Determination of some haematological parameters in malaria infected subjects in Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto, Nigeria

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.

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Determination of lead levels in maternal and umbilical cord blood at birth at the Lagos University Teaching Hospital, Lagos

PLoS ONE ◽

10.1371/journal.pone.0211535 ◽

2019 ◽

Vol 14 (2) ◽

pp. e0211535 ◽

Cited By ~ 4

Author(s):

Jejelola I. Ladele ◽

Iretiola Bamikeolu Fajolu ◽

Veronica Chinyere Ezeaka

Keyword(s):

Cord Blood ◽

Umbilical Cord ◽

Teaching Hospital ◽

Umbilical Cord Blood ◽

University Teaching ◽

Lead Levels

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Glucose-6- Phosphate Dehydrogenase Activity in Newborn in Jos: A Necessary Evaluation for Icteric Neonates

Journal of BioMedical Research and Clinical Practice ◽

10.46912/2i4.2019127 ◽

2019 ◽

Vol 2 (4) ◽

pp. 191-196

Author(s):

ED Jatau ◽

OB Toma ◽

OJ Egesie ◽

DO Damulak ◽

Z Ayuba ◽

...

Keyword(s):

Teaching Hospital ◽

Clinical Information ◽

Redox Status ◽

G6pd Activity ◽

University Teaching ◽

Activity Levels ◽

Evaluation Tool ◽

Plateau State ◽

Glucose 6 Phosphate Dehydrogenase

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.

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Glucose-6- Phosphate Dehydrogenase Activity in Newborn in Jos: A Necessary Evaluation for Icteric Neonates

Journal of BioMedical Research and Clinical Practice ◽

10.46912/jbrcp2i4.2019127 ◽

2019 ◽

Vol 2 (4) ◽

pp. 191-196

Author(s):

ED Jatau ◽

OB Toma ◽

OJ Egesie ◽

DO Damulak ◽

Z Ayuba ◽

...

Keyword(s):

Teaching Hospital ◽

Clinical Information ◽

Redox Status ◽

G6pd Activity ◽

University Teaching ◽

Activity Levels ◽

Evaluation Tool ◽

Plateau State ◽

Glucose 6 Phosphate Dehydrogenase

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.

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Glucose-6- Phosphate Dehydrogenase Activity in Newborn in Jos: A Necessary Evaluation for Icteric Neonates

Journal of BioMedical Research and Clinical Practice ◽

10.46912/jbrcp.v2.i4.2019.127 ◽

2019 ◽

Vol 2 (4) ◽

pp. 191-196

Author(s):

ED Jatau ◽

OB Toma ◽

OJ Egesie ◽

DO Damulak ◽

Z Ayuba ◽

...

Keyword(s):

Teaching Hospital ◽

Clinical Information ◽

Redox Status ◽

G6pd Activity ◽

University Teaching ◽

Activity Levels ◽

Evaluation Tool ◽

Plateau State ◽

Glucose 6 Phosphate Dehydrogenase

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.

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Determination of Financial Competence in Consultation-Liaison Psychiatry

The Canadian Journal of Psychiatry ◽

10.1177/070674379303800905 ◽

1993 ◽

Vol 38 (9) ◽

pp. 595-598 ◽

Cited By ~ 6

Author(s):

Nadia D. Toffoli ◽

Nathan Herrmann

Keyword(s):

Retrospective Study ◽

Teaching Hospital ◽

University Teaching ◽

Surgical Patients ◽

Psychiatric Consultation ◽

Liaison Psychiatry ◽

Consultation Liaison Psychiatry ◽

Careful Documentation

The aging of our population will require physicians to become more aware of the issues surrounding the determination of financial competence. This retrospective study involved the review of 46 medical or surgical patients in a university teaching hospital that were referred to the psychiatric consultation-liaison team for assessment of financial competency. Charts were reviewed for completeness of documentation using suggested criteria for determination of financial competence. The study found that while many criteria were frequently documented, documentation was incomplete for important criteria, such as calculating abilities, judgement, the patient's appreciation of the consequences of financial competence, presence of delusions with regard to finances and the patient's awareness of debt. Concerns are expressed regarding a physician's ability to recall details pertaining to cases before a tribunal without complete and careful documentation. The importance of establishing formal criteria for the determination of financial competence is also discussed.

