Phytopharmacology of Chloroxylon swietenia: a review

The nature has provided a complete store house of remedies to use for all ailments for mankind. The knowledge on drugs has accumulated over thousands of years as a result of mans inquisitive nature. Phytomedicines or natural prescriptions, have assumed a basic part in World wellbeing for a large number of years. As per the World Health Organization (WHO), "natural medications incorporate herbs, home grown materials, home grown arrangements and completed home grown items, that contain as dynamic fixings parts of plants, or other plant materials, or blends. Chloroxylon swietenia DC. (Family: Rutaceae) is an important traditional medicinal plant used in the treatment of various ailments like fungal infection of skin, rheumatism, common cold, cough, ophthalmic infection and cataract, wounds and as an astringent. It is a tropical aromatic tree of dry deciduous forests popularly known as East Indian Satin Wood. The findings of this study will facilitate pharmacognostic standardization of the plant material and aid in the preparation of an herbal monograph for the species. Further studies on this plant must be carried out to explore some other important, necessary and unknown benefits. As the plant has multifunctional properties, this review is worthwhile and therefore it presents comprehensive analysed information on the phytochemical and pharmacological aspects of the botanical. Keywords: Chloroxylon swietenia, phytomedicines, pharmacological aspects, anti-feedant, anti-bacterial activity, IUCN, vulnerable species.

Antihyperlipidemic activity of Chloroxylon swietenia in triton WR1339 induced hyperlipidemia

Background: Medicinal herbs are beneficial and effective either in the management and prevention of several metabolic disorders, associated with hyperlipidemia, hypertension and insulin resistance which increases the cardio-metabolic risk and demands for the life time therapy. Current allopathic medicines are expensive and reported with several adverse effects and hence, finding of a suitable herbal medicine for hyperlipidemic disorders is very important.Methods: Thirty albino rats weighing 200-230g were randomly divided into 5 groups were rendered hyperlipidemia with a single dose of triton WR 1339. Normal control, positive control, standard, aqueous and ethanolic extract groups were treated with tween-80, tween-80, atorvastatin, aqueous and ethanolic extracts of Chloroxylon swietenia respectively for seven days. At the end of the study, blood was collected for estimation of the lipid profile.Results: Both the aqueous and ethanolic extract groups significantly reduced the TG and VLDL levels.Conclusions: The extracts exhibited remarkable activity on one or either parameter of the lipid profile. It could be due to the presence of alkaloids, steroids, flavonoids, coumarins and phenols in the extracts.