scholarly journals Partial prostate re-irradiation for the treatment of isolated local recurrence of prostate cancer in patients previously treated with primary external beam radiotherapy: short-term results of a monocentric study

Neoplasma ◽  
2020 ◽  
Author(s):  
Fabio Matrone ◽  
Alberto Revelant ◽  
Giuseppe Fanetti ◽  
Jerry Polesel ◽  
Paola Chiovati ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Local Recurrence ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Short Term ◽  
Previously Treated ◽  
Isolated Local Recurrence

scholarly journals MULTIPARAMETRIC MRI IN PATIENTS WITH LOCALIZED PROSTATE CANCER AFTER RADICAL EXTERNAL RADIOTHERAPY

2019 ◽  
pp. 32-41
Author(s):  
M. V. Krupina ◽  
T. N. Trofimova ◽  
M. Y. Valkov
Keyword(s):  
Prostate Cancer ◽  
Local Recurrence ◽  
Current Knowledge ◽  
External Beam Radiotherapy ◽  
Locally Advanced ◽  
Local Relapse ◽  
Multiparametric Mri ◽  
Imaging Method ◽  
External Beam ◽  
Local Progression

Prostate cancer (PC) is the one of the most common and socially significant malignancies in men. Radiotherapy is currently one of the leading conservative special treatments for a localized and locally advanced PC. The frequency of biochemical recurrence after external beam radiotherapy (EBRT) is high. One of the main problems is a differentiation between local and systemic relapse of PC. Nevertheless, a local recurrence of PC after radiotherapy can occur without increasing PSA. Magnetic resonance imaging (MRI) is a highly informative imaging method, however, currently it is used mostly for the primary diagnosis and is not included into the recommendations for detecting recurrent prostate cancer after treatment. MR-pattern of the local progression after radical EBRT can be similar to that of primary PC. It is also difficult to diagnose local relapse of prostate cancer in some cases. Multiparametric MRI (mpMRI) has the greatest prospects in the diagnosis of local tumor recurrence in prostate cancer patients after radical external beam radiotherapy. The article provides an overview of domestic and foreign literature, in which we attempted to systematize current knowledge about the possibilities of the mpMRI in diagnosing local recurrence after radical EBRT and, based on the results of published studies, identify directions for further application of this approach.

Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high-intensity focused ultrasonography

Urology ◽  
2004 ◽  
Vol 63 (4) ◽  
pp. 625-629 ◽  
Author(s):  
Albert Gelet ◽  
Jean Yves Chapelon ◽  
Laura Poissonnier ◽  
Raymonde Bouvier ◽  
Olivier Rouvière ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Local Recurrence ◽  
Salvage Therapy ◽  
High Intensity ◽  
External Beam Radiotherapy ◽  
Early Experience ◽  
External Beam

scholarly journals Salvage Brachytherapy for Castration-Resistant and External Beam Radiotherapy-Resistant Local Recurrence 17 Years after Radical Prostatectomy

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Shogo Hosogoe ◽  
Osamu Soma ◽  
Teppei Matsumoto ◽  
Atsushi Imai ◽  
Shingo Hatakeyama ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Local Recurrence ◽  
Ct Scan ◽  
External Beam Radiotherapy ◽  
External Beam Radiation ◽  
External Beam ◽  
Beam Radiation ◽  
Old Japanese ◽  
Salvage Brachytherapy

A 47-year-old Japanese man was diagnosed with prostate cancer in February 1995 (Initial PSA 77.2 ng/mL, GS3 + 4, cT3N0M0). He underwent radical prostatectomy after androgen deprivation therapy (ADT) in June 1995. Nine years after operation, he was diagnosed with local recurrence of prostate cancer and he received postoperative external beam radiation therapy (EBRT) (70 Gy). By May 2008, the PSA dropped to 0.33 ng/mL, and a CT scan showed that the mass had disappeared. On April 2012, the PSA once again rose to 3.1 ng/mL. CT scan and MRI revealed a mass in the prostatic bed. We diagnosed local recurrence of prostate cancer. We underwent salvage low-dose brachytherapy after obtaining informed consent. The prescribed dose of the salvage brachytherapy was 145 Gy to control the tumor considering the hormone resistant prostatic cancer and high-risk feature. PSA level rapidly decreased to 0.66 ng/mL by 6 months after seed implantation. No adverse events were seen during the follow-up period.

Sign in / Sign up

Export Citation Format

Share Document