scholarly journals PWT-458, a novel pegylated-17-hydroxywortmannin, inhibits phosphatidylinositol 3-kinase signaling and suppresses growth of solid tumors

2005 ◽  
Vol 4 (5) ◽  
pp. 538-545 ◽  
Author(s):  
Ker Yu ◽  
Judy Lucas ◽  
Tianmin Zhu ◽  
Arie Zask ◽  
Christine Gaydos ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Kinase Signaling ◽  
Phosphatidylinositol 3 Kinase ◽  
Phosphatidylinositol 3

scholarly journals Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities

Cancer ◽  
2018 ◽  
Vol 125 (7) ◽  
pp. 1185-1199 ◽  
Author(s):  
Sherri Z. Millis ◽  
Denis L. Jardim ◽  
Lee Albacker ◽  
Jeffrey S. Ross ◽  
Vincent A. Miller ◽  
...  
Keyword(s):  
Targeted Therapy ◽  
Solid Tumors ◽  
Phosphatidylinositol 3 Kinase ◽  
Genomic Alterations ◽  
Kinase Pathway ◽  
Phosphatidylinositol 3

Targeting phosphatidylinositol 3-kinase signaling in acute myelogenous leukemia

2013 ◽  
Vol 17 (8) ◽  
pp. 921-936 ◽  
Author(s):  
Camilla Evangelisti ◽  
Cecilia Evangelisti ◽  
Daniela Bressanin ◽  
Francesca Buontempo ◽  
Francesca Chiarini ◽  
...  
Keyword(s):  
Acute Myelogenous Leukemia ◽  
Myelogenous Leukemia ◽  
Kinase Signaling ◽  
Phosphatidylinositol 3 Kinase ◽  
Acute Myelogenous ◽  
Phosphatidylinositol 3

scholarly journals Modulation of phosphatidylinositol 3-kinase signaling reduces intimal hyperplasia in aortocoronary saphenous vein grafts

2005 ◽  
Vol 129 (6) ◽  
pp. 1405-1413 ◽  
Author(s):  
Jonathan A. Hata ◽  
Jason A. Petrofski ◽  
Jacob N. Schroder ◽  
Matthew L. Williams ◽  
Sarah H. Timberlake ◽  
...  
Keyword(s):  
Saphenous Vein ◽  
Intimal Hyperplasia ◽  
Kinase Signaling ◽  
Phosphatidylinositol 3 Kinase ◽  
Vein Grafts ◽  
Saphenous Vein Grafts ◽  
Phosphatidylinositol 3

scholarly journals Decreased L-Type Ca2+ Current in Cardiac Myocytes of Type 1 Diabetic Akita Mice Due to Reduced Phosphatidylinositol 3-Kinase Signaling

Diabetes ◽  
2007 ◽  
Vol 56 (11) ◽  
pp. 2780-2789 ◽  
Author(s):  
Z. Lu ◽  
Y.-P. Jiang ◽  
X.-H. Xu ◽  
L. M. Ballou ◽  
I. S. Cohen ◽  
...  
Keyword(s):  
Cardiac Myocytes ◽  
Kinase Signaling ◽  
Phosphatidylinositol 3 Kinase ◽  
Akita Mice ◽  
Phosphatidylinositol 3

scholarly journals Localization of Fas/CD95 into the Lipid Rafts on Down-Modulation of the Phosphatidylinositol 3-Kinase Signaling Pathway

2008 ◽  
Vol 6 (4) ◽  
pp. 604-613 ◽  
Author(s):  
Marie Bénéteau ◽  
Mathieu Pizon ◽  
Benjamin Chaigne-Delalande ◽  
Sophie Daburon ◽  
Patrick Moreau ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Lipid Rafts ◽  
Kinase Signaling ◽  
Phosphatidylinositol 3 Kinase ◽  
Kinase Signaling Pathway ◽  
Phosphatidylinositol 3
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