Mild cognitive impairment and prospective memory: translating the evidence into neuropsychological practice

Author(s):  
Glynda J. Kinsella ◽  
Kerryn E. Pike ◽  
Marina G. Cavuoto ◽  
Stephen D. Lee
2009 ◽  
Vol 15 (3) ◽  
pp. 407-415 ◽  
Author(s):  
STELLA KARANTZOULIS ◽  
ANGELA K. TROYER ◽  
JILL B. RICH

AbstractIndividuals with amnestic mild cognitive impairment (aMCI) often complain of difficulty remembering to carry out intended actions, consistent with findings of impaired prospective memory (PM) in this population. In this study, individuals with aMCI (N = 27) performed worse than healthy controls (N = 27) on the Memory for Intentions Screening Test (Raskin, 2004), including on time- and event-based subscales, and recognition of the intentions. The aMCI participants made more errors overall, but the proportion of the various error types did not differ between the two groups. Across all error types, both groups made more retrospective than prospective errors, especially on event-based PM tasks. Overall, the findings suggest that PM impairment in aMCI is associated with deficient cue detection involving both automatic (as in event-based tasks) and more strategic detection (as in time-based tasks) processes. These difficulties are likely due to a combination of problematic retrospective episodic memory (e.g., reduced encoding and/or consolidation of cue–intention pairings) and executive functions (e.g., decreased self-initiation, attention switching, and/or inhibition on memory tasks). Formal assessment of PM may help characterize the nature of the memory impairment among individuals with aMCI in clinical neuropsychological evaluations. (JINS, 2009, 15, 407–415.)


2010 ◽  
Vol 24 (3) ◽  
pp. 327-335 ◽  
Author(s):  
Alberto Costa ◽  
Roberta Perri ◽  
Laura Serra ◽  
Francesco Barban ◽  
Ilaria Gatto ◽  
...  

2009 ◽  
Vol 15 (1) ◽  
pp. 154-159 ◽  
Author(s):  
ALBERTO BLANCO-CAMPAL ◽  
ROBERT F. COEN ◽  
BRIAN A. LAWLOR ◽  
JOSEPH B. WALSH ◽  
TERESA E. BURKE

AbstractWe investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely used retrospective memory (RM) tests (Rivermead Paragraph Recall Test and CERAD-Word List Test), when detecting mild cognitive impairment of suspected Alzheimer’s disease etiology (MCI-AD) (N = 19) from normal controls (NC) (N = 21). Statistical analyses showed high discriminatory capacity of the PM task for detecting MCI-AD. The Non-Specific-Non-Salient condition proved particularly useful in detecting MCI-AD, possibly reflecting the difficulty of the task, requiring more strategic attentional resources to monitor for the PM cue. With a cutoff score of <4/10, the Non-Specific-Non-Salient condition achieved a sensitivity = 84%, and a specificity = 95%, superior to the most discriminative RM test used (CERAD-Total Learning: sensitivity = 83%; specificity = 76%). Results suggest that PM is an early sign of memory failure in MCI-AD and may be a more pronounced deficit than retrospective failure, probably reflecting the greater self-initiated retrieval demands involved in the PM task used. Limitations include the relatively small sample size, and the use of a convenience sample (i.e. memory clinic attenders and healthy active volunteers), reducing the generalizability of the results, which should be regarded as preliminary. (JINS, 2009, 15, 154–159.)


2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Winter Olmos ◽  
Jacob Moore ◽  
Sarah Saravia ◽  
Jasmin C Moreno ◽  
Chandler Donny ◽  
...  

Author(s):  
Ariane Lajeunesse ◽  
Marie-Julie Potvin ◽  
Véronique Labelle ◽  
Sven Joubert ◽  
Isabelle Rouleau

2011 ◽  
Vol 5 (2) ◽  
pp. 64-68 ◽  
Author(s):  
Lívia Spíndola ◽  
Sonia Maria Dozzi Brucki

Abstract Prospective memory (PM) is defined as remembering to carry out intended actions at an appropriate point in the future, and can be categorized into three types of situation: time-, event-, and activity-based tasks. PM involves brain structures such as frontal and medial temporal cortices. The aim of this study was to review the currently available literature on PM in Alzheimer's disease and Mild Cognitive Impairment patients. We performed a search on Pubmed, Medline, ScieLO, LILACS and the Cochrane Library electronic databases from January 1990 to December 2010. The key terms used were: prospective memory, memory for intentions, delayed memory and memory for future actions, separately and also combined with the search terms dementia, Alzheimer's disease and Mild Cognitive Impairment. Both patient groups showed significant impairment in PM. Further studies are needed to verify the accuracy of PM tasks as an early marker of mild cognitive impairment, and initial dementia.


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