scholarly journals Inhibitory effect of alternatively spliced RAGEv1 on the expression of NF-kB and TNF-α in hepatocellular carcinoma cells

2012 ◽  
Vol 11 (2) ◽  
pp. 1712-1720 ◽  
Author(s):  
T. Lertwittayapon ◽  
T. Tencomnao ◽  
R. Santiyanont
Keyword(s):  
Hepatocellular Carcinoma ◽  
Inhibitory Effect ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Tnf Α ◽  
Alternatively Spliced

Inhibitory effect of extract of fungi of Huaier on hepatocellular carcinoma cells

2009 ◽  
Vol 29 (2) ◽  
pp. 198-201 ◽  
Author(s):  
Jianzhuang Ren ◽  
Chuansheng Zheng ◽  
Gansheng Feng ◽  
Huimin Liang ◽  
Xiangwen Xia ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Inhibitory Effect ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells

Cross-talk between TNF-α and IFN-γ signaling in induction of B7-H1 expression in hepatocellular carcinoma cells

2017 ◽  
Vol 67 (2) ◽  
pp. 271-283 ◽  
Author(s):  
Na Li ◽  
Jianing Wang ◽  
Na Zhang ◽  
Mengwei Zhuang ◽  
Zhaoyun Zong ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cross Talk ◽  
Carcinoma Cells ◽  
Hepatocellular Carcinoma Cells ◽  
Tnf Α ◽  
Ifn Γ

Anticancer Activities and Mechanisms of Blumea balsamifera Extract in Hepatocellular Carcinoma Cells

2008 ◽  
Vol 36 (02) ◽  
pp. 411-424 ◽  
Author(s):  
Toshio Norikura ◽  
Akiko Kojima-Yuasa ◽  
Miki Shimizu ◽  
Xuedan Huang ◽  
Shenghui Xu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Therapeutic Potential ◽  
Cell Model ◽  
Rat Hepatocytes ◽  
Inhibitory Effect ◽  
Carcinoma Cells ◽  
Anticancer Activities ◽  
Hepatocellular Carcinoma Cells ◽  
Proliferative Effect ◽  
Growth Inhibitory

Blumea balsamifera (also known as sambong), a medicinal plant, is known to improve physiological disorders such as rheumatism and hypertension. However, its anticancer activity has not been well elucidated. In this study, we found that Blumea balsamifera MeOH extract (BME) induced growth inhibitory activity in rat and human hepatocellular carcinoma cells (McA-RH7777, HepG2, respectively) without cytotoxicity as in with rat hepatocytes used as a normal cell model. BME induced cell cycle arrest at G1 phase via decreases in expression of cyclin-E and phosphorylation of retinoblastoma (Rb) protein in both dose- and time-dependent manners. Furthermore, BME reduced the level of a proliferation related ligand (APRIL) which stimulates tumor cell growth. The anti-proliferative effect of BME was improved slightly but significantly by the treatment with recombinant human APRIL. These findings suggest that BME may have a possible therapeutic potential in hepatoma cancer patients and the depletion of cellular APRIL may be one of the important mechanisms on the growth inhibitory effect of BME.

scholarly journals Therapeutic Effects of Phyllanthus Species: Induction of TNF-α-mediated Apoptosis in HepG2 Hepatocellular Carcinoma Cells

2006 ◽  
Vol 1 (4) ◽  
pp. 65-71 ◽  
Author(s):  
Sripathi M. Sureban ◽  
Dharmalingam Subramania ◽  
Paramasivam Rajendran ◽  
Rama P. Ramanujam ◽  
Brian K. Dieckgraef ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Carcinoma Cells ◽  
Therapeutic Effects ◽  
Hepatocellular Carcinoma Cells ◽  
Tnf Α
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