Substantive Fluoride Release from a New Fluoride Varnish Containing CXP

Objective: The aim was to investigate the in vitro fluoride release from fluoride varnishes under acidic conditions. Study design: Poly(methyl methacrylate) blocks (Perspex, n=3 per group) were painted with 80±5 mg fluoride varnish (n=10) and placed into artificial saliva for 30min. Then, blocks were placed into either 1% citric acid (pH 2.27) or 0.3% citric acid (pH 3.75) solutions (n=3 per solution and varnish) for 30min with the solutions being replaced every 5min. Saliva and acid solutions were analyzed for fluoride content. Data were analyzed using three-way ANOVA (varnish, solution, time). Results: The three-way interaction was significant (p>0.0001). Fluoride release and release patterns varied considerably between varnishes. Fluoride release in saliva varied by a factor of more than 10 between varnishes. Some varnishes (CavityShield, Nupro, ProFluorid, Vanish) showed higher fluoride release in saliva than during the first 5min of acid exposure, whereas other varnishes (Acclean, Enamel-Pro, MI Varnish, Vella) showed the opposite behavior. There was little difference between acidic solutions. Conclusions: Fluoride release from fluoride varnishes varies considerably and also depends on the dissolution medium. Bearing in mind the limitations of laboratory research, the consumption of acidic drinks after fluoride varnish application should be avoided to optimize the benefit/risk ratio.

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Comparison of the Fluoride Release of Silver Diamine Fluoride, Fluoride Varnish, Acidulated Phosphate Fluoride Gel on Extracted Teeth over Various Time Intervals in Artificial Saliva

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i26a31471 ◽

2021 ◽

pp. 55-63

Author(s):

Taniya Thakur ◽

Pratik Kumar Lahiri ◽

Madhumanti Karmakar ◽

Bhumi Sarvaiya ◽

Piyali Datta ◽

...

Keyword(s):

Tap Water ◽

Artificial Saliva ◽

Fluoride Concentration ◽

Maximum Amount ◽

Fluoride Varnish ◽

Fluoride Ion ◽

Fluoride Release ◽

Silver Diamine Fluoride ◽

Group 4 ◽

Group 2

Silver Diamine Fluoride (SDF) has been documented to effectively arrest dental caries and reduce dental hypersensitivity. SDF promotes remineralization and harden the carious lesion. SDF increases fluoride concentration in saliva and increase the bioavailability of fluoride in saliva. After SDF application, fluoride ion promotes remineralization and silver ion is available for antimicrobial action. Aim: The study aims to determine and compare the amount of fluoride released from various fluoride releasing materials in artificial saliva after 24 hours, 7th day and 14th day of the study. Materials and Methods: 96 premolars free of any caries, fractures, or any other defects were sterilized in 10% formalin for 2 weeks. Then they were rinsed in tap water to remove any fixative from its surface and then stored in deionised distilled water for a period of 30 days prior to testing. Tooth samples were divided into four groups- Group 1: 38% SDF, Group 2: 1.23% APF gel, Group 3: Fluoride varnish and Group 4: Control. All the teeth specimens were blot dried and subjected to their respective material. Fluoride release was analysed using a Fluoride ion-selective electrode after 24 hours, 7days and 14 days of suspension in artificial saliva. Results: Mann-Whitney U Test for inter-group comparison was used for statistical evaluation. 24 Hours fluoride release: The maximum amount of fluoride was released from Fluoride Varnish followed by SDF then APF Gel and least by artificial saliva alone (control) (p<0.001). 7th Day fluoride release: The maximum amount of fluoride was released from SDF followed by Fluoride Varnish then APF Gel and least by artificial saliva alone (control) (p<0.001). 14th Day fluoride release: The maximum amount of fluoride was released from Fluoride Varnish followed by SDF then APF Gel and least by artificial saliva alone (control) (p<0.001).

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Fluoride Release from Two High-Viscosity Glass Ionomers after Exposure to Fluoride Slurry and Varnish

Materials ◽

10.3390/ma12223760 ◽

2019 ◽

Vol 12 (22) ◽

pp. 3760

Author(s):

Hani M. Nassar ◽

Jeffrey A. Platt

Keyword(s):

