Selective transitional zone sampling approach versus random biopsy in cases with malignant liver masses: Is there any superiority?

Objectives: To investigate associations of the transitional zone volume (TZV) with intraprostatic chronic inflammatory infiltrate (CII) and prostate cancer (PCa) risk in patients undergoing a first random biopsy set. Materials and Methods: The study included a homogenous population of 596 patients. The volume of the prostate and TZV were separately measured. Independent associations were investigated by multivariate logistic regression analysis. Results: The median TZV was 18 ml, CII was detected in 157 cases (26.3%), and PCa was present in 292 patients (49%). TZV was the only independent clinical factor associated with CII risk (OR = 1.014). After correcting for CII (OR = 0.276; p < 0.0001), independent factors associated with PCa risk included age (OR = 1.066), prostate specific antigen (OR = 1.177), TZV (OR = 0.919), and an abnormal digital rectal exam (OR = 2.024). Conclusion: In a patient population undergoing a first random prostate biopsy set because of suspected cancer, independent associations were detected among TZV, CII, and PCa. The association between TZV and CII was direct, but the relation between TZV and PCa was inverse. The measurement of the volume of the transitional zone was a useful parameter for evaluating chronic intraprostatic inflammation and PCa risk.

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Prostate Volume Index Stratified Prostate Cancer Risk in Patients Elected to a First Random Biopsy Set

Tumori Journal ◽

10.5301/tj.5000607 ◽

2017 ◽

Vol 103 (4) ◽

pp. 374-379 ◽

Cited By ~ 5

Author(s):

Antonio B. Porcaro ◽

Paolo Corsi ◽

Nicolò de Luyk ◽

Marco Sebben ◽

Alessandro Tafuri ◽

...

Keyword(s):

Prostate Cancer ◽

Goodness Of Fit ◽

Prostate Volume ◽

Digital Rectal Examination ◽

Prostate Cancer Risk ◽

Peripheral Zone ◽

Transitional Zone ◽

Volume Index ◽

Multivariate Logistic Regression Model ◽

Random Biopsy

Objective To investigate prostate volume index (PVI), defined as the ratio of volume of the transitional zone on that of the peripheral zone, as a factor stratifying prostate cancer (PCA) risk in patients elected to a first random biopsy set. Methods The study evaluated 596 patients who were elected to a first random biopsy set because of suspected PCA in a period between September 2010 and September 2015. Prostate volume index was dichotomized to PVI ≤1 vs PVI >1. The multivariate logistic regression model investigated clinical factors with dichotomized PVI associating with PCA. Results The detection rate of PCA was 49%. The dichotomized PVI >1 stratified PCA risk (odds ratio [OR] 0.455; p<0.0001) beyond age (OR 1.062; p<0.0001), PSA (OR 1.167; p<0.0001), PV (OR 0.957; p<0.0001), and abnormal digital rectal examination (OR 2.094; p<0.0001). The goodness of fit statistics assessed model efficacy. Conclusions A large cohort of patients elected to a first random biopsy set had PCA risk stratified by dichotomized PVI beyond other clinical independent factors. Confirmatory studies are required.

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Multicommutation in flow analysis. Part 3. Spectrophotometric kinetic determination of creatinine in urine exploiting a novel zone sampling approach

Analytica Chimica Acta ◽

10.1016/0003-2670(95)00102-6 ◽

1995 ◽

Vol 310 (3) ◽

pp. 447-452 ◽

Cited By ~ 27

Author(s):

Alberto N. Araújo ◽

JoséL.F.Costa Lima ◽

Boaventura F. Reis ◽

Elias A.G. Zagatto

Keyword(s):

Flow Analysis ◽

Kinetic Determination ◽

Zone Sampling ◽

Sampling Approach

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Analysis and lattice imaging of a transitional event on garnets

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100108490 ◽

1978 ◽

Vol 36 (1) ◽

pp. 270-271

Author(s):

J.Y. Laval

Keyword(s):

Yttrium Iron Garnet ◽

Reciprocal Lattice ◽

Transitional Zone ◽

Lattice Imaging ◽

Yttrium Iron ◽

X Ray ◽

Ionic Process ◽

The Matrix ◽

High Resolution Technique ◽

Iron Garnet

The exsolution of magnetite from a substituted Yttrium Iron Garnet, containing an iron excess may lead to a transitional event. This event is characterized hy the formation of a transitional zone at the center of which the magnetite nucleates (Fig.1). Since there is a contrast between the matrix and these zones and since selected area diffraction does not show any difference between those zones and the matrix in the reciprocal lattice, it is of interest to analyze the structure of the transitional zones.By using simultaneously different techniques in electron microscopy, (oscillating crystal method microdiffraction and X-ray microanalysis)one may resolve the ionic process corresponding to the transitional event and image this event subsequently by high resolution technique.

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