scholarly journals Latent ovarian stimulation in the management of infertile patients with hypogonadotropic hypogonadism

2021 ◽  
Vol 12 (Suppl 3) ◽  
Keyword(s):  
Ovarian Stimulation ◽  
Hypogonadotropic Hypogonadism ◽  
Infertile Patients

Comparison of embryonic aneuploidy rates in young (<35 years) infertile patients following three different ovarian stimulation protocols

2007 ◽  
Vol 88 ◽  
pp. S232 ◽  
Author(s):  
Z.P. Nagy ◽  
T. Elliott ◽  
T. Callaghan ◽  
G. Wright ◽  
D. Shapiro ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Infertile Patients

Controlled ovarian stimulation and IVF pregnancy in a trisomy X carrier with associated hypogonadotropic hypogonadism

2017 ◽  
Vol 33 (10) ◽  
pp. 763-765 ◽  
Author(s):  
Claudia Massarotti ◽  
Patrizia Fiorio ◽  
Roberto Gastaldi ◽  
Lucia Rosaia De Santis ◽  
Daniela Pastorino ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Hypogonadotropic Hypogonadism ◽  
Controlled Ovarian Stimulation ◽  
Trisomy X

scholarly journals Ovarian reserve parameters and response to controlled ovarian stimulation in infertile patients

2019 ◽  
Vol 35 (4) ◽  
Author(s):  
Qurat Aman Siddiqui ◽  
Sagheera Anjum ◽  
Fatima Zahra ◽  
Sarim Muhammad Yousuf
Keyword(s):  
Ovarian Reserve ◽  
Ovarian Stimulation ◽  
Cross Sectional Study ◽  
Controlled Ovarian Stimulation ◽  
P Value ◽  
Strongly Correlated ◽  
Cross Sectional ◽  
Creative Commons ◽  
Infertile Patients

Objective: To determine the ovarian reserve parameters in patients presenting for IVF and intracytoplasmic sperm injection (ICSI) treatment and its association with the number of follicles retrieved and number of oocyte retrieved and fertilized. Methods: A retrospective cross sectional study was conducted at Australian Concept Infertility Medical Centre from January 2017 to August 2017. Around 120 couples presenting to infertility clinics selected for IVF and ICSI with Females (25-45) had their FSH, AMH and AFC done. After ovulation induction, its response was determined by number of follicles retrieved, quality of oocytes retrieved or fertilized and inseminated. SPSS version 20 was used for the purpose of data analysis.  Results: The median age of the patients was 34 (29-38) years. A moderate negative correlation of age and FSH levels was observed with quality of oocytes, Number of oocyte inseminated, number of oocyte fertilized and number of follicle restored. However, a positive correlation of AMH and AFC levels were found with quality of oocytes, Number of oocyte inseminated, number of oocyte fertilized and number of follicle restored. The correlation of AMH levels with number of oocyte inseminated (rho 0.729, p-value <0.001), number of oocyte fertilized (rho 0.721, <0.001) and number of follicle restored (rho 0.723, p-value <0.001) were found strongly correlated. Conclusion: Our study concluded that AMH and AFC have a strong correlation with number of follicles restored and number of oocytes retrieved whereas FSH and age has a weak correlation with the number of follicles restored and number of oocytes retrieved. doi: https://doi.org/10.12669/pjms.35.4.753 How to cite this:Siddiqui QA, Anjum S, Zahra F, Yousuf SM. Ovarian reserve parameters and response to controlled ovarian stimulation in infertile patients. Pak J Med Sci. 2019;35(4):---------.   doi: https://doi.org/10.12669/pjms.35.4.753 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals Type and dose of gonadotropins in poor ovarian responders: does it matter?

