scholarly journals Prevalence of Severe Anemia (Hb ≤ 5 g/dl) in Non-Dialyzed Chronic Renal Failure Patients in the Nephrology and Hemodialysis Department of Point G University Hospital

2021 ◽  
Vol 11 (02) ◽  
pp. 252-264
Author(s):  
Seydou Sy ◽  
Magara Samaké ◽  
Aboubacar Sidiki Fofana ◽  
Awa Diallo ◽  
Moctar Coulibaly ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
University Hospital ◽  
Severe Anemia ◽  
Point G

scholarly journals Digestive Pathologies during Chronic Renal Failure in the Nephrology and Haemodialysis Department at the University Hospital Center of Point G in Mali

2020 ◽  
Vol 10 (01) ◽  
pp. 41-48
Author(s):  
Magara Samaké ◽  
Seydou Sy ◽  
Hamadoun Yattara ◽  
Moctar Coulibaly ◽  
Mamadou Badou Sanogo ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
University Hospital ◽  
Point G ◽  
The University ◽  
Hospital Center

scholarly journals Bacteriological Profile of Pneumopathies in Chronic Renal Failure at the University Hospital Center of Point-G in Mali

2020 ◽  
Vol 10 (01) ◽  
pp. 18-28
Author(s):  
Seydou Sy ◽  
Magara Samaké ◽  
Hamadoun Yattara ◽  
Moctar Coulibaly ◽  
Ba Oumou Diallo ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
University Hospital ◽  
Bacteriological Profile ◽  
Point G ◽  
The University ◽  
Hospital Center

scholarly journals Prevalence and Etiologies of Obstructive Renal Failure in the Nephrology Department of the University Hospital Center of Point G, Bamako, Mali

2020 ◽  
Vol 10 (03) ◽  
pp. 187-198
Author(s):  
Seydou Sy ◽  
Magara Samaké ◽  
Moctar Coulibaly ◽  
Moussa Salifou Diallo ◽  
Atabième Kodio ◽  
...  
Keyword(s):  
Renal Failure ◽  
University Hospital ◽  
Point G ◽  
The University ◽  
Obstructive Renal Failure ◽  
Hospital Center

Homocitrulline: a new marker for differentiating acute from chronic renal failure

2016 ◽  
Vol 54 (1) ◽  
Author(s):  
Aurore Desmons ◽  
Stéphane Jaisson ◽  
Christine Pietrement ◽  
Philippe Rieu ◽  
Alain Wynckel ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Characteristic Curve ◽  
University Hospital ◽  
Isocyanic Acid ◽  
Post Translational Modification ◽  
Amino Groups ◽  
Concentration Peak ◽  
The University ◽  
Kinetics Of

AbstractCarbamylation is a non-enzymatic post-translational modification of proteins characterized by the addition of isocyanic acid to amino groups. As isocyanic acid mainly originates from the spontaneous dissociation of urea, carbamylation rate is increased during renal failure. The aim of the study was to evaluate serum homocitrulline (HCit), which results from the carbamylation of ε-amino groups of lysine (Lys) residues, in acute renal failure (ARF) and to determine if it could be useful for differentiating acute from chronic renal failure (CRF).In total, 213 patients with renal failure referred to the nephrology department of the university hospital of Reims were included. Patients were classified into three groups: patients with ARF (ARF group, n=39), patients with CRF complicated with ARF (A/CRF group, n=29) and patients with CRF (CRF group, n=145). Serum HCit concentrations were measured by LC-MS/MS. Concentration kinetics of HCit and urea were studied in patients suffering from ARF. The HCit thresholds distinguishing ARF and CRF were investigated.HCit concentrations increased in ARF patients reaching a peak delayed compared to urea concentration peak. HCit concentrations were positively correlated with urea concentrations (r=0.51) and with the time elapsed since the estimated onset of ARF (r=0.57). Serum HCit concentrations were higher (p<0.05) in CRF group compared to ARF group. The receiver operating characteristic curve analysis showed that HCit concentrations <289 μmol/mol Lys were predictive of ARF (Sensitivity: 83%, Specificity: 72%, AUC: 0.856).Our results demonstrate that HCit is a promising biomarker for distinguishing between ARF and CRF patients.

scholarly journals Purtscher-like retinopathy in a 56-year-old Thai female with anti-glomerular basement membrane glomerulonephritis

2016 ◽  
Vol 14 (3) ◽  
pp. 129-136
Author(s):  
Supalert Prakhunhungsit ◽  
Rossukon Khotcharrat
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Basement Membrane ◽  
Plasma Exchange ◽  
Creatinine Level ◽  
Glomerular Basement Membrane ◽  
Anterior Segment ◽  
University Hospital ◽  
Total Plasma ◽  
Total Plasma Exchange

