectively. Eighty-two patients suffered prolonged PEM according to the Fukuda criteria, while 19 did not. Patients with PEM had higher FIS scores (p = 0.02), lower central systolic blood pressure (p = 0.02) and higher mental fatigue (p = 0.03). For a one-point increase in the mental fatigue component of the CFQ scale, the risk of PEM increases by 34%. For an sBPaortic increase of 1 mmHg, the risk of PEM decreases by 5%. For a one unit increase in sympathovagal balance, the risk of PEM increases by 330%. Higher mental fatigue and sympathetic activity in rest are related to an increased risk of PEM, while higher central systolic blood pressure is related to a reduced risk of PEM. However, none of the between group differences were significant after FDR correction, and therefore conclusions should be treated with caution and replicated in further studies.

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Carotid intima-media thickness is associated with cognitive deficiency in hypertensive patients with elevated central systolic blood pressure

Cardiovascular Ultrasound ◽

10.1186/1476-7120-10-41 ◽

2012 ◽

Vol 10 (1) ◽

Cited By ~ 6

Author(s):

Eros da Mota Dias ◽

Luiz Tadeu Giollo ◽

Débora Dada Martinelli ◽

Camila Mazeti ◽

Heitor Moreno Júnior ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Intima Media Thickness ◽

Carotid Intima Media Thickness ◽

Hypertensive Patients ◽

Media Thickness ◽

Central Systolic Blood Pressure ◽

Cognitive Deficiency

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Effects of Cranberry Juice Supplementation on Cardiovascular Disease Risk Factors in Adults with Elevated Blood Pressure: A Randomized Controlled Trial

Nutrients ◽

10.3390/nu13082618 ◽

2021 ◽

Vol 13 (8) ◽

pp. 2618

Author(s):

Chesney K. Richter ◽

Ann C. Skulas-Ray ◽

Trent L. Gaugler ◽

Stacey Meily ◽

Kristina S. Petersen ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Cardiovascular Disease ◽

Systolic Blood Pressure ◽

Vascular Function ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Lipoprotein Profile ◽

Cranberry Juice ◽

Central Systolic Blood Pressure

Emerging cardiovascular disease (CVD) risk factors, including central vascular function and HDL efflux, may be modifiable with food-based interventions such as cranberry juice. A randomized, placebo-controlled, crossover trial was conducted in middle-aged adults with overweight/obesity (n = 40; mean BMI: 28.7 ± 0.8 kg/m2; mean age: 47 ± 2 years) and elevated brachial blood pressure (mean systolic/diastolic BP: 124 ± 2/81 ± 1 mm Hg). Study participants consumed 500 mL/d of cranberry juice (~16 fl oz; 27% cranberry juice) or a matched placebo juice in a randomized order (8-week supplementation periods; 8-week compliance break), with blood samples and vascular measurements obtained at study entry and following each supplementation period. There was no significant treatment effect of cranberry juice supplementation on the primary endpoint of central systolic blood pressure or central or brachial diastolic pressure. Cranberry juice significantly reduced 24-h diastolic ambulatory BP by ~2 mm Hg compared to the placebo (p = 0.05) during daytime hours. Cranberry juice supplementation did not alter LDL-C but significantly changed the composition of the lipoprotein profile compared to the placebo, increasing the concentration of large LDL-C particles (+29.5 vs. −6.7 nmol/L; p = 0.02) and LDL size (+0.073 vs. −0.068 nm; p = 0.001). There was no effect of treatment on ex vivo HDL efflux in the total population, but exploratory subgroup analyses identified an interaction between BMI and global HDL efflux (p = 0.02), with greater effect of cranberry juice in participants who were overweight. Exploratory analyses indicate that baseline C-reactive protein (CRP) values may moderate treatment effects. In this population of adults with elevated blood pressure, cranberry juice supplementation had no significant effect on central systolic blood pressure but did have modest effects on 24-hr diastolic ambulatory BP and the lipoprotein profile. Future studies are needed to verify these findings and the results of our exploratory analyses related to baseline health moderators.

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EFFECT OF SEQUENTIAL NEPHRON BLOCKING IN COMPARISON WITH THE DOUBLE BLOCKADE OF THE RENIN- ANGIOTENSIN SYSTEM + BISOPROLOL ON CENTRAL SYSTOLIC BLOOD PRESSURE AND ARTERIAL STIFFNESS

Journal of Hypertension ◽

10.1097/01.hjh.0000748620.90653.e8 ◽

2021 ◽

Vol 39 (Supplement 1) ◽

pp. e354

Author(s):

Elizabeth do Espirito Santo Cestari ◽

Priscilla Galisteu de Mello ◽

Tatiane de Azevedo Rubio ◽

Maira Regina de Souza ◽

Eliangela Gianini Gonzales ◽

...

Keyword(s):

Blood Pressure ◽

Arterial Stiffness ◽

Systolic Blood Pressure ◽

Renin Angiotensin System ◽

Angiotensin System ◽

Renin Angiotensin ◽

Central Systolic Blood Pressure

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The detection rates of inter-arm systolic blood pressure difference vary with blood pressure levels in hypertensive patients under antihypertensive therapy

International Journal of Cardiology ◽

10.1016/j.ijcard.2013.12.252 ◽

2014 ◽

Vol 172 (3) ◽

pp. e419-e420 ◽

Cited By ~ 13

Author(s):

Hanjun Sun ◽

Ping Li ◽

Hai Su ◽

Jiwei Wang ◽

Weitong Hu ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Antihypertensive Therapy ◽

Pressure Difference ◽

Detection Rates ◽

Hypertensive Patients ◽

Blood Pressure Difference

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Acute effects of resistance exercise on arterial compliance

Journal of Applied Physiology ◽

10.1152/japplphysiol.00002.2005 ◽

2005 ◽

Vol 98 (6) ◽

pp. 2287-2291 ◽

Cited By ~ 103

Author(s):

Allison E. DeVan ◽

Maria M. Anton ◽

Jill N. Cook ◽

Daria B. Neidre ◽

Miriam Y. Cortez-Cooper ◽

...

Keyword(s):

Blood Pressure ◽

Resistance Training ◽

Resistance Exercise ◽

Systolic Blood Pressure ◽

Arterial Compliance ◽

Applanation Tonometry ◽

Stiffness Index ◽

Sham Control ◽

Experimental Conditions ◽

Brachial Systolic Blood Pressure

Decreased central arterial compliance is an emerging risk factor for cardiovascular disease. Resistance training is associated with reductions in the elastic properties of central arteries. Currently, it is not known whether this reduction is from one bout of resistance exercise or from an adaptation to multiple bouts of resistance training. Sixteen healthy sedentary or recreationally active adults (11 men and 5 women, age 27 ± 1 yr) were studied under parallel experimental conditions on 2 separate days. The order of experiments was randomized between resistance exercise (9 resistance exercises at 75% of 1 repetition maximum) and sham control (seated rest in the exercise room). Baseline hemodynamic values were not different between the two experimental conditions. Carotid arterial compliance (via simultaneous B-mode ultrasound and applanation tonometry) decreased and β-stiffness index increased ( P < 0.01) immediately and 30 min after resistance exercise. Immediately after resistance exercise, carotid systolic blood pressure increased ( P < 0.01), although no changes were observed in brachial systolic blood pressure at any time points. These measures returned to baseline values within 60 min after the completion of resistance exercise. No significant changes in these variables were observed during the sham control condition. These results indicate that one bout of resistance exercise acutely decreases central arterial compliance, but this effect is sustained for <60 min after the completion of resistance exercise.

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