scholarly journals The Evaluation of Primary Lesion and Axillary Metastasis in Breast Carcinoma By 18F-FDG PET/CT

2015 ◽  
Vol 06 (01) ◽  
Keyword(s):  
Breast Carcinoma ◽  
Fdg Pet ◽  
Primary Lesion ◽  
Axillary Metastasis ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

The feasibility of using 18F-FDG-PET/CT in patients with mucinous breast carcinoma

2018 ◽  
Vol 39 (11) ◽  
pp. 1033-1038 ◽  
Author(s):  
Tomoyuki Fujioka ◽  
Kazunori Kubota ◽  
Yuka Kikuchi ◽  
Junichi Tsuchiya ◽  
Ukihide Tateishi ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Mucinous Breast Carcinoma

scholarly journals 18F-FDG Pet Parameters and Radiomics Features Analysis in Advanced Nsclc Treated with Immunotherapy as Predictors of Therapy Response and Survival

Cancers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1163 ◽  
Author(s):  
Giulia Polverari ◽  
Francesco Ceci ◽  
Valentina Bertaglia ◽  
Maria Lucia Reale ◽  
Osvaldo Rampado ◽  
...  
Keyword(s):  
Disease Progression ◽  
Fdg Pet ◽  
Tumor Volume ◽  
Advanced Nsclc ◽  
Therapy Response ◽  
Primary Lesion ◽  
Line Therapy ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Objectives: (1.1) to evaluate the association between baseline 18F-FDG PET/CT semi-quantitative parameters of the primary lesion with progression free survival (PFS), overall survival (OS) and response to immunotherapy, in advanced non-small cell lung carcinoma (NSCLC) patients eligible for immunotherapy; (1.2) to evaluate the application of radiomics analysis of the primary lesion to identify features predictive of response to immunotherapy; (1.3) to evaluate if tumor burden assessed by 18F-FDG PET/CT (N and M factors) is associated with PFS and OS. Materials and Methods: we retrospectively analyzed clinical records of advanced NCSLC patients (stage IIIb/c or stage IV) candidate to immunotherapy who performed 18F-FDG PET/CT before treatment to stage the disease. Fifty-seven (57) patients were included in the analysis (F:M 17:40; median age = 69 years old). Notably, 38/57 of patients had adenocarcinoma (AC), 10/57 squamous cell carcinoma (SCC) and 9/57 were not otherwise specified (NOS). Overall, 47.4% patients were stage IVA, 42.1% IVB and 8.8% IIIB. Immunotherapy was performed as front-line therapy in 42/57 patients and as second line therapy after chemotherapy platinum-based in 15/57. The median follow up after starting immunotherapy was 10 months (range: 1.5–68.6). Therapy response was assessed by RECIST 1.1 criteria (CT evaluation every 4 cycles of therapy) in 48/57 patients or when not feasible by clinical and laboratory data (fast disease progression or worsening of patient clinical condition in nine patients). Radiomics analysis was performed by applying regions of interest (ROIs) of the primary tumor delineated manually by two operators and semi-automatically applying a threshold at 40% of SUVmax. Results: (1.1) metabolic tumor volume (MTV) (p = 0.028) and total lesion glycolysis (TLG) (p = 0.035) were significantly associated with progressive vs. non-progressive disease status. Patients with higher values of MTV and TLG had higher probability of disease progression, compared to those patients presenting with lower values. SUVmax did not show correlation with PD status, PFS and OS. MTV (p = 0.027) and TLG (p = 0.022) also resulted in being significantly different among PR, SD and PD groups, while SUVmax was confirmed to not be associated with response to therapy (p = 0.427). (1.2) We observed the association of several radiomics features with PD status. Namely, patients with high tumor volume, TLG and heterogeneity expressed by “skewness” and “kurtosis” had a higher probability of failing immunotherapy. (1.3) M status at 18F-FDG PET/CT was significantly associated with PFS (p = 0.002) and OS (p = 0.049). No significant associations were observed for N status. Conclusions: 18F-FDG PET/CT performed before the start of immunotherapy might be an important prognostic tool able to predict the disease progression and response to immunotherapy in patients with advanced NSCLC, since MTV, TLG and radiomics features (volume and heterogeneity) are associated with disease progression.

scholarly journals Dual-Time 18F-FDG PET/CT Imaging in Initial Locoregional Staging of Breast Carcinoma: Comparison with Conventional Imaging and Pathological Prognostic Factors

2016 ◽  
Vol 78 (5) ◽  
pp. 382-389 ◽  
Author(s):  
Aynur Ozen ◽  
Serdar Altinay ◽  
Ozgul Ekmekcioglu ◽  
Ramazan Albayrak ◽  
Ali Muhammedoglu ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Breast Carcinoma ◽  
Fdg Pet ◽  
Ct Imaging ◽  
Conventional Imaging ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Locoregional Staging

scholarly journals 212P The role of 18F-FDG PET-CT with specific breast protocol as a prognostic biomarker of invasive breast carcinoma

2020 ◽  
Vol 31 ◽  
pp. S326
Author(s):  
C.C. Tajima ◽  
A.G.V. Bitencourt ◽  
E.F. Marques ◽  
E.P.L. Nóbrega ◽  
R.A. De Mello
Keyword(s):  
Breast Carcinoma ◽  
Fdg Pet ◽  
Prognostic Biomarker ◽  
Invasive Breast Carcinoma ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

18F-FDG PET/CT Appearance of Metastatic Brachial Plexopathy Involving Epidural Space From Breast Carcinoma

2012 ◽  
Vol 37 (10) ◽  
pp. e263-e264 ◽  
Author(s):  
Linh Ho ◽  
Robert Henderson ◽  
Thang Luong ◽  
Silva Malkhassian ◽  
Heidi Wassef
Keyword(s):  
Breast Carcinoma ◽  
Epidural Space ◽  
Fdg Pet ◽  
Brachial Plexopathy ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Isolated splenic metastases of breast carcinoma detected with 18F-FDG PET/CT

2013 ◽  
Vol 1 (2) ◽  
pp. 65-68
Author(s):  
Pushpa latha ◽  
Praveen Singa ◽  
Amber Papalkar ◽  
Raghu Ram P
Keyword(s):  
Breast Carcinoma ◽  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  
Splenic Metastases ◽  
Fdg Pet Ct

Unsuspected Uterine Metastasis of Breast Carcinoma Diagnosed by 18F-FDG PET/CT

2013 ◽  
Vol 38 (11) ◽  
pp. e441-e442 ◽  
Author(s):  
Jose Muñoz-Iglesias ◽  
Jon Uña-Gorospe ◽  
Ana Allende-Riera ◽  
Marta De Sequera-Rahola ◽  
Carlos Cárdenas-Negro
Keyword(s):  
Breast Carcinoma ◽  
Fdg Pet ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct
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