scholarly journals The PERK-eIF2α phosphorylation arm is a pro-survival pathway of BCR-ABL signaling and confers resistance to imatinib treatment in chronic myeloid leukemia cells

Cell Cycle ◽  
2012 ◽  
Vol 11 (21) ◽  
pp. 4069-4078 ◽  
Author(s):  
Monika Kusio-Kobialka ◽  
Paulina Podszywalow-Bartnicka ◽  
Philippos Peidis ◽  
Eliza Glodkowska-Mrowka ◽  
Kamila Wolanin ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Imatinib Treatment ◽  
Eif2α Phosphorylation ◽  
Survival Pathway

scholarly journals A novel HDAC inhibitor chidamide combined with imatinib synergistically targets tyrosine kinase inhibitor resistant chronic myeloid leukemia cells

2020 ◽  
Vol 129 ◽  
pp. 110390
Author(s):  
Bailin He ◽  
Qiang Wang ◽  
Xiaoli Liu ◽  
Ziyuan Lu ◽  
Jiaochan Han ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Tyrosine Kinase ◽  
Tyrosine Kinase Inhibitor ◽  
Hdac Inhibitor ◽  
Myeloid Leukemia ◽  
Kinase Inhibitor ◽  
Leukemia Cells

scholarly journals ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine model

2015 ◽  
Vol 137 (3) ◽  
pp. 698-709 ◽  
Author(s):  
Rihab R. Nasr ◽  
Raed A. Hmadi ◽  
Rabab M. El-Eit ◽  
Ahmad N. Iskandarani ◽  
Mark N. Jabbour ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Murine Model ◽  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Synthetic Retinoid ◽  
Orally Active

Targeting HSPA8 inhibits proliferation via downregulating BCR-ABL and enhances chemosensitivity in imatinib-resistant chronic myeloid leukemia cells

2021 ◽  
pp. 112708
Author(s):  
Zhen Liu ◽  
Wenlong Zheng ◽  
Yuan Liu ◽  
Binghe Zhou ◽  
Yuqing Zhang ◽  
...  
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Imatinib Resistant

Tyrosine-phosphorylated STAT5 accumulates on podosomes in Hck-transformed fibroblasts and chronic myeloid leukemia cells

2007 ◽  
Vol 213 (1) ◽  
pp. 212-220 ◽  
Author(s):  
Renaud Poincloux ◽  
Céline Cougoule ◽  
Thomas Daubon ◽  
Isabelle Maridonneau-Parini ◽  
Véronique Le Cabec
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Transformed Fibroblasts

Transcriptional activation of Skp2 by BCR-ABL in K562 chronic myeloid leukemia cells

2009 ◽  
Vol 33 (11) ◽  
pp. 1520-1524 ◽  
Author(s):  
Jing-Yi Chen ◽  
Ming-Chung Wang ◽  
Wen-Chun Hung
Keyword(s):  
Chronic Myeloid Leukemia ◽  
Transcriptional Activation ◽  
Myeloid Leukemia ◽  
Leukemia Cells

Knock-down of CIAPIN1 sensitizes K562 chronic myeloid leukemia cells to Imatinib by regulation of cell cycle and apoptosis-associated members via NF-κB and ERK5 signaling pathway

2016 ◽  
Vol 99 ◽  
pp. 132-145 ◽  
Author(s):  
Jian Wang ◽  
Qinghua Li ◽  
Chijuan Wang ◽  
Qingqing Xiong ◽  
Yani Lin ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Chronic Myeloid Leukemia ◽  
Signaling Pathway ◽  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Knock Down ◽  
Regulation Of Cell Cycle
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