scholarly journals Burden of Adenovirus, Astrovirus, Norovirus and Rotavirus Gastroenteritis in Egyptian Children during 2000-2017

2018 ◽  
Vol 07 (03) ◽  
Author(s):  
Mohamed NF Shaheen
Keyword(s):  
Rotavirus Gastroenteritis ◽  
Egyptian Children

scholarly journals ABO blood grouping in Egyptian children with rotavirus gastroenteritis

2017 ◽  
Vol 3 ◽  
pp. 175-180 ◽  
Author(s):  
Hala Gouda Elnady ◽  
Ola M. Abdel Samie ◽  
Maysa Tawhid Saleh ◽  
Lobna S. Sherif ◽  
Naglaa Abdalmoneam ◽  
...  
Keyword(s):  
Rotavirus Gastroenteritis ◽  
Egyptian Children ◽  
Abo Blood Grouping ◽  
Blood Grouping

Updates in the Prevalence of Rotavirus Gastroenteritis in Babylon City

2018 ◽  
pp. 1-12
Keyword(s):  
Health Care Providers ◽  
Rural Areas ◽  
Causative Organism ◽  
Care Providers ◽  
Sample Collection ◽  
Rotavirus Infection ◽  
Rotavirus Gastroenteritis ◽  
Age Range ◽  
Latex Test ◽  
Children Under 5

Background: Diarrhea is a main cause of morbidity and mortality in children under 5 years old. Globally it is responsible for approximately four billion cases and three million deaths annually. In developing countries, it causes two million deaths each year. The major causative organism is rotavirus which is responsible for one-third of hospitalizations with approximately 40% mortality. Objectives: To determine the prevalence and demographic characteristics of rotavirus infection in Babylon city, Iraq. Materials and Methods: Fecal samples were taken from children with age range of 6 months to 5 years complained of diarrhea during the period beginning in October 2016 till August 2017. The age, gender, residence, the type of feeding, place of the sample collection and duration of diarrhea were recorded. Specimens were analyzed by Latex test for detection of rotavirus. Results: A total of 349 children presented with diarrhea, the rotavirus antigen was detected in 169 fecal specimens from children with diarrhea (48%). More percentages of positive rotavirus specimens were seen in the 5year of age. No gender differences were observed, meanwhile samples obtained from rural areas and breastfed children showed less rotavirus positive infection. Conclusion: The present study confirms that rotavirus infection is still currently a prevalent gastroenteritis causative agent and required careful clinical attention. Pediatricians and health care providers are needed to be encouraged to take into account the children who at risk for developing rotavirus infection including age, residence and type of feeding.

Updates in the Prevalence of Rotavirus Gastroenteritis in Babylon City

2018 ◽  
pp. 1-12
Keyword(s):  
Health Care Providers ◽  
Rural Areas ◽  
Causative Organism ◽  
Care Providers ◽  
Sample Collection ◽  
Rotavirus Infection ◽  
Rotavirus Gastroenteritis ◽  
Age Range ◽  
Latex Test ◽  
Children Under 5

Background: Diarrhea is a main cause of morbidity and mortality in children under 5 years old. Globally it is responsible for approximately four billion cases and three million deaths annually. In developing countries, it causes two million deaths each year. The major causative organism is rotavirus which is responsible for one-third of hospitalizations with approximately 40% mortality. Objectives: To determine the prevalence and demographic characteristics of rotavirus infection in Babylon city, Iraq. Materials and Methods: Fecal samples were taken from children with age range of 6 months to 5 years complained of diarrhea during the period beginning in October 2016 till August 2017. The age, gender, residence, the type of feeding, place of the sample collection and duration of diarrhea were recorded. Specimens were analyzed by Latex test for detection of rotavirus. Results: A total of 349 children presented with diarrhea, the rotavirus antigen was detected in 169 fecal specimens from children with diarrhea (48%). More percentages of positive rotavirus specimens were seen in the 5year of age. No gender differences were observed, meanwhile samples obtained from rural areas and breastfed children showed less rotavirus positive infection. Conclusion: The present study confirms that rotavirus infection is still currently a prevalent gastroenteritis causative agent and required careful clinical attention. Pediatricians and health care providers are needed to be encouraged to take into account the children who at risk for developing rotavirus infection including age, residence and type of feeding.

