Ocular Pharmacokinetics of Antiviral Nanoformulations by Ultra High-pressure Liquid Chromatographic Method

2010 ◽  
Vol 01 (01) ◽  
Author(s):  
Sohail Akhter ◽  
Gaurav K Jain ◽  
Shadab A Pathan ◽  
Musarrat H. Warsi ◽  
Prakash Chander
Keyword(s):  
High Pressure ◽  
Chromatographic Method ◽  
Ocular Pharmacokinetics ◽  
High Pressure Liquid Chromatographic ◽  
Ultra High Pressure ◽  
Liquid Chromatographic Method ◽  
Liquid Chromatographic

Determination of Uncombined Intermediates in FD&C Yellow No. 6 by High-Pressure Liquid Chromatography

1974 ◽  
Vol 57 (2) ◽  
pp. 358-359
Author(s):  
Manjeet Singh
Keyword(s):  
High Pressure ◽  
Chromatographic Method ◽  
Sulfanilic Acid ◽  
Sunset Yellow ◽  
High Pressure Liquid Chromatographic ◽  
Liquid Chromatographic Method ◽  
Two Samples ◽  
Liquid Chromatographic ◽  
Good Agreement

Abstract A high-pressure liquid chromatographic method is presented for the isolation and determination of uncombined intermediates in FD&C Yellow No. 6 (sunset yellow FCF, CI. No. 15895). Samples of FD&C Yellow No. 6 containing 0.1-0.4% sulfanilic acid, 0.1-0.4% 6-hydroxy-2-naphthalenesulfonic acid, and 0.3— 1.0% 6,6'-oxybis(2-naphthalenesulfonic acid) were prepared and analyzed using this method. Recoveries ranged between 94 and 101%. Twenty-two samples of FD&C Yellow No. 6 were analyzed by the conventional column elution chromatographic method as well as by the high-pressure liquid chromatographic method. Good agreement was obtained between the 2 methods.

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