Liposomal drug delivery systems for targeted cancer therapy: is active targeting the best choice?

2016 ◽  
Vol 8 (17) ◽  
pp. 2091-2112 ◽  
Author(s):  
Shaghayegh Fathi ◽  
Adegboyega K Oyelere
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Active Targeting ◽  
Targeted Cancer Therapy ◽  
Liposomal Drug ◽  
Liposomal Drug Delivery

Liposomal Drug Delivery Systems for Cancer Therapy

2003 ◽  
pp. 191-214 ◽  
Author(s):  
Daryl C. Drummond ◽  
Dmitri Kirpotin ◽  
Christopher C. Benz ◽  
John W. Park ◽  
Keelung Hong
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Liposomal Drug ◽  
Liposomal Drug Delivery

scholarly journals Liposomal Formulations In Cancer Therapy: Passive Versus Active Targeting

2019 ◽  
Vol 7 (2) ◽  
pp. 35-38
Author(s):  
Tosha Pandya ◽  
Kaushika Kaushika Patel ◽  
Rudree Pathak ◽  
Shreeraj Shah
Keyword(s):  
Drug Delivery ◽  
Cancer Treatment ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Active Targeting ◽  
Liposomal Drug ◽  
Passive Targeting ◽  
Liposomal Formulations ◽  
Nano Drug Delivery ◽  
Liposomal Drug Delivery

In Cancer therapy, Nano drug delivery system comprising of Liposomes, are the most successful mode of treatment in present scenario which also has real time clinical application. Recently it is found that the closed bilayer phospholipid vesicles have many technical advantages over the initially used liposomal formulations. The delivery of therapeutics encapsulated in liposomes changes the biological distribution profile and improves the drug therapeutic indices of various drugs. This review article throws light onto many clinical liposomal drug delivery products. The liposome Nano drug delivery by the active and passive targeting is a boon as it can reduce the off-targeting effects. The current development is more focused on the diagnostic and clinical applications. Receptor targeted delivery systems are extensively explored for active targeting. However, these delivery systems are rarely seen in the clinical application because of conjugation chemistry and other implicit hurdles to develop this system.The development of nanocarriers in the cancer treatment have enormous potential in the medical field. Moreover, Immuno liposomes have been used in cancer treatment as attractive drug targeting vehicles. On the other hand, there are many other liposomal drug delivery systems having passive targeting mechanism for cancer treatment which are widely used due to enhanced retention and permeability of formulation. This review majorly focuses on the current challenges encountered in development of liposomal Nano drug delivery systems and its effective development for cancer treatment.

Photo-triggerable liposomal drug delivery systems: from simple porphyrin insertion in the lipid bilayer towards supramolecular assemblies of lipid–porphyrin conjugates

2019 ◽  
Vol 7 (11) ◽  
pp. 1805-1823 ◽  
Author(s):  
Julien Massiot ◽  
Véronique Rosilio ◽  
Ali Makky
Keyword(s):  
Drug Delivery ◽  
Lipid Bilayer ◽  
Drug Delivery Systems ◽  
Active Pharmaceutical Ingredient ◽  
Delivery Systems ◽  
Supramolecular Assemblies ◽  
Liposomal Drug ◽  
Spatio Temporal ◽  
Nanoparticulate Systems ◽  
Liposomal Drug Delivery

Light-responsive liposomes are considered nowadays as one of the most promising nanoparticulate systems for the delivery and release of an active pharmaceutical ingredient (API) in a spatio-temporal manner.

Phototriggering of liposomal drug delivery systems

2001 ◽  
Vol 53 (3) ◽  
pp. 273-284 ◽  
Author(s):  
Pochi Shum ◽  
Jong-Mok Kim ◽  
David H Thompson
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Liposomal Drug ◽  
Liposomal Drug Delivery
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