Comparing the Genetic Detox Ability and Heavy Metal Burden in a Cohort of Samples of Egyptian Children and those with Autistic Spectrum Disorder

2019 ◽  
Author(s):  
Blaurock-Busch E
Keyword(s):  
Heavy Metal ◽  
Autism Spectrum ◽  
Control Group ◽  
Potentially Toxic Metals ◽  
Gstt1 Null Genotype ◽  
Egyptian Children ◽  
Glutathione S Transferases ◽  
Metal Burden ◽  
Detoxification Pathway

The heavy metal burden of patients with Autism spectrum disorders (ASD) has been widely discussed [1-5]. Present knowledge suggests that ASD patients, compared to ‘normal’s’ show a greater metal burden, which may be a cause of the ASD pathogenesis, possibly due to a limited detoxification potential. We thus aimed to evaluate if the metal burden of ASD children is due to comprised detoxification ability, and if missing of enzymes such as the glutathione-S-transferases provide an explanation, or if additional factors play a role. Genetically, we noticed a slight difference in the detoxification ability of the ASD group compared to the Control group. In the ASD group, carrier of the genotype GSTT1 null genotype (i.e. the homozygous loss) are 1.7 times more common as in the Control group and the GSTT1 allele is more frequent in the ASD patient collective. These findings are not statistically significant but indicate a trend. In addition, our data indicates that levels of potentially toxic metals in blood and hair of both groups demonstrate a similar immediate and long-term exposure. However, 36% of the ASD group showed signs of zinc deficiency compared to 11% of the Control group and this points towards inefficiency of the Phase I detoxification pathway. More research is needed to explore the role of other elements in the detoxification pathway.

Food Allergy in Preschool Egyptian Children with Recurrent Wheezy Chest

2020 ◽  
Author(s):  
Alameldin Abdallah ◽  
Naglaa S. Osman ◽  
Kotb A. Metwalley ◽  
Hanaa A Mohammad ◽  
Mostafa Embaby ◽  
...  
Keyword(s):  
Food Allergy ◽  
Egyptian Children

scholarly journals Toll-like receptor-4 gene variations in Egyptian children with familial Mediterranean fever

2021 ◽  
Vol 48 (1) ◽  
Author(s):  
Yomna Farag ◽  
Samia Salah ◽  
Hanan Tawfik ◽  
Mai Hamed ◽  
Huda Marzouk
Keyword(s):  
Familial Mediterranean Fever ◽  
Disease Severity ◽  
Gene Mutation ◽  
Rflp Analysis ◽  
Gene Variants ◽  
Gene Variant ◽  
Toll Like Receptor ◽  
Toll Like Receptor 4 ◽  
Egyptian Children ◽  
Mediterranean Fever

