scholarly journals New Approaches to the Surgical Treatment of Lung and Bronchial Tumors in Children

2021 ◽  
Vol 15 ◽  
pp. 311-317
Author(s):  
Oleg V. Bilokon ◽  
Elen V. Shaida ◽  
Petro P. Sokur ◽  
Borys O. Kravchuk
Keyword(s):  
Surgical Treatment ◽  
Malignant Tumors ◽  
Lung Metastases ◽  
Case Reports ◽  
Lung Tumors ◽  
Primary Tumors ◽  
Surgical Interventions ◽  
Pulmonary Lesions ◽  
Tissue Welding ◽  
Metastatic Lung

Today, it is relevant to search for new, better methods of surgical treatment of tumors and organ-preserving and video-assisted surgery is gaining more and more popularity. The aim of the study was to improve the results of surgical treatment of children with primary and secondary (metastatic) lung tumors using high-frequency live tissue welding (HF LTW) in order to increase the treatment effectiveness. Novelty of the study lies in the expanding the knowledge of the new researched method, for enhancement of survivability relatively to chemotherapy and radiation methods, that are studied in the previous works. Advantages of the introduced method are bloodless, fast, low traumatic operations 103 case reports in children with primary and metastatic lung tumors were analyzed, including 34 patients with benign and malignant lung tumors and 69 children with metastatic bronchial and pulmonary lesions undergoing treatment from 2002 to 2018 were examined. Benign lung tumors were diagnosed in 17 patients. Malignant tumors were observed in 17 patients, including 11 lung carcinoid tumors. Metastatic bronchial and pulmonary lesions most often occurred with osteosarcoma (28) and nephroblastoma (17). In 34 children with primary tumors, 37 were undergone surgical interventions. Most often, atypical resection was used – 16 (43.3%), in particular, with carcinoid – in 7 (43.8%) patients and with hamartoma – in 4 (25%) patients. In metastatic lesions, in most cases, the same resection was performed. From 58 resections 25 (43%) were performed for osteosarcoma and 15 (26%) for nephroblastoma. The HF LTW method was used in 29 patients for benign and malignant primary tumors and in 62 (73%) surgical procedures for lung metastases to remove a tumor, vascular coagulation and sealing of the lung tissue. Using HF LTW surgical operations of different directions and volumes can be performed effectively in benign, malignant and metastatic bronchial and pulmonary lesions in children.

scholarly journals Diagnostic Value of Bronchoscopy for Peripheral Metastatic Lung Tumors

Cancers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 375
Author(s):  
Yoshie Tsujimoto ◽  
Yuji Matsumoto ◽  
Midori Tanaka ◽  
Tatsuya Imabayashi ◽  
Keigo Uchimura ◽  
...  
Keyword(s):  
Malignant Tumors ◽  
Lung Metastases ◽  
Diagnostic Yield ◽  
Multivariable Analysis ◽  
Diagnostic Value ◽  
Lung Tumors ◽  
Lung Abscess ◽  
Endobronchial Ultrasound ◽  
Significant Difference ◽  
Metastatic Lung

Although lungs are one of the most frequent sites of metastasis for malignant tumors, little has been reported about the value of bronchoscopy for lung metastases presenting with peripheral pulmonary lesions (PPLs). This retrospective cohort study investigated the diagnostic value of bronchoscopy for peripheral metastatic lung tumors. Consecutive patients who underwent diagnostic bronchoscopy with radial endobronchial ultrasound for PPLs and were finally diagnosed with metastatic lung tumors from April 2012 to March 2019 were included. We analyzed 235 PPLs, with a median size of 18.8 mm. The overall diagnostic yield was 76.6%. In a multivariable analysis, large lesion size (>20.0 mm vs. <20.0 mm: 87.6% vs. 67.7%, p = 0.043, OR = 2.26), inner location (inner 2/3 vs. outer 1/3: 84.8% vs. 69.1%, p = 0.004, OR = 2.79), and visibility on radiography (visible vs. invisible: 83.2% vs. 56.1%, p = 0.015, OR = 3.29) significantly affected the diagnostic yield. Although a positive bronchus sign tended to have a higher yield, no significant difference was observed (81.8% vs. 70.6%, p = 0.063). Only one case of lung abscess was observed, with no serious complications. In conclusion, bronchoscopy is a valuable technique for peripheral metastatic lung tumors, with good diagnostic accuracy and safety.

Primary and Metastatic Lung Tumors in the Pediatric Population: A Review and 25-Year Experience at a Large Children's Hospital

2008 ◽  
Vol 132 (7) ◽  
pp. 1079-1103 ◽  
Author(s):  
Megan K. Dishop ◽  
Supriya Kuruvilla
Keyword(s):  
Medical Literature ◽  
Pediatric Population ◽  
Case Series ◽  
Lung Tumors ◽  
Malignant Neoplasms ◽  
Primary Tumors ◽  
Children's Hospital ◽  
Pathologic Features ◽  
Metastatic Lung ◽  
Children’S Hospital

Abstract Context.—Primary lung neoplasms are rare in children, but they comprise a broad and interesting spectrum of lesions, some of which are familiar from other tissue sites, and some of which are unique to the pediatric lung. Objective.—To determine the relative incidence of primary and metastatic lung tumors in children and adolescents through a single-institution case series, to compare these data to reports in the medical literature, to discuss the clinical and pathologic features of primary tumors of the tracheobronchial tree and lung parenchyma in children, and to provide recommendations for handling pediatric lung cysts and tumors. Data Sources.—A 25-year single institutional experience with pediatric lung tumors, based on surgical biopsies and resections at Texas Children's Hospital from June 1982 to May 2007, an additional 40 lung tumors referred in consultation, and a review of the medical literature. Conclusions.—A total of 204 pediatric lung tumors were diagnosed at our institution, including 20 primary benign lesions (9.8%), 14 primary malignant lesions (6.9%), and 170 secondary lung lesions (83.3%). The ratio of primary benign to primary malignant to secondary malignant neoplasms is 1.4:1:11.6. The common types of lung cancer in adults are exceptional occurrences in the pediatric population. The most common primary lung malignancies in children are pleuropulmonary blastoma and carcinoid tumor. Other primary pediatric lung tumors include congenital peribronchial myofibroblastic tumor and other myofibroblastic lesions, sarcomas, carcinoma, and mesothelioma. Children with primary or acquired immunodeficiency are at risk for Epstein-Barr virus–related smooth muscle tumors, lymphoma, and lymphoproliferative disorders. Metastatic lung tumors are relatively common in children and also comprise a spectrum of neoplasia distinct from the adult population.

scholarly journals Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review

2017 ◽  
Vol 22 (01) ◽  
pp. 094-102 ◽  
Author(s):  
Austin Nguyen ◽  
Adam Vaudreuil ◽  
Paul Haun ◽  
Gabriel Caponetti ◽  
Christopher Huerter
Keyword(s):  
Surgical Treatment ◽  
Clinical Presentation ◽  
Malignant Tumors ◽  
Case Reports ◽  
Data Synthesis ◽  
Excellent Outcome ◽  
Fibrous Histiocytomas ◽  
Pleomorphic Sarcoma ◽  
Level Data

Introduction Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is exceedingly rare in the tongue and not fully understood. Objectives This study systematically reviews the available literature discussing the clinical and pathological features of malignant and benign fibrous histiocytomas. Data Synthesis A total of 20 cases were included in this review. Patient-level data were extracted from cases to include clinical presentation, workup, treatment, and outcome. Conclusion Benign fibrous histiocytomas are consistent in clinical and histopathologic presentation. Surgical treatment provides excellent outcome, with no recurrence in all excised cases. Malignant tumors have a more aggressive clinical and pathological presentation. Surgical treatment with possible adjuvant radiotherapy resulted in recurrence in 40% of cases (follow-up of 24 months), and death due to disease in 47% of patients (follow-up of 19 months).

Surgical treatment of metastatic lung tumors — Recent changes in techniques and indications

Surgery Today ◽  
1997 ◽  
Vol 27 (12) ◽  
pp. 1123-1130 ◽  
Author(s):  
Ken Kodama ◽  
Osamu Doi ◽  
Masahiko Higashiyama ◽  
Hideoki Yokouchi ◽  
Keiko Kuriyama
Keyword(s):  
Surgical Treatment ◽  
Lung Tumors ◽  
Metastatic Lung

Surgical treatment for metastatic lung tumors with incidentally coexisting lung cancer

1999 ◽  
Vol 47 (4) ◽  
pp. 185-189 ◽  
Author(s):  
Masahiko Higashiyama ◽  
Ken Kodama ◽  
Hideoki Yokouchi ◽  
Koji Takami ◽  
Masao Kameyama ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Surgical Treatment ◽  
Lung Tumors ◽  
Metastatic Lung

scholarly journals Multilevel radical resection in treatment of patients with spine tumors

2021 ◽  
Vol 13 (2) ◽  
pp. 11-17
Author(s):  
R. M. Kabardaev ◽  
E. R. Musaev ◽  
A. K. Valiev ◽  
K. A. Borzov ◽  
S. F. Kuznetsov ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Malignant Tumors ◽  
Disease Free Survival ◽  
Functional Results ◽  
Radical Resection ◽  
Spinal Tumors ◽  
Benign Tumors ◽  
Study Objective ◽  
Surgical Interventions ◽  
National Medical

Introduction. Radical surgical resections in the treatment of malignant tumors of the spine have proven effective in improving both overall and disease-free survival of patients. Indications for such interventions are primary malignant tumors of the spine, primary benign tumors with aggressive growth, and solitary metastatic lesions in patients with a favorable oncological prognosis. Due to the anatomical features of the vertebral column, it is very difficult to perform radical resections. An even more difficult task is to perform such interventions for multilevel spinal lesions.The study objective is to evaluate the results of radical surgical treatment for multilevel tumor lesions of the spine.Materials and methods. From 2004 to 2019, in the department of spine surgery of the N.N. Blokhin National Medical Research Center of Oncology treated 36 patients with spinal tumors, who underwent multilevel radical resections. The analysis of this surgical treatment of patients with multilevel neoplastic lesions of the spine was carried out.Results. Performing radical surgical interventions on the spine makes it possible to reduce the frequency of local relapses, improve functional results and overall survival of patients. After performing multilevel resections, complications often occur.

scholarly journals P2.16-026 Surgical Treatment for Metastatic Lung Tumors from Various Sarcomas

2017 ◽  
Vol 12 (11) ◽  
pp. S2198
Author(s):  
H. Yamamoto ◽  
K. Namba ◽  
K. Takahashi ◽  
J. Soh ◽  
K. Shien ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Lung Tumors ◽  
Metastatic Lung

scholarly journals Video-Assisted Thoracoscopic Surgery in Patients With Clinically Resectable Lung Tumors

1996 ◽  
Vol 2 (3) ◽  
pp. 151-155
Author(s):  
H. Sakai ◽  
P. J. Borgstein ◽  
M. A. Cuesta ◽  
S. Meijer ◽  
J. C. van Mourik ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Malignant Tumors ◽  
Lung Metastases ◽  
Thoracoscopic Surgery ◽  
Lung Tumors ◽  
Benign Tumors ◽  
Metastatic Tumors ◽  
Thoracoscopic Resection ◽  
Lung Cancers ◽  
Video Assisted

To investigate the feasibility of thoracoscopic resection, a pilot study was performed in patients with clinically resectable lung tumors. In 40 patients, Video-assisted thoracic surgery (VATS) was performed because of suspicion of malignancy. There were 29 men and 11 women with a median age of 54.8 years (range 18 to 78). Preoperative indications were suspected lung cancer and tumor in 27 patients, assessment of tumor resectability in 7 patients, and probability of metastatic tumors in 6 patients. The final diagnoses in the 27 patients with suspected lung cancer were 12 primary lung cancers, 6 lung metastases, and 9 benign lesions. The success rates for VATS (no conversion to thoracotomy) were 1 of 12 (8.3%) for resectable stage I lung cancer, 8 of 12 (66.7%) for metastatic tumors, and 9 of 9 (100%) for benign tumors. With VATS, 6 of 7 patients (85.7%), possible stage III non-small cell lung cancer, an explorative thoracotomy with was avoided, significantly reducing morbidity. The reasons for conversion to thoracotomy were 1) oncological (N2 lymph node dissection and prevention of tumor spillage) and 2) technical (inability to locate the nodule, central localization, no anatomical fissure, or poor lung function requiring full lung ventilation). The ultimate diagnoses were 19 lung cancers, 12 metastatic lung tumors, and 9 benign lung tumors. Our data show the limitations of VATS for malignant tumors in general use. These findings, together with the fact that experience in performing thoracoscopic procedures demonstrates a learning curve, may limit the use of thoracoscopic resection as a routine surgical procedure, especially when strict oncological rules are respected.

scholarly journals MA20.11 Surgical Treatment for Metastatic Lung Tumors from Sarcomas of Soft Tissue and Bone

2019 ◽  
Vol 14 (10) ◽  
pp. S334
Author(s):  
H. Yamamoto ◽  
K. Namba ◽  
H. Yamamoto ◽  
T. Toji ◽  
J. Soh ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Soft Tissue ◽  
Lung Tumors ◽  
Metastatic Lung

scholarly journals How Do Synchronous Lung Metastases Influence the Surgical Management of Children with Hepatoblastoma? An Update and Systematic Review of the Literature

Cancers ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1693 ◽  
Author(s):  
Roberta Angelico ◽  
Chiara Grimaldi ◽  
Carlo Gazia ◽  
Maria Cristina Saffioti ◽  
Tommaso Maria Manzia ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Metastatic Disease ◽  
Negative Impact ◽  
Lung Metastases ◽  
Current Management ◽  
Liver Tumours ◽  
Primary Liver Tumor ◽  
Metastatic Lung ◽  
Primary Liver Tumours ◽  
Unresectable Metastases

Approximately 20% of children with hepatoblastoma (HB) have metastatic disease at diagnosis, most frequently in the lungs. In children with HB, lung metastatic disease is associated with poorer prognosis. Its treatment has been approached with a variety of methods that integrate chemotherapy and surgical resection. The timing and feasibility of complete extirpation of lung metastases, by chemotherapy and/or metastasectomy, is crucial for the surgical treatment of the primary liver tumor, which can vary from major hepatic resections to liver transplantation (LT). In children with unresectable HB, which can be surgically treated only by LT, the persistence of unresectable metastases after neoadjuvant chemotherapy excludes the possibility of recurring to LT with consequent negative impact on patients’ outcomes. Due to limited evidence and experience, there is no consensus amongst oncologists and surgeons across institutions regarding the surgical treatment for HB with synchronous metastatic lung disease. This narrative review aimed to update the current management of pulmonary metastasis in children with HB and to define its role in the decision-making strategy for the surgical approach to primary liver tumours.

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