scholarly journals Regulatory role of indeterminate domain 10 (IDD10) in ammonium-dependent gene expression in rice roots

2013 ◽  
Vol 8 (5) ◽  
pp. e24139 ◽  
Author(s):  
Yuan Hu Xuan ◽  
Ryza A. Priatama ◽  
Vikranth Kumar ◽  
Chang-deok Han
Keyword(s):  
Gene Expression ◽  
Regulatory Role ◽  
Rice Roots

Gene expression profiles predict the possible regulatory role of OPN-mediated signaling pathways in rat liver regeneration

Gene ◽  
2016 ◽  
Vol 576 (2) ◽  
pp. 782-790 ◽  
Author(s):  
Gaiping Wang ◽  
Shasha Chen ◽  
Congcong Zhao ◽  
Xiaofang Li ◽  
Ling Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Liver Regeneration ◽  
Signaling Pathways ◽  
Rat Liver ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Regulatory Role ◽  
Rat Liver Regeneration

scholarly journals Potential Roles for G-Quadruplexes in Mitochondria

2019 ◽  
Vol 26 (16) ◽  
pp. 2918-2932 ◽  
Author(s):  
Micol Falabella ◽  
Rafael J. Fernandez ◽  
F. Brad Johnson ◽  
Brett A. Kaufman
Keyword(s):  
Gene Expression ◽  
Mitochondrial Genome ◽  
Mitochondrial Function ◽  
Genome Instability ◽  
Nuclear Genome ◽  
Short Review ◽  
Regulatory Role ◽  
Rna Sequences ◽  
Mtdna Deletions

Some DNA or RNA sequences rich in guanine (G) nucleotides can adopt noncanonical conformations known as G-quadruplexes (G4). In the nuclear genome, G4 motifs have been associated with genome instability and gene expression defects, but they are increasingly recognized to be regulatory structures. Recent studies have revealed that G4 structures can form in the mitochondrial genome (mtDNA) and potential G4 forming sequences are associated with the origin of mtDNA deletions. However, little is known about the regulatory role of G4 structures in mitochondria. In this short review, we will explore the potential for G4 structures to regulate mitochondrial function, based on evidence from the nucleus.

scholarly journals Identification of regulatory role of DNA methylation in colon cancer gene expression via systematic bioinformatics analysis

Medicine ◽  
2017 ◽  
Vol 96 (47) ◽  
pp. e8487 ◽  
Author(s):  
Yong Yang ◽  
Fu-Hao Chu ◽  
Wei-Ru Xu ◽  
Jia-Qi Sun ◽  
Xu Sun ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Colon Cancer ◽  
Bioinformatics Analysis ◽  
Regulatory Role ◽  
Cancer Gene

scholarly journals Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers

2013 ◽  
Vol 17 (01) ◽  
pp. 23-32 ◽  
Author(s):  
Juan Pablo Lopez ◽  
Laura M. Fiori ◽  
Jeffrey A. Gross ◽  
Benoit Labonte ◽  
Volodymyr Yerko ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prefrontal Cortex ◽  
Regulatory Role ◽  
Suicide Completers

scholarly journals CRZ1 regulator and calcium cooperatively modulate holocellulases gene expression in Trichoderma reesei QM6a

2019 ◽  
Author(s):  
Leonardo Martins-Santana ◽  
Renato Graciano de Paula ◽  
Adriano Gomes Silva ◽  
Douglas Christian Borges Lopes ◽  
Roberto do Nascimento Silva ◽  
...  
Keyword(s):  
Gene Expression ◽  
Trichoderma Reesei ◽  
Regulatory Network ◽  
Plant Biomass ◽  
Transcriptional Regulators ◽  
Regulatory Role ◽  
Cellulolytic Enzymes ◽  
Strong Increase ◽  
New Evidence

AbstractBackgroundTrichoderma reesei is the main filamentous fungus used in industry to produce cellulases. Over the last decades, there have been a strong increase in the understanding of the regulatory network controlling cellulase-coding gene expression in response to a number of inducers and environmental signals. In this sense, the role of calcium and the Calcineurin-responsive protein (CRZ1) has been investigated in industrially relevant strains of T. reesei RUT-C30, but this system has not been investigated in wild-type reference strain of this fungus.ResultsHere, we investigated the role of CRZ1 and Ca2+ signaling in the fungus T. reesei QM6a. For this, we first searched for potential CRZ1 binding sites in promoter regions of key genes coding holocellulases, as well as transcriptional regulators and sugar and calcium transporters. Using a nearly constructed T. reesei Δcrzl strain, we demonstrated that most of the genes expected to be regulated by CRZ1 were affected in the mutant strain induced with sugarcane bagasse (SCB) and cellulose. In particular, our data demonstrate that Ca2+ acts synergistically with CRZ1 to modulate gene expression, but also exerts CRZ1-independent regulatory role in gene expression in T. reesei, suggesting the existence of additional Ca2+ sensing mechanisms in this fungus.ConclusionsThis work presents new evidence on the regulatory role of CRZ1 and Ca2+ sensing in the regulation of cellulolytic enzymes in T. reesei, evidencing significant and previously unknown function of this Ca2+ sensing system in the control key transcriptional regulators (XYR1 and CRE1) and on the expression of genes related to sugar and Ca2+ transport. Taken together, the data obtained here provide new evidence on the regulatory network of T. reesei related to plant biomass deconstruction.

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