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Glucose-6- Phosphate Dehydrogenase Activity in Newborn in Jos: A Necessary Evaluation for Icteric Neonates

Journal of BioMedical Research and Clinical Practice ◽

10.46912/jbrcp.v2i42019.127 ◽

2019 ◽

Vol 2 (4) ◽

pp. 191-196

Author(s):

ED Jatau ◽

OB Toma ◽

OJ Egesie ◽

DO Damulak ◽

Z Ayuba ◽

...

Keyword(s):

Teaching Hospital ◽

Clinical Information ◽

Redox Status ◽

G6pd Activity ◽

University Teaching ◽

Activity Levels ◽

Evaluation Tool ◽

Plateau State ◽

Glucose 6 Phosphate Dehydrogenase

Red blood cell glucose-6-phosphate dehydrogenase (G6PD) is a key regulatory enzyme with the major role of meeting the cellular need for reductive biosynthesis and maintenance of redox status. G6PD deficiency is a common inherited enzyme defect associated with severe neonatal hyperbilirubinaemia that can result in permanent neurologic damage or death. This study was aimed at estimating the level of G6PD activity among icteric neonates to assess its usefulness in the evaluation of icteric neonates in Jos. One hundred and fifty icteric neonates (92 males and 58 females) whose parents consented were consecutively enrolled as they presented at the Special Care Baby Units (SCBU) of the Jos University Teaching Hospital (JUTH), Bingham University Teaching Hospital (BhUTH), and the Plateau State Specialist Hospital (PSSH), Jos. These subjects had their G6PD activity levels assayed using the Pointe Quantitative Diagnostic Kit (USA) while other relevant clinical information was obtained using a questionnaire. G6PD activity of the icteric neonates ranged between 0.54 and 24.18 IU/gHb with a mean of 8.02 ± 4.87 IU/gHb. Sixty-one (40.7 %), comprising 45 males and 16 female neonates were G6PD deficient with mean G6PD activity of 3.79 ± 1.37 IU/gHb while eighty-nine (59.3%) were G6PD normal with a mean G6PD activity of 10.92 ± 4.24 IU/gHb. G6PD activity in icteric neonates in Jos varies widely with a relatively high proportion of these neonates being G6PD deficient. Determination of G6PD activity in icteric neonates should therefore form an important evaluation tool for identification and intervention in those with the deficiency.

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Cord Blood Haematological Profiling Study: Predictive Markers of Neonatal Health Status at Birth in Anyigba, North Central Nigeria

International Journal of TROPICAL DISEASE & Health ◽

10.9734/ijtdh/2021/v42i930483 ◽

2021 ◽

pp. 33-39

Author(s):

Shedrack Egbunu Akor ◽

Dickson Achimugu Musa ◽

S. P. O. Akogu ◽

Akpa Matthew ◽

Adeyemi Alapo Funmilola ◽

...

Keyword(s):

Health Status ◽

Cord Blood ◽

Neonatal Mortality ◽

Umbilical Cord ◽

Teaching Hospital ◽

Umbilical Cord Blood ◽

University Teaching ◽

Haematological Parameters ◽

State University ◽

North Central

Background: Neonatal mortality refers to the death of a live-born babies within the first 28 days of life remains a global public health challenge. Cord blood being the medium of communication, transmission of nutrients and wastes between mothers and fetus can reflect the health status of baby at birth if properly utilized. Owing to multiple factors involved in neonatal mortality, this study used umbilical cord blood haematological parameters to ascertain the health status of neonates at birth, the aim of this study is to use umbilical cord blood haematological parameters for management of neonates at birth. Methodology: This research is a cross-sectional study carried out at the Departments of Obstetrics and Gynaecology and Medical Laboratory Department, Kogi State University Teaching Hospital, Anyigba, North Central Nigeria between January, and December, 2020. Cord blood from 164 babies delivered in Kogi State University Teaching Hospital, Grimard Catholic Hospital, and Amazing Grace Hospital between January and December, 2020 were analyzed for haematological parameters using Sysmex XP-300 automated haematology analyzer. The data obtained were expressed as mean ±standard deviation using SPSS statistical software, version 23.0. The indicator level of statistical significance was set at p<0.05. Results: The results showed significant increase (p<0.05) of WBC, RBC, MCV, MCH and MCHC in unstable babies compared to the stable babies, significant decrease (p<0.05) in the platelets, neutrophil and mixed among unstable babies compared to the stable babies, but no significant difference in PCV, haemoglobin and lymphocyte counts of both stable and unstable babies. The results also demonstrated 25 deaths per 1000 live newborn neonates within 48hour during the period of study. Conclusion: This study shows that cord blood haematological parameters at birth can be used to ascertain the health status of neonates.

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