scholarly journals AN OPEN-LABEL CLINICAL TRIAL TO PROVE THE EFFICACY OF HIRUDOTHERAPY IN REDUCING THE INCREASED INTRA-OCULAR PRESSURE IN GLAUCOMA

2021 ◽  
Vol 9 (7) ◽  
pp. 1358-1361
Author(s):  
Jeena N.J.
Keyword(s):  
Intraocular Pressure ◽  
Conventional Treatment ◽  
Treatment Method ◽  
Open Label ◽  
Intra Ocular Pressure ◽  
Leech Therapy ◽  
Disease Condition ◽  
Before And After ◽  
Ocular Pressure ◽  
Cardinal Feature

Glaucoma is a chronic disease condition prevalent globally leading to blindness. It results in optic neuropathy which is very difficult to manage. An increase in intraocular pressure is a cardinal feature in most cases. This study aims at lowering the intraocular pressure by leech therapy, which is a conventional treatment method described in Ayur- veda. Leech therapy was conducted in the selected patients and intraocular pressure before and after treatment were recorded. The study showed clinically and statistically significant changes in the intraocular pressure. Keywords: Leech therapy, glaucoma, intraocular pressure

Early Post-Operative Effect of Phacoemulsification on Anterior Chamber Depth and Intraocular Pressure in Patients with Cataract

2021 ◽  
Vol 37 (2) ◽  
Author(s):  
Mashal Tayyab ◽  
Awaid Abid
Keyword(s):  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Anterior Chamber Depth ◽  
Pressure Change ◽  
P Value ◽  
Iol Implantation ◽  
Intra Ocular Pressure ◽  
Significant Difference ◽  
Ocular Pressure ◽  
The Mean

Purpose:  To determine the Anterior Chamber depth and Intraocular pressure change following uncomplicated phacoemulsification. Study Design:  Quasi experimental study. Place and Duration of Study:  Layyton Rehmatullah Benevolent Trust Free Eye and Cancer Hospital, Lahore from 16/12/2017 to 15/06/2018. Methods:  One hundred and thirty nine patients who came to Layyton Rehmatullah Benevolent Trust Free Eye for phacoemulsification and IOL implantation were included in the study. Anterior Chamber depth was measured with IOL Master and intraocular pressure was determined using Goldmann Applanation Tonometer one day before and one month after surgery. Data was recorded on a self-designed proforma. Comparison between pre- and post-operative data with respect to change was analyzed by chi-square test. P-value ≤ 0.05 was considered significant. Results:  The mean intra-ocular pressure dropped from 14.36 ± 4.19 mmHg to 12.14 ± 4.26 mmHg 1 month after surgery with a mean drop of 2.21 ± 0.65 mmHg while the mean anterior chamber depth increased from 2.31 ± 0.08 mm to 3.59 ± 0.37 mm with a mean increase of 1.29 ± 0.36 mm. There was no statistically significant difference in the mean change of intra-ocular pressure and anterior chamber depth across various subgroups based on patient’s age, gender and duration of cataract. Conclusion:  Phacoemulsification and IOL implantation not only improves