Analysis Of Variance ◽

Vickers Microhardness ◽

Fluoride Concentration ◽

Measurement Data ◽

High Viscosity ◽

Fluoride Content ◽

Fluoride Varnish ◽

Fluoride Release ◽

Glass Ionomer Cements ◽

Glass Ionomer

The effect of brushing with different fluoride slurries on the fluoride release (FR) of different high-viscosity glass ionomer cements (GICs) was investigated. Fifty-eight discs were fabricated from two high-viscosity GICs (GC Fuji IX (F9) and 3M ESPE Ketac-fil (KF)). Five specimens from each brand were used to measure Vickers microhardness and the remaining were randomly assigned to one of four groups (n = 6) based on two-factor combinations: (1) fluoride concentration in the abrasive slurry (275 or 1250 ppm fluoride as NaF) and (2) immersion in a 22,500 ppm fluoride-containing solution. Specimens were brushed for a total of 20,000 strokes over 4 days with daily FR measurement. Data were analyzed using analysis of variance and Bonferroni tests (α = 0.05). Baseline FR and microhardness values were different between the two tested material brands. Exposure to a 22,500 ppm solution was associated with higher FR but not the exposure to 1250 ppm slurries. Brushing and immersion of glass ionomer cements in a 22,500 ppm F solution led to higher FR that was more sustained for KF. Type of the glass ionomer, progressive brushing, and fluoride varnish affected FR but not the fluoride content in the abrasive slurry.

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Fluoride release from fluoride varnish under in vitro and in vivo conditions

Dental and Medical Problems ◽

10.17219/dmp/78887 ◽

2017 ◽

Vol 54 (4) ◽

pp. 327-331 ◽

Cited By ~ 1

Author(s):

Dagmara Piesiak-Pańczyszyn ◽

Urszula Kaczmarek

Keyword(s):

Fluoride Varnish ◽

Fluoride Release

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Evaluation of Short Term Fluoride Release from Fluoride Varnishes

Journal of Clinical Pediatric Dentistry ◽

10.17796/jcpd.36.3.q304488478w52334 ◽

2012 ◽

Vol 36 (3) ◽

pp. 275-278 ◽

Cited By ~ 12

Author(s):

P Ritwik ◽

JD Aubel ◽

X Xu ◽

Y Fan ◽

J Hagan

Keyword(s):

Maximum Rate ◽

Artificial Saliva ◽

Fluoride Varnish ◽

Fluoride Release ◽

Selective Electrode ◽

Short Term ◽

Statistical Tools ◽

Human Teeth ◽

Application Study ◽

Time Point

Objective: The aim of this study was to compare the rate of fluoride release from fluoride varnishes over a 48-hour period and ascertain the time at which a plateau occurred. This data provides clinically relevant time points to resume tooth brushing after fluoride varnish application. Study design: Four commercially available fluoride varnishes, Premier Enamel ProVarnish (EP), Colgate PreviDent (CP), Omni Vanish (OV) and Omni VanishXT (OVXT) were applied on 40 extracted permanent human teeth. Ten teeth served as controls. The teeth were immersed in artificial saliva. At 1,2,4,8,12,24 and 48 hours, the teeth were sequentially transferred to new vials. TISAB III and ion selective electrode was used to measure fluoride release. Statistical tools were used to compare the rates of fluoride release and plateau of fluoride release. Results: CP, EP and OV showed a plateau of fluoride release after 4 hours. OVXT did not show a significant change in fluoride release at any time point. EP had the highest fluoride release in the first 8 hours. Conclusions: CP, EP and OV released maximum rate of fluoride release in the first 4 hours whereas OVXT did not have a plateau. The studied varnishes released different concentrations of fluoride despite the fact that they all contained 5% sodium fluoride.

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Orthodontic cements: immediate protection and fluoride release

Dental Press Journal of Orthodontics ◽

10.1590/s2176-94512012000400010 ◽

2012 ◽

Vol 17 (4) ◽

pp. e1-e5

Author(s):

Rogério Lacerda dos Santos ◽

Matheus Melo Pithon ◽

Júlia Barbosa Pereira Leonardo ◽

Edna Lúcia Couto Oberosler ◽

Delmo Santiago Vaitsman ◽

...

Keyword(s):

Sodium Fluoride ◽

Fluoride Varnish ◽

Fluoride Release ◽

Glass Ionomer Cements ◽

Glass Ionomer ◽

Selective Electrode ◽

Group V ◽

Cem Cement ◽

Significant Difference ◽

Uptake And Release

OBJECTIVES: The objective of the authors was to evaluate fluoride release of 3 glass ionomer cements with immediate protection of fluoride varnish (Cavitine, SS White), divided into 3 groups: Group M (Meron, VOCO), Group V (Vidrion C, SS White) and Group KC (Ketac-Cem, 3M ESPE). METHODS: Fluoride release was measured during 60 days by means of an ion-selective electrode connected to an ion analyzer. After 4 weeks, the test specimens were exposed to a solution of 0.221% sodium fluoride (1000 ppm of fluoride). RESULTS: Results showed that the cements reached a maximum peak of fluoride release in a period of 24 h. There was a statistically significant difference between the amount of fluoride released after the applications of fluoride among the groups from the 31st to 60th day (p> 0.05). CONCLUSION: The Vidrion C and Meron cements showed better performance to uptake and release fluoride when compared with Ketac-Cem cement.

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