Expanding community support in genetic diversity management

AbstractThe pepper-bark tree (Warburgia salutaris) is one of the most highly valued medicinal plant species worldwide. Native to southern Africa, this species has been extensively harvested for the bark, which is widely used in traditional health practices. Illegal harvesting coupled with habitat degradation has contributed to fragmentation of populations and a severe decline in its distribution. Even though the species is included in the IUCN Red List as Endangered, genetic data that would help conservation efforts and future re-introductions are absent. We therefore developed new molecular markers to understand patterns of genetic diversity, structure, and gene flow of W. salutaris in one of its most important areas of occurrence (Mozambique). In this study, we have shown that, despite fragmentation and overexploitation, this species maintains a relatively high level of genetic diversity supporting the existence of random mating. Two genetic groups were found corresponding to the northern and southern locations. Our study suggests that, if local extinctions occurred in Mozambique, the pepper-bark tree persisted in sufficient numbers to retain a large proportion of genetic diversity. Management plans should concentrate on maintaining this high level of genetic variability through both in and ex-situ conservation actions.

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Genetic Diversity Management of Moroccan Captive-Bred Houbaras

Open Journal of Applied Sciences ◽

10.4236/ojapps.2018.82004 ◽

2018 ◽

Vol 08 (02) ◽

pp. 47-61

Author(s):

Amal Korrida ◽

Brahim Benameur ◽

Karim Filali ◽

Sami Jamil Jadallah

Keyword(s):

Genetic Diversity ◽

Diversity Management ◽

Genetic Diversity Management

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Design and performance of a bovine 200 k SNP chip developed for endangered German Black Pied cattle (DSN)

BMC Genomics ◽

10.1186/s12864-021-08237-2 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Guilherme B. Neumann ◽

Paula Korkuć ◽

Danny Arends ◽

Manuel J. Wolf ◽

Katharina May ◽

...

Keyword(s):

Genetic Diversity ◽

Association Studies ◽

Bos Indicus ◽

Diversity Management ◽

Whole Genome Sequencing Data ◽

General Interest ◽

Whole Genome ◽

Sequencing Data ◽

Snp Chip ◽

Selection Of

Abstract Background German Black Pied cattle (DSN) are an endangered dual-purpose breed which was largely replaced by Holstein cattle due to their lower milk yield. DSN cattle are kept as a genetic reserve with a current herd size of around 2500 animals. The ability to track sequence variants specific to DSN could help to support the conservation of DSN’s genetic diversity and to provide avenues for genetic improvement. Results Whole-genome sequencing data of 304 DSN cattle were used to design a customized DSN200k SNP chip harboring 182,154 variants (173,569 SNPs and 8585 indels) based on ten selection categories. We included variants of interest to DSN such as DSN unique variants and variants from previous association studies in DSN, but also variants of general interest such as variants with predicted consequences of high, moderate, or low impact on the transcripts and SNPs from the Illumina BovineSNP50 BeadChip. Further, the selection of variants based on haplotype blocks ensured that the whole-genome was uniformly covered with an average variant distance of 14.4 kb on autosomes. Using 300 DSN and 162 animals from other cattle breeds including Holstein, endangered local cattle populations, and also a Bos indicus breed, performance of the SNP chip was evaluated. Altogether, 171,978 (94.31%) of the variants were successfully called in at least one of the analyzed breeds. In DSN, the number of successfully called variants was 166,563 (91.44%) while 156,684 (86.02%) were segregating at a minor allele frequency > 1%. The concordance rate between technical replicates was 99.83 ± 0.19%. Conclusion The DSN200k SNP chip was proved useful for DSN and other Bos taurus as well as one Bos indicus breed. It is suitable for genetic diversity management and marker-assisted selection of DSN animals. Moreover, variants that were segregating in other breeds can be used for the design of breed-specific customized SNP chips. This will be of great value in the application of conservation programs for endangered local populations in the future.

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Development of national animal genetic resource programs

Reproduction Fertility and Development ◽

10.1071/rd03075 ◽

2004 ◽

Vol 16 (2) ◽

pp. 27 ◽

Cited By ~ 26

Author(s):

H. D. Blackburn

Keyword(s):

Information Exchange ◽

Genetic Resource ◽

Diversity Management ◽

Ex Situ ◽

Critical Element ◽

Emergency Situations ◽

Food And Agriculture ◽

Animal Genetic Resource ◽

Genetic Diversity Management

Globally, animal genetic resources are contracting due to economic forces. As a result, during the 1990s there was a dramatic increase in national animal genetic resource activities. Many national programmes were initiated and the Food and Agriculture Organisation of the United Nations played a prominent role in coalescing national actions. Nationally, programmes have been initiated that comprise of in situ, ex situ and information-exchange efforts. A critical element to national conservation efforts is the development of cryopreserved collections of germplasm. Several countries have initiated substantial multispecies collections of cryopreserved germplasm. The selection of animals within breeds of interest is an important consideration in building cryopreserved collections. Animal selection should be based on a lack of genetic relationship, with sufficient numbers of animals to ensure the capture of rare alleles. Major issues facing repository development and genetic conservation are: (1) that all breeds are in need of genetic diversity management; (2) a better understanding of in situ breed population dynamics is needed; and (3) the concept that repository collections can be used by a broad range of clientele across time as well as during emergency situations.

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Shared Responsibilities for Full Participation in Society: Planning Further Integration of the ICF Into AAC

Perspectives of the ASHA Special Interest Groups ◽

10.1044/persp1.sig12.83 ◽

2016 ◽

Vol 1 (12) ◽

pp. 83-93 ◽

Cited By ~ 1

Author(s):

Mary Blake Huer ◽

Travis T. Threats

Keyword(s):

Environmental Factors ◽

Augmentative And Alternative Communication ◽

Functional Limitations ◽

Community Support ◽

World Health ◽

International Classification Of Functioning ◽

Personal Factors ◽

Social Service Agencies ◽

Persons With Disabilities ◽

Full Participation

The World Health Organization's (WHO's) 2001 International Classification of Functioning Disability and Health (ICF) has as one of its central tenets the full inclusion of persons with disabilities in society. It acknowledges the need for medical and rehabilitation intervention in its biopscychosocial framework. However, the WHO realizes that society must do its part to facilitate this full participation and empowerment. Persons with complex communication needs (PWCCN) often need augmentative and alternative communication (AAC) in order to express themselves. However, in order to access and successfully use AAC, PWCCN need access to the necessary AAC devices and services, as well as a willing society to interact with them as full contributing members of society. The factors outside of a person's specific physical and/or cognitive functional limitations are addressed in the ICF via the Personal and Environmental Factors. Personal Factors include the individual's personality traits, lifestyle, experiences, social/educational/professional background, race, gender, and age. Environmental Factors include community support systems, social service agencies, governments, social networks, and those persons that interact with the PWCCN. This article addresses the sociopolitical influences on PWCCN and their functioning from a human rights perspective. The necessary introspective role of speech-language pathologists in this process is explored.

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