A 56-year-old Thai female was referred to Naresuan university hospital with anemia and pitting edema both legs. She had underlying diseases of hypertension, hypercholesterolemia and chronic renal failure with anemia. Before her referral, she was treated by an internist at a provincial hospital. With deterioration of creatinine level and anemic symptom, she was advised to see a nephrologist for the diagnosis of causative pathology and treatment. The reevaluation of chronic renal failure was done. The results of laboratory investigation were creatinine level of 2.42 mg/dl, blood urea nitrogen (BUN) 44 mg/dl and the urinalysis found microscopic hematuria. Further evaluations for hematuria ; vaginoscopy, cystoscopy and ultrasonography of genitourinary system, were performed consequently but all investigations were unremarkable. Then, renal biopsy was done with the result of anti-glomerular basement membrane glomerulonephritis. The hemodialysis and total plasma exchange were done several times to reduce the antibody of anti glomerular basement membrane level.During her admission, she complained of sudden blurred vision both eyes after the ninth total plasma exchange. She has no previous ocular problems nor physical trauma. The ocular examination showed visual acuity of counting fingers both eyes. Anterior segment was unremarkable for her age. The posterior segments showed retinal thickening around the posterior poles with clear intervening zones both eyes with some intraretinal hemorrhage which was compatible with Purtscher-like retinopathy by clinical. The pathogenesis of Purtscher-like retinopathy was investigated with negative results. The counseling was done and the treatment of observation was chosen by the patient and her family. Then she was discharged and followed up at out patient unit of ophthalmology department, Naresuan university hospital.   Conclusion: The Purtscher-like retinopathy is a rare ocular disease with  variable treatment strategies and outcomes. In complicated case without obvious causes, the pathogenesis of the disease should be investigated which directed to the proper treatment and better visual outcome.

scholarly journals Role of Balloon Assisted Maturation Technique in the Rate of AVF Maturation in Chronic Renal Failure Patients

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M S Khatab ◽  
S M Essam ◽  
H Aboelfotoh
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
University Hospital ◽  
Secondary Patency ◽  
City Hospital ◽  
Arteriovenous Fistulas ◽  
Secondary Patency Rate ◽  
Patient Morbidity

Abstract Background the current recommendations from the National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKFDOQI) favors the use of arteriovenous fistulas (AVF) over grafts and central catheters, in an effort to decrease cost, increase long term patency, reduce interventions and decrease patient morbidity. Purpose this study was designed to determine the rate of AVF maturation using the (BAM) technique; the primary and secondary patency rate and to evaluate the feasibility and safety of the (BAM) technique for the immature or failed AVF. Patients and Methods 30 chronic renal failure patients were selected for the purpose of this study from patients presented to vascular surgery clinic, Ain Shams University Hospital and Nasr City Hospital. Results this study included 30 arteriovenous fistula, belonging to 30 chronic renal failure patient. Their mean age was 57.6 years (±14.6). The demographic characteristics and risk factor distribution are shown below. Conclusion endovascular techniques have an important role to play in helping the dialysis community meet the goals of the Fistula First Initiative. To meet these goals, the previously mentioned techniques need to be used in varying degrees to salvage &gt; 95% of the nearly 60% of AVFs that fail to mature. When prolonged catheter time is taken into account, it is imperative to have a systematic method for salvaging these failing accesses before catheter-related complications are encountered.

scholarly journals Assesment of health-related quality of life with patient chronic kidney disease at hasanuddin university hospital

2021 ◽  
Vol 2 (1) ◽  
pp. 145-149
Author(s):  
Fajriansyah ◽  
Andi Paluseri ◽  
Riswandy Wasir ◽  
Mujriah
Keyword(s):  
Quality Of Life ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Kidney Disease ◽  
Short Form ◽  
University Teaching ◽  
University Hospital ◽  
Average Score ◽  
Scale Item

Measuring the quality of life can be used as a reference for the success of an action or therapy as well as initial data in formulating the right action for the patient. This study aims to provide an overview of the quality of life of patients with chronic renal failure who seek treatment at the Hasanuddin University teaching hospital. The research design used was an observational cross-sectional design with data collection carried out by filling out a questionnaire prospectively. The subjects of the study were chronic renal failure patients undergoing hemodialysis who met the inclusion and exclusion criteria and were selected using a non-random sampling technique by means of total sampling. The patient's quality of life was measured using the Kidney Disease Quality of Life Short Form (KDQOL-SFtm) Indonesian version 1.3 questionnaire. A total of 30 patients were willing to participate in this study. The results of the study on 30 patients with chronic renal failure, there were 7 out of 19 scale/item having a not good, namely burden of kidney disease, work status, sleep, physical functioning, role-physical, pain, and general health. The average value of 19 scale/item shows an average score of> 59.37, which is 63.86 which belongs to the good quality of life category.