Abstract Background Familial Mediterranean fever (FMF) is an autosomal recessive disorder affecting people in the region of the Mediterranean Sea. It is usually associated with mutation in Mediterranean fever (MEFV) gene that encodes the pyrin protein, which affects the innate inflammatory response. Toll-like receptors (TLR) are a family of pattern recognition receptors that recognize pathogenic microbes and activate antimicrobial defense mechanisms. Toll-like receptor 4 (TLR-4) is concerned with recognition of gram-negative organisms. There is growing clinical evidence suggesting a role for expression of TLRs in the immune pathogenesis of FMF. Thus, the aim of the current study was to evaluate the presence of TLR-4 (p.Asp299Gly) and TLR-4 (p.Thr399Ile) gene variants in association with Egyptian children having FMF, furthermore, its effect on disease course and severity. Results Seventy Egyptian children diagnosed as having FMF, together with 50 age and gender-matched controls were enrolled in the study. The TLR-4 (p.Asp299Gly) and (Thr399Ile) gene variants were determined by PCR-RFLP analysis for all studied patients and controls. TLR-4 p.Asp299Gly gene variant was detected in 1 (1.4%) of the patients and p.Thr399Ile gene variant was detected in 2 (2%). None of the controls had any of the two tested gene variants. All found variations were heterozygous. We could not find a statistically significant association with disease severity in cases with or without TLR-4 gene variants (P = 0.568). Patients with M694V gene mutation showed a higher disease severity (P = 0.035). Conclusion TLR-4 (p.Asp299Gly) and (p.Thr399Ile) gene variants were not found to have a link with the occurrence, the clinical picture of FMF, its severity, and response to colchicine treatment in Egyptian children. M694V gene mutation seems to be associated with higher disease severity. Further larger studies are needed to verify these results.

Rotavirus Gastroenteritis in Eastern Uttar Pradesh, India

2021 ◽  
Author(s):  
Vineeta Gupta ◽  
Priyanka Aggarwal ◽  
Brajesh Kumar ◽  
Nayana P. Nair ◽  
Varunkumar Thiyagarajan ◽  
...  
Keyword(s):  
Uttar Pradesh ◽  
Rotavirus Gastroenteritis ◽  
Eastern Uttar Pradesh

Rotavirus Gastroenteritis Hospitalizations Among Under-Five Children in Bhubaneswar, Odisha, India

2021 ◽  
Author(s):  
Prasantajyoti Mohanty ◽  
Dilesh Kumar ◽  
Asit Mansingh ◽  
Varunkumar Thiyagarajan ◽  
Samarasimha Reddy N ◽  
...  
Keyword(s):  
Under Five ◽  
Under Five Children ◽  
Rotavirus Gastroenteritis

scholarly journals Benign Convulsions with Mild Rotavirus and Norovirus Gastroenteritis: Nationwide Data from the Health Insurance Review and Assessment Service in South Korea

Children ◽  
2021 ◽  
Vol 8 (4) ◽  
pp. 263
Author(s):  
Dong Hyun Kim ◽  
Dong Jun Ha ◽  
Yeong Seok Lee ◽  
Min Jun Chun ◽  
Young Se Kwon
Keyword(s):  
Health Insurance ◽  
South Korea ◽  
Large Scale ◽  
Rotavirus Vaccine ◽  
Annual Increase ◽  
Rotavirus Vaccination ◽  
Rotavirus Gastroenteritis ◽  
Norovirus Gastroenteritis ◽  
Increasing Trend

There have been no large-scale studies on the epidemiology of benign convulsions with mild gastroenteritis (CwG) since the introduction of the rotavirus vaccine in South Korea in 2007. This study aimed to analyze the trends in rotavirus gastroenteritis (RVGE) and rotavirus-associated CwG (RaCwG) after rotavirus vaccination. Further, we aimed to analyze changes in norovirus gastroenteritis (NVGE) and norovirus-associated CwG (NaCwG) using nationwide data from the Korean Health Insurance Review and Assessment Service. Between 2007 and 2019, this study analyzed children aged <6 years who were diagnosed with RVGE, NVGE, RaCwG and NaCwG. The changes in the prevalence of each disease and the ratio of CwG to enteritis were analyzed and the effects of age, sex and season were also analyzed. RVGE, RaCwG, NVGE and NaCwG were diagnosed in 273,898, 4246, 35,593 and 337 patients, respectively. The prevalence of RVGE was on a decreasing trend every year, but the prevalence of NaCwG and NVGE was on an increasing trend. There was a significant annual increase in the ratio of CwG to enteritis in both viruses. In order to control the prevalence of RaCwG, measures other than the rotavirus vaccine are required and measures to prevent norovirus are necessary.

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