Hilar Lymph Node Involvement in Colorectal Cancer Liver Metastases ? An Overview

2011 ◽  
Vol s6 ◽  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Liver Metastases ◽  
Lymph Node Involvement ◽  
Colorectal Cancer Liver Metastases ◽  
Hilar Lymph Node ◽  
Node Involvement

Hepatic lymph node involvement in resected cases of liver metastases from colorectal cancer

1999 ◽  
Vol 42 (10) ◽  
pp. 1285-1290 ◽  
Author(s):  
Norihiro Kokudo ◽  
Tadao Sato ◽  
Makoto Seki ◽  
Hirotoshi Ohta ◽  
Kaoru Azekura ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Liver Metastases ◽  
Lymph Node Involvement ◽  
Node Involvement ◽  
Hepatic Lymph Node

scholarly journals Colorectal Cancer Presenting as Single Pulmonary Hilar Lymph Node Metastasis

2018 ◽  
Vol 2018 ◽  
pp. 1-3
Author(s):  
Ahmed M. Habib ◽  
Xenophon Kassianides ◽  
Samuel Chan ◽  
Mahmoud Loubani ◽  
Syed Qadri
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Mediastinal Lymph Node ◽  
Lymph Node Involvement ◽  
Pulmonary Metastasectomy ◽  
Hilar Lymph Node ◽  
Node Metastasis ◽  
Mediastinal Metastasis ◽  
Node Involvement ◽  
Hilar Lymph Node Metastasis

Colorectal carcinoma is the second biggest cancer responsible for mortality. Lung metastasis is the commonest, following the liver. It is not uncommon to perform pulmonary metastasectomy and identify mediastinal metastasis. Previous studies have identified incidental lymph node involvement following routine mediastinal lymph node clearance in 20–50% of cases. However, solitary intrathoracic lymph node metastasis is exceedingly rare. Even when present, it is usually metachronous. In our case, we present an exceedingly rare case whereby the intrathoracic lymph node metastasis is solitary, not accompanying pulmonary disease and with no liver metastasis. We also review the evidence for mediastinal lymphadenectomy in the literature.

Optimizing cut-offs for high neutrophil-to-lymphocyte ratio as poor survival prognostic factor in colorectal cancer.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e15111-e15111
Author(s):  
Fernando Namuche ◽  
Jorge Leon ◽  
Paola Catherine Montenegro ◽  
Claudio J. Flores
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Prognostic Factor ◽  
Cox Regression ◽  
Locally Advanced ◽  
Lymph Node Involvement ◽  
Histologic Grade ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Node Involvement

e15111 Background: The incidence of colorectal cancer (CRC) in Peru has increased in the last decades. Needing to use all the possible tools for an accurate diagnosis and early treatment. Neutrophil-to-lymphocyte ratio (NLR) has been associated as poor prognostic factor in OS and PFS in CRC. There is no data that support this statement in Latin America. It is of a special utility in our country the detection of a simple and reproducible prognostic biomarker that guides the use of more advanced tests. Our objective was to explore the factors associated with OS in the local-locally advanced and metastatic settings. Methods: We retrospectively reviewed the electronic medical records of 609 patients with CRC from one specialized Peruvian cancer center between 2006 and 2016 Descriptive results for numeric variables were presented as means with standard deviation (SD) or medians with interquartile range (IQR), depending on their distributions; otherwise, we expressed the qualitative variables as numbers with percentages. We divided our population into two groups: Local-locally advanced (L-LA) (516 pts) and debut metastatic- recurrence (M-R) (108 pts). We performed a ROC curve analysis to determine an appropriate cut-off value for NLR in both groups (L-LA:NLR ≥3, M-R:NLR ≥5). A univariate survival analysis was performed with Kaplan Meier method, comparing the curves with Log Rank test. A multivariate analysis was performed using the Cox regression model with the statistically significant variables found in the univariate analysis. Results: Pts with high NLR had significantly shorter OS in L-LA [HR, 12.1; 95% CI,5.019-29.211; p < 0.001] M-R [HR, 5.382; 95% CI,2.835-10.217; p < 0.001] than pts with low NLR. In the multivariate model, NLR retained a significant association with OS in both groups. Cox regression demonstrated that in L-LA setting sex, histologic grade and lymph node involvement; and in M-R setting sidedness, histologic grade, LVI and metastasectomy performed were independently risk factors for a shorter OS. Conclusions: High NLR is associated with poor prognosis (with our cut-offs L-LA:NLR ≥3, M-R:NLR ≥5). There are other variables to be considered that affect the OS, as: sex, histologic grade and lymph node involvement, sidedness, histologic grade, LVI and metastasectomy performed.

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