Basal Tako-Tsubo cardiomyopathy: an uncommon case of TTC in in a young woman with multiple sclerosis

2015 ◽  
Vol 18 (09) ◽  
pp. 258-260
2016 ◽  
Vol 22 (6) ◽  
pp. 842-846 ◽  
Author(s):  
Luciana Midaglia ◽  
Jesús M Juega Mariño ◽  
Jaume Sastre-Garriga ◽  
Alex Rovira ◽  
Angela Vidal-Jordana ◽  
...  

Background: Clinically isolated syndromes affecting the brainstem may present with rare manifestations such as neurogenic pulmonary oedema (NPO). Objectives: We present the case of a 23 year-old man with NPO caused by Tako-Tsubo cardiomyopathy (TTC) as a first manifestation of multiple sclerosis (MS). Methods and Results: A brain magnetic resonance imaging scan at admission showed multiple supra and infratentorial white matter inflammatory demyelinating lesions. This examination was repeated 2 and 4 weeks after symptoms onset and active lesions showing contrast uptake were identified, two of them involving the pons and the medulla oblongata, probably affecting the solitary tract nucleus. Cerebrospinal fluid oligoclonal bands were detected. The patient was treated with a 3-day course of 1g intravenous methylprednisolone presenting a significant and progressive improvement. The proposed underlying physiopathology is an excessive secretion of catecholamines resulting in myocardial stunning and ventricular failure. Two months later he developed optic neuritis and disease-modifying treatment was initiated. Conclusions: Clinicians should consider a possible neurological origin of TTC, and according to the clinical characteristics of the patient, MS may be suspected.


2011 ◽  
Vol 17 (12) ◽  
pp. 1520-1522 ◽  
Author(s):  
C Papeix ◽  
R Depaz ◽  
A Tourbah ◽  
B Stankoff ◽  
C Lubetzki

We report the case of a young woman with multiple sclerosis who discontinued natalizumab twice and experienced a severe relapse following each natalizumab withdrawal. The first relapse was successfully treated by intravenous methylprednisolone (IVMP). In contrast the second relapse was unresponsive to IVMP. Subsequent treatment by plasma exchanges (PLEX) was followed by a dramatic neurological worsening. This case suggests that PLEX after natalizumab discontinuation may increase relapse severity.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Fatemeh Yavari ◽  
Sara Raji ◽  
Fatemeh Moradi ◽  
Morteza Saeidi

COVID-19, as a global concern and pivotal issue in the healthcare system, could have various presentations, leading to difficulty in diagnosis and management. Neuroinvasive potency, as claimed by preliminary studies, is a considerable pathogenesis. Serious neurological disorders like multiple sclerosis (MS) were out of the blue to be the first demonstration of COVID-19. This report highlights the representation of MS in a young woman, which resulted in a COVID-19 diagnosis.


2020 ◽  
Vol 45 ◽  
pp. 102427 ◽  
Author(s):  
Kate Kerpen ◽  
Ayanna Baptiste ◽  
Anusha K. Yeshokumar

1997 ◽  
Vol 11 (4) ◽  
pp. 367-370 ◽  
Author(s):  
Andrew Szilagyi ◽  
Hyman M Schipper ◽  
Norman Just

The case of a young woman who presented with nausea, vomiting and diarrhea is outlined; the etiology turned out to be a first attack of multiple sclerosis. Plausible mechanisms are discussed.


2021 ◽  
Vol 14 (7) ◽  
pp. e240581
Author(s):  
Jeny Jacob ◽  
Rajesh Venkataram ◽  
Giridhar Belur Hosmane

Scarce data exist about the coinfection of SARS‐CoV‐2 and Mycobacterium tuberculosis (MTB). A young woman who was undergoing treatment for multiple sclerosis was brought to our hospital with a COVID-19 positive status. On further evaluation, her chest X-ray showed right upper and mid-zone opacity, which lead to the suspicion of MTB. Her sputum came positive for acid-fast bacilli (AFB) staining and cartridge-based nucleic acid amplification test (CBNAAT) confirmed it, and rifampicin resistance was not detected. She was started on an antitubercular regimen. She was discharged, and by the end of the intensive phase of treatment, her symptoms subsided, but her sputum CBNAAT still showed the presence of TB bacillus.


2018 ◽  
Vol 4 (15) ◽  
pp. 184-189
Author(s):  
Mohsen Janghorbani ◽  
Mahdi Barzegar ◽  
Omid Mirmosayyeb ◽  
Vahid Shaygannejad ◽  
◽  
...  

2019 ◽  
pp. 01-04
Author(s):  
Thoams Mathew ◽  
Rohit Marol ◽  
Manjusha T ◽  
Anita Angela Baptist ◽  
Gareth J Parry

Red Ear Syndrome (RES) is a rare condition, first described in 1994 by Lance. It is characterized by burning pain, warmth, and erythema of the auricle. Here, we report the case of a young woman who manifested symptoms of red ear syndrome 3 years prior to those of multiple sclerosis (MS). She also had a history of episodic infrequent migraine and anxiety disorder. Association of Multiple Sclerosis (MS) with Red Ear Syndrome is hitherto unreported. We propose the involvement of Neuropeptide Y (NPY), or a dysfunction thereof, as the underlying pathophysiological mechanism to explain the concurrence of MS and RES, along with other presenting co-morbidities.


2016 ◽  
Vol 22 (6) ◽  
pp. 847-848 ◽  
Author(s):  
Max J Hilz

Autonomic dysfunction is common but frequently overlooked in multiple sclerosis (MS) patients. The case of a Tako-Tsubo cardiomyopathy on which this commentary is based shows that centrally triggered autonomic dysfunction may be the first life-threatening manifestation of MS.


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