Gd-EOB-DTPA based magnetic resonance imaging for predicting liver response to portal vein embolization

Purpose.To investigate the liver volume change and the potential of early evaluation by contrast-enhanced magnetic resonance imaging (MRI) using gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) after portal vein embolization (PVE).Materials and Methods.Retrospective evaluations of computed tomography (CT) volumetry of total liver and nonembolized areas were performed before and 3 weeks after PVE in 37 cases. The percentage of future liver remnant (%FLR) and the change ratio of %FLR (%FLR ratio) were calculated. Prospective evaluation of signal intensities (SIs) was performed to estimate the role of Gd-EOB-DTPA-enhanced MRI as a predictor of hypertrophy in 16 cases. The SI contrast between embolized and nonembolized areas was calculated 1 week after PVE. The change in SI contrast before and after PVE (SI ratio) was also calculated in 11 cases.Results.%FLR ratio significantly increased, and SI ratio significantly decreased (bothP<0.01). There were significant negative correlations between %FLR and SI contrast and between %FLR and SI ratio (bothP<0.01).Conclusion.Hypertrophy in the nonembolized area after PVE was indicated by CT volumetry, and measurement of SI contrast and SI ratio in Gd-EOB-DTPA-enhanced MRI early after PVE may be useful to predict the potential for hepatic hypertrophy.

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Preoperative Estimation of Future Remnant Liver Function Following Portal Vein Embolization Using Relative Enhancement on Gadoxetic Acid Disodium-Enhanced Magnetic Resonance Imaging

Korean Journal of Radiology ◽

10.3348/kjr.2015.16.3.523 ◽

2015 ◽

Vol 16 (3) ◽

pp. 523 ◽

Cited By ~ 10

Author(s):

Yozo Sato ◽

Shigeru Matsushima ◽

Yoshitaka Inaba ◽

Tsuyoshi Sano ◽

Hidekazu Yamaura ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Liver Function ◽

Portal Vein ◽

Portal Vein Embolization ◽

Remnant Liver ◽

Future Remnant Liver ◽

Resonance Imaging ◽

Remnant Liver Function ◽

Gadoxetic Acid Disodium

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MRI-Based Quantitation of Hepatic Steatosis Does Not Predict Hypertrophy Rate after Portal Vein Embolization in Patients with Colorectal Liver Metastasis and Normal to Moderately Elevated Fat Fraction

Journal of Clinical Medicine ◽

10.3390/jcm10092003 ◽

2021 ◽

Vol 10 (9) ◽

pp. 2003

Author(s):

Lea Hitpass ◽

Iakovos Amygdalos ◽

Paul Sieben ◽

Vanessa Raaff ◽

Sven Lang ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Colorectal Cancer ◽

Growth Rate ◽

Magnetic Resonance ◽

Portal Vein ◽

Portal Vein Embolization ◽

Resonance Imaging ◽

Kinetic Growth ◽

History Of ◽

Fat Fraction

The aim of this study was to correlate the pre-procedural magnetic-resonance-imaging-based hepatic fat fraction (hFF) with the degree of hypertrophy after portal vein embolization (PVE) in patients with colorectal cancer liver metastases (CRCLM). Between 2011 November and 2020 February, 68 patients with CRCLM underwent magnetic resonance imaging (MRI; 1.5 Tesla) of the liver before PVE. Using T1w chemical shift imaging (DUAL FFE), the patients were categorized as having a normal (<5%) or an elevated (>5%) hFF. The correlation of hFF, age, gender, initial tumor mass, history of chemotherapy, degree of liver hypertrophy, and kinetic growth rate after PVE was investigated using multiple regression analysis and Spearman’s test. A normal hFF was found in 43/68 patients (63%), whereas 25/68 (37%) patients had an elevated hFF. The mean hypertrophy and kinetic growth rates in patients with normal vs. elevated hFF were 24 ± 31% vs. 28 ± 36% and 9 ± 9 % vs. 8 ± 10% (p > 0.05), respectively. Spearman’s test showed no correlation between hFF and the degree of hypertrophy (R = −0.04). Multivariable analysis showed no correlation between hFF, history of chemotherapy, age, baseline tumor burden, or laterality of primary colorectal cancer, and only a poor inverse correlation between age and kinetic growth rate after PVE. An elevated hFF in a pre-procedural MRI does not correlate with the hypertrophy rate after PVE and should therefore not be used as a contraindication to the procedure in patients with CRCLM.

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POSTPRANDIAL FLOW MEASUREMENTS OF THE MESENTERIC ARTERIES AND PORTAL VEIN USING MAGNETIC RESONANCE IMAGING: A PILOT STUDY

10.26226/morressier.57c5383fd462b80296c9b874 ◽

2016 ◽

Author(s):

Louisa van Dijk

Keyword(s):

Magnetic Resonance Imaging ◽

Pilot Study ◽

Magnetic Resonance ◽

Portal Vein ◽

Mesenteric Arteries ◽

Resonance Imaging ◽

Flow Measurements

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Ultrasound and magnetic resonance imaging findings in Schistosomiasis mansoni: expanded gallbladder fossa and fatty hilum signs

Revista da Sociedade Brasileira de Medicina Tropical ◽

10.1590/s0037-86822012005000008 ◽

2012 ◽

Vol 45 (4) ◽

pp. 500-504 ◽

Cited By ~ 6

Author(s):

Luciana Cristina dos Santos Silva ◽

Luciene Mota Andrade ◽

Ivie Braga de Paula ◽

Leonardo Campos de Queiroz ◽

Carlos Maurício Figueiredo Antunes ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Portal Vein ◽

Wall Thickening ◽

Main Portal Vein ◽

Fat Tissue ◽

Resonance Imaging ◽

Mri Findings ◽

Schistosomiasis Mansoni ◽

Gallbladder Fossa

INTRODUCTION: There is no study relating magnetic resonance imaging (MRI) to ultrasound (US) findings in patients with Schistosomiasis mansoni. Our aim was to describe MRI findings inpatients with schistosomal liver disease identified by US. METHODS: Fifty-four patients (mean age 41.6±13.5years) from an area endemic for Schistosomiasis mansoni were selected for this study.All had US indicating liver schistosomal fibrosis and were evaluated with MRI performed witha 1.5-T superconducting magnet unit (Sigma). RESULTS: Forty-seven (87%) of the 54 patientsshowing signs of periportal fibrosis identified through US investigation had confirmed diagnosesby MRI. In the seven discordant cases (13%), MRI revealed fat tissue filling in the hilar periportalspace where US indicated isolated thickening around the main portal vein at its point of entryto the liver. We named this the fatty hilum sign. One of the 47 patients with MRI evidence ofperiportal fibrosis had had his gallbladder removed previously. Thirty-five (76.1%) of the other46 patients had an expanded gallbladder fossa filled with fat tissue, whereas MRI of the remainingeleven showed pericholecystic signs of fibrosis. CONCLUSIONS: Echogenic thickening of thegallbladder wall and of the main portal vein wall heretofore attributed to fibrosis were frequentlyidentified as fat tissue in MRI. However, the gallbladder wall thickening shown in US (expandedgallbladder fossa in MRI) is probably secondary to combined hepatic morphologic changes inschistosomiasis, representing severe liver involvement.

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