scholarly journals Sub-acute Toxicity of Aqueous Extracts of Tephrosia vogelii, Vernonia amygdalina and Senna occidentalis in Rats

2014 ◽  
Vol 2 (5) ◽  
Author(s):  
Nabukenya I
Keyword(s):  
Acute Toxicity ◽  
Aqueous Extracts ◽  
Vernonia Amygdalina ◽  
Tephrosia Vogelii

Acute toxicity and safety profile evolution of aqueous extracts of Sanren decoction using in vivo models

2021 ◽  
pp. 114940
Author(s):  
Qing Wang ◽  
Liutao Zhao ◽  
Hui Zhang ◽  
Shuo Zhang ◽  
Pu Yang ◽  
...  
Keyword(s):  
Acute Toxicity ◽  
Safety Profile ◽  
Aqueous Extracts ◽  
In Vivo Models

scholarly journals Antibacterial Potentials of Vernonia amygdalina against Antibiotic-Resistant Salmonella Specie Isolated from Nworie River, Imo State, Nigeria

2016 ◽  
Vol 56 ◽  
pp. 82-89 ◽  
Author(s):  
Chinwe I. Chikwendu ◽  
Emmanuel Egbadon ◽  
Blessing Okuma
Keyword(s):  
Aqueous Ethanol ◽  
Aqueous Extracts ◽  
Bacterial Isolates ◽  
Vernonia Amygdalina ◽  
Antibiotic Resistant ◽  
Imo State ◽  
Acetone Extracts ◽  
Antibacterial Potential

Salmonella specie were isolated from Nworie River and then tested against several antibiotics to include; Gentamycin, Streptomycin, Amoxycillin, Kanamycin, Oxacillin, Ofloxacin, Imipenem, Ciprofloxacin, Aztreonam and Ceftazidime. Salmonella isolates obtained from the river were resistant to at least three different antibiotics. All isolates were resistant to Amoxycillin, Oxacillin and Iminipem showing a 100% resistant rate, while showing sensitivity to Ciprofloxacin, Aztreonam, Gentamycin, Ceftazidime, Kanamycin, Streptomycin, and Ofloxacin at sensitivity rates of 71.4%, 7.1%, 77.1%, 11.4%, 44.3%, 48.6% and 78.6% respectively. The antibiotic-resistant Salmonella species were further tested against the aqueous, ethanol and acetone extracts of Vernonia amygdalina leaf, stem and roots to assess their antibacterial potential at a concentration of 100mg/ml. Aqueous extracts of the leaf, stem and roots showed no activity against antibiotic resistant Salmonella isolate, while the ethanol and acetone extracts showed activity rates of 20% and 17% for roots, 14.3% and 12.9% for stem, and, 15.7% and 11.4% for leaf. The results from this study further confirms the antibacterial potentials of Vernonia amygdalina against antibiotic-resistant bacterial isolates.

scholarly journals In Vitro Antibacterial Activity of an Aqueous Extracts of the Tephrosia Vogelii Hook.f Combined To Imipenem on E. coli Strains

2020 ◽  
Vol 09 (01) ◽  
pp. 36-45
Author(s):  
 Jean Fabrice Yala ◽  
Rolande Mabika Mabika ◽  
Franck Mounioko ◽  
Ornella Zong Minko ◽  
Alexis Nicaise Lepengue ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Aqueous Extracts ◽  
E Coli ◽  
Tephrosia Vogelii ◽  
In Vitro Antibacterial Activity

scholarly journals Acute Toxicity and Dose Fixation Studies on Chloroxylon swietenia Dc Bark Extracts on Streptozotocin Induced Diabetic Rats

2015 ◽  
Vol 48 ◽  
pp. 8-13 ◽  
Author(s):  
B. Jayaprasad ◽  
P.S. Sharavanan ◽  
R. Sivaraj
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Disease ◽  
Body Weight ◽  
Acute Toxicity ◽  
Wistar Rats ◽  
Diabetic Rats ◽  
Aqueous Extracts ◽  
Single Intraperitoneal Injection ◽  
Toxic Reactions ◽  
Chloroxylon Swietenia

Diabetes mellitus (DM) is a chronic metabolic disease with the highest rates of prevalence and mortality worldwide. Chloroxylonswietenia has been used extensively in folkloric medicine. The present study aims to determine the acute toxicity of Chloroxylonswietenia bark methanol (CSBMEt) and aqueous extracts (CSBAEt) (100, 150, 250, 500 and 1000 mg/kg body weight) and dose fixation of CSBMEt and CSBAEt in streptozotocin induced diabetic rats. Diabetes was induced in male albino wistar rats by single intraperitoneal injection of streptozotocin (50mg/kg b.w). The diabetic rats were administered with Chloroxylonswietenia bark extracts (CSBMEt and CSBAEt) (75,125 and 250mg/kg b.w) orally by intragastric intubation for 15 days. Acute toxicity studies revealed the non-toxic nature of the CSBMEt and CSBAEt. No lethality or toxic reactions found at any doses until the end of study, whereas 75 and 125 mg/kg b.w. doses of CSBMEt and CSBAEt produce no significant changes in the diabetic rats and 250mg/kg b.w. of CSBMEt and CSBAEt have significant change in the blood glucose. The results conclude that, there was no toxicity observed up to 1000mg/kg b.w. of both the extracts and 250mg/kg b.w. of CSBMEt and CSBAEt can be used as effective dose to treat diabetes.

scholarly journals Efficacy of Aqueous Extracts from Syzygium aromaticum, Tephrosia vogelii, and Croton dichogamus against Myzus persicae on Brassica oleracea in Northern Tanzania

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Nelson Mpumi ◽  
Kelvin M. Mtei ◽  
Revocatus L. Machunda ◽  
Patrick A. Ndakidemi
Keyword(s):  
Brassica Oleracea ◽  
Myzus Persicae ◽  
Smallholder Farmers ◽  
Positive Control ◽  
Syzygium Aromaticum ◽  
Aqueous Extracts ◽  
Chemical Insecticide ◽  
Northern Tanzania ◽  
Tephrosia Vogelii ◽  
Negative Controls

The effectiveness of 1, 5, and 10% w/v of aqueous extracts of Croton dichogamus, Tephrosia vogelii, and Syzygium aromaticum and their mixture (2.5 and 5%) was evaluated against Myzus persicae on Brassica oleracea under field conditions. The synthetic chemical insecticide, chlorpyrifos, was used as positive control, and water and water plus soap were used as negative controls. Aqueous extracts significantly ( P ≤ 0.05 ) lowered M. persicae population compared with negative controls. The 5% of the aqueous extract from mixed plants and 10% of each plant used in this study significantly ( P ≤ 0.01 ) reduced aphid, M. persicae population comparable to chlorpyrifos in 2019 and 2020. However, the 1 and 5% concentrations of aqueous extracts of C. dichogamus, T. vogelii, and S. aromaticum and 2.5% of aqueous extracts from the mixed plants significantly lowered the population of M. persicae compared with negative controls in 2019 and 2020 wet seasons. The weekly observations revealed that, at weeks 1, 2, 3, 4, and 5 after application of treatments, the population of M. persicae differed significantly ( P ≤ 0.05 ). Also, the aqueous extracts from the mixed plants at 5% concentrations significantly ( P ≤ 0.01 ) reduced M. persicae population as compared with other treatments. It was as effective as synthetic chemical pesticide (chlorpyrifos). Also, 1 and 5% of C. dichogamus, T. vogelii, and S. aromaticum and the 2.5% of aqueous extracts from the mixed plants significantly reduced the population of M. persicae for all 6 weeks of study compared with negative controls. Therefore, these pesticidal plants can be recommended to smallholder farmers for the control of M. persicae in B. oleracea crops.

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