2021 ◽  
Vol 15 ◽  
pp. 263349412110242
Author(s):  
Liese Boudry ◽  
Annalisa Racca ◽  
Herman Tournaye ◽  
Christophe Blockeel
Keyword(s):  
In Vitro Fertilization ◽  
Ovarian Stimulation ◽  
Ovarian Response ◽  
Oocyte Donation ◽  
Reproductive Technology ◽  
Poor Ovarian Response ◽  
Vitro Fertilization ◽  
Poor Ovarian Responders ◽  
Infertile Patients

Infertile patients with a diminished ovarian reserve, also referred to as poor ovarian responders, constitute a substantial and increasing population of patients undergoing in vitro fertilization. The management of patients with poor ovarian response is still a controversial issue. Almost a century has passed since the introduction of the first gonadotropin. A broad collection of urinary and recombinant gonadotropins, including biosimilars, is commercially available now. Despite great advances in assisted reproductive technology, there remains uncertainty about the optimal treatment regimen for ovarian stimulation in poor ovarian responders. Although oocyte donation is the most successful and ultimate remedy for poor ovarian responders, most patients persist on using their own oocytes in several attempts, to achieve the desired pregnancy. The aim of this review is twofold: first, to provide an overview of the commercially available gonadotropins and summarize the available evidence supporting the use of one or another for ovarian stimulation in poor ovarian responders, and second, to address the controversies on the dosage of gonadotropins for this specific in vitro fertilization population.

Efficacy of Follitropin-A (Gonal-F) Versus Follitropin-B (Puregon) for Controlled Ovarian Stimulation in Women Undergoing IVF

2019 ◽  
Vol 10 (04) ◽  
pp. 681-685
Author(s):  
Hayder Abdulhafedh Kurji ◽  
Qutaiba Ahmed Al Khames Aga ◽  
Myasar Jasim Mohammed Al- Taie ◽  
Yazan A Bataineh ◽  
Mohammed Khudhair Hasan ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnancy Rate ◽  
Ovarian Stimulation ◽  
Infertility Treatment ◽  
Clinical Pregnancy ◽  
Recombinant Fsh ◽  
Vitro Fertilization ◽  
High Pregnancy Rate ◽  
Infertile Patients

The purpose of this study was to compare the efficacy of two recombinant FSH on pregnancy rates in infertile patients. Material and Methods: between 2015-2017, 387 females intended to have in vitro fertilization (IVF) for infertility treatment (226 patients use Gonal-F and 161 using Puregon. Results: Serum E2 concentration at hCG time was higher with Follitropin-a treated patients, and a larger number of retrieved oocyte result in a large number of the transferred embryo, and high pregnancy rate than Follitropin-b treated patients. Conclusions: Gonal-F (Follitropin-a) is associated with a potential stimulatory effect on ovaries. Puregon (Follitropin-b) was associated with a lower clinical pregnancy rate (PR). E2 level 5-7 days after stimulation can be used as an indicator of the success of IVF.

scholarly journals Recombinant luteinizing hormone supplementation in assisted reproductive technology: a review of literature

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Maryam Eftekhar ◽  
Nasim Tabibnejad
Keyword(s):  
Luteinizing Hormone ◽  
Assisted Reproductive Technology ◽  
Ovarian Stimulation ◽  
Ovarian Function ◽  
Hypogonadotropic Hypogonadism ◽  
Poor Responder ◽  
Reproductive Technology ◽  
Main Role ◽  
Main Body ◽  
Art Outcome

Abstract Background Luteinizing hormone (LH) has the main role in ovarian function in both natural and artificial cycles. A normal LH concentration during controlled ovarian hyperstimulation is positively correlated to the number and quality of retrieved oocytes and resulting embryos. Main body of the abstract In this study, we reviewed whether rLH administration, adjunct to the ovarian stimulation regimen, could improve clinical outcomes. The literature review showed that rLH supplementation improves assisted reproductive technology (ART) outcomes among women with hypogonadotropic hypogonadism, and hyporesponsive women to follicle-stimulating hormone monotherapy. Besides, rLH supplementation has advantages for poor responder women 36–39 years of age. Even though the data suggested no priority regarding the LH source for improving ART outcome, women with different LH polymorphisms who did not respond similarly to ovarian stimulation may benefit from adjuvant rLH therapy. Conclusion rLH usage for improving ART outcome should be scrutinized via well-designed studies considering the subgroups of infertile women who benefit the most from rLH adjuvant therapy, the type of ovarian stimulation protocol to which rLH would be added, and also the exact dosage, as well as the proper timing (during or prior to a cycle).

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