Parenteral Iron Therapy in Cancer-Associated Anemia

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 351-356 ◽  
Author(s):  
David H. Henry
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Intravenous Iron ◽  
Severe Anemia ◽  
Anemia Of Chronic Disease ◽  
Common Causes ◽  
Parenteral Iron ◽  
Parenteral Iron Therapy ◽  
Esa Therapy ◽  
Rule Out

AbstractAnemia is common in cancer patients. Its cause is multifactorial, so a brief workup is always necessary to rule out simple, reversible causes. Anemia of chronic disease/inflammation and chemotherapy-induced anemia are the most common causes. Symptomatic or clinically severe anemia may require treatment with blood transfusion or an erythropoiesis-stimulating agent (ESA). If ESA therapy is chosen, developing evidence now suggests that, similar to chronic renal failure patients on hemodialysis, the addition of intravenous iron can improve the response to ESA because of iron-restricted erythropoiesis, even in the iron-replete patient.

scholarly journals The anemia of chronic renal failure and chronic diseases: in vitro studies of erythropoiesis

Blood ◽  
1976 ◽  
Vol 47 (4) ◽  
pp. 561-569
Author(s):  
SF Wallner ◽  
JE Kurnick ◽  
HP Ward ◽  
R Vautrin ◽  
AC Alfrey
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Human Serum ◽  
Chronic Diseases ◽  
Normal Serum ◽  
Severe Anemia ◽  
Serum Factor ◽  
Heme Synthesis ◽  
Guanidinosuccinic Acid

The presence of a serum factor in chronic renal failure (CRF) which inhibits erythropoietin-stimulated erythropoiesis was studied, using a technique in which dog marrow cells were stimulated to produce heme in the presence of human serum. In the total series comparing 27 normal sera with 52 CRF sera, less heme was synthesized when the system contained CRF sera (total series, p = 0.0001). There was no evidence of inhibition of heme synthesis by serum from 12 patients with the anemia of chronic diseases (CD). Mixing experiments with normal and CRF sera suggested that this defect in CRF serum was not due to lack of a factor necessary for heme synthesis. Addition of urea, creatinine, and guanidinosuccinic acid to normal serum did not impair its ability to support erythropoiesis in this system. These data demonstrated that serum from patients with CRF contains a material inhibiting erythropoiesis in vitro, We propose that the material is responsible, in part, for the clinically severe anemia seen in these patients.

scholarly journals DYSLIPIDIMIA

2015 ◽  
Vol 22 (07) ◽  
pp. 865-870
Author(s):  
Ashok Kumar Lohano ◽  
Irfan Ahmed Bhatti ◽  
Azhar Iqbal ◽  
Salman Shah Jilani
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Lipid Profile ◽  
Venous Blood ◽  
Age Groups ◽  
Operational Definition ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Lipid Lowering ◽  
Cross Sectional

Objective: To determine the various lipid profile pattern of dyslipidimia in patientsof chronic renal failure. Study design: Cross-sectional study. Place and duration of study:This study was conducted at Nephrology department of Isra University hospital Hyderabadand Medicine Department Civil hospital Nawabshah, from October 2013 to September 2014.Methodology: This study consisted of 237 patients of chronic renal failure asses on detailedhistory regarding chronic renal failure, patients were subject to relevant investigations i.e.fasting lipid profile and venous blood was drawn after 14 hours fasting state in the early morningand sent to laboratory for analysis of fasting lipid profile. Inclusion Criteria were all patients ofchronic renal failure with 1years history, age > 35 to 60 years and either any sex. Diagnosed onthe basis of serum creatinine as define in operational definition. Exclusion Criteria were patientson lipid lowering agents, acute complication of diabetes mellitus such as diabetic keto-acidosis,patients suffering from hypothyroidism, type 1 DM and HTN, lactic-acidosis, hypoglycemia.Results were prepared with help of tables and graphs. Data was analyzed through SPSS software.Results: Out of 237 patients, 113(47.68%) patients were 51 to 60 years of age, 94(39.66%) were41 to 50 years of age and 30(12.66%) were 35 to 40 years as presented in Chart No 1. Theaverage age of the patients was 50.11±6.94 years. There were 54.43% (129/237) male and45.57% (108/237) female. Various lipid profile pattern of dyslipidimia in patients of chronic renalfailure are presented in table-I. Results of fasting lipid profile are Triglycerides high in 86(36.3%),HDL low in 76(32.1%) cases, LDL in high 83(35%) cases, Cholesterol high in 105(44.3%) casesand VLDL-cholesterol high in 68(28.7%). Stratification analysis showed that lipid profile patternof dyslipidemia was insignificant between male and female as presented in table 2. While withrespect to age groups, rate of Cholesterol, triglycerides, LDL-cholesterol was high in above40 years of age groups as compare to 30 to 40 years of age groups. Rate of low HDL wasalso high in above 40 years of age groups as compare to 30 to 40 years as presented in table3. Conclusions: In conclusion, our study demonstrated that dyslipidemia often our patientschronic renal failure. This underscores the need for the first test patients with lipid abnormalitiesearly treatment can prevent cardiovascular events delay chronic kidney disease.

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