FASTING BLOOD GLUCOSE LEVELS AND INITIATION OF INSULIN THERAPY IN GESTATIONAL DIABETES

1996 ◽  
Vol 2 (5) ◽  
pp. 330-332 ◽  
Author(s):  
Jason Laird, MD ◽  
Kay F. McFarland, MD, FACE
Author(s):  
Coskun Simsir ◽  
Muberra Namli Kalem ◽  
Ziya Kalem ◽  
Turgut Var ◽  
Batuhan Bakirarar ◽  
...  

Background: Several previous studies suggest that SPX plays a role in appetite control and body weight and blood glucose regulation. The aim of this study to determine SPX levels in healthy pregnancies and in gestational diabetes (GDM) and to investigate the association of SPX levels with weight gain and lipid and glucose metabolism in subjects with and without GDM.Methods: A total of 44 women with GDM and 44 women without GDM were randomly enrolled who applied for GDM screening during the 24-28th week of pregnancy. Demographics, blood glucose and lipid profiles and Spexin levels were compared between groups.Results: The mean age, BMI, and weight gain during pregnancy were higher in the GDM group. The LDL cholesterol, Hba1c, SPX and glucose levels in response to OGTT were higher in the GDM group. The SPX levels were correlated with Hba1c and blood glucose levels after OGTT, and were not correlated with the age, BMI, weight gain during pregnancy, lipid parameters, and fasting blood glucose levels in the whole study population.Conclusions: SPX levels were higher in the GDM group compared with non-GDM group and SPX levels were correlated with HbA1c levels and post-OGTT glucose levels but not with fasting glucose levels.


2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Dhyana Putri

AbstractBackground Gestational diabetes mellitus (GDM) was a condition of glucose intolerance that occur during pregnancy detected by examining blood glucose levels. Objective This study aims to measure fasting blood glucose levels at the second and third trimesters pregnant women in  Puskesmas I Denpasar Selatan-based on certain characteristics. Methods The type of this study is descriptive and using simple random sampling technique. Samples in this study amounted to 33 women. Blood glucose levels measured by venous blood samples with hexokinase method. Result The study results obtained 28 women (84,85%) in the not risk of GDM category and five women (15,15%) in the risk of GDM category. High blood glucose levels obtained four women (12,12%) in the category 25 years and one women (3,03%) in the category 25, on the characteristics of the gestational age obtain two women (6,06%) in the second trimester and three women (9,09%) in the third trimester, on the characteristics of DM in the family obtained one women (3,03%) with a history of DM.Conclusion  The conclusion of this research obtained fasting blood glucose level in trimester II and III pregnant women at Puskesmas I Denpasar Selatan ranged between 66 - 120 mg/dL. Keywords: blood glucose, pregnant women, gestational diabetes 


Author(s):  
Nina Meloncelli ◽  
Shelley A. Wilkinson ◽  
Susan de Jersey

AbstractGestational diabetes mellitus (GDM) is a common pregnancy disorder and the incidence is increasing worldwide. GDM is associated with adverse maternal outcomes which may be reduced with proper management. Lifestyle modification in the form of medical nutrition therapy and physical activity, as well as self-monitoring of blood glucose levels, is the cornerstone of GDM management. Inevitably, the search for the “ultimate” diet prescription has been ongoing. Identifying the amount and type of carbohydrate to maintain blood glucose levels below targets while balancing the nutritional requirements of pregnancy and achieving gestational weight gain within recommendations is challenging. Recent developments in the area of the gut microbiota and its impact on glycemic response add another layer of complexity to the success of medical nutrition therapy. This review critically explores the challenges to dietary prescription for GDM and why utopia may never be found.


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