Investigation of the Effect of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)on Vascular Endothelial Function in Coronary Slow Flow (CSF) Patients

2016 ◽  
Vol s1 ◽  
Author(s):  
Yuan Li ◽  
Huiping Zhang ◽  
Yafeng Hao
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Endothelial Function ◽  
Slow Flow ◽  
Vascular Endothelial ◽  
Vascular Endothelial Function ◽  
Obstructive Sleep ◽  
Coronary Slow Flow ◽  
Hypopnea Syndrome

Endothelial Function of Patients with Morbid Obesity Submitted to Roux-en-Y Gastric Bypass With and Without Obstructive Sleep Apnea-Hypopnea Syndrome

2018 ◽  
Vol 28 (11) ◽  
pp. 3595-3603 ◽  
Author(s):  
Ana Cristina de Assunção Machado ◽  
Antonio Marcos Vargas da Silva ◽  
Luis Ulisses Signori ◽  
Glauco da Costa Alvarez ◽  
Claudio Corá Mottin
Keyword(s):  
Morbid Obesity ◽  
Obstructive Sleep Apnea ◽  
Gastric Bypass ◽  
Sleep Apnea ◽  
Endothelial Function ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

Levels of vascular endothelial growth factor are elevated in patients with obstructive sleep apnea–hypopnea syndrome

Blood ◽  
2001 ◽  
Vol 98 (4) ◽  
pp. 1255-1257 ◽  
Author(s):  
Shigehiko Imagawa ◽  
Yuji Yamaguchi ◽  
Masato Higuchi ◽  
Tomohiro Neichi ◽  
Yuichi Hasegawa ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Growth Factor ◽  
Vascular Endothelial ◽  
Obstructive Sleep ◽  
A Minor ◽  
Endothelial Growth Factor ◽  
Hypopnea Syndrome ◽  
Serum Erythropoietin

To better understand how humans adapt to hypoxia, the levels of hemoglobin (Hb), serum erythropoietin (Epo), and vascular endothelial growth factor (VEGF) were measured in 106 patients with severe obstructive sleep apnea-hypopnea syndrome. The results indicated that temporal hypoxic stimulation increases Hb. Furthermore, a minor increase in Epo and a substantial increase in VEGF were found. The induction in patients with severe sleep apnea was greater than that reported in other types of hypoxia.

scholarly journals Roles and Mechanisms of Obstructive Sleep Apnea-Hypopnea Syndrome and Chronic Intermittent Hypoxia in Atherosclerosis: Evidence and Prospective

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Linqin Ma ◽  
Jingchun Zhang ◽  
Yue Liu
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Intermittent Hypoxia ◽  
Underlying Mechanism ◽  
Endothelial Injury ◽  
Current Evidence ◽  
Chronic Intermittent Hypoxia ◽  
Vascular Endothelial ◽  
Obstructive Sleep ◽  
Hypopnea Syndrome

The morbidity and mortality of obstructive sleep apnea-hypopnea syndrome (OSAHS) are regarded as consequences of its adverse effects on the cardiovascular system. Chronic intermittent hypoxia (CIH) induced by OSAHS can result in vascular endothelial injury, thus promoting development of atherosclerosis (AS). Studies have shown that CIH is an independent risk factor for the occurrence and development of AS, but the underlying mechanism remains unclear. Here, we review clinical and fundamental studies reported during the last 10 years on the occurrence and development of AS mediated by CIH, focusing on inflammation, oxidative stress, insulin resistance, cell apoptosis, vascular endothelial injury, platelet activation, and neuroendocrine disorders. This review will offer current evidence and perspective to researchers for the development of effective intervention strategies for OSAHS-related cardiocerebrovascular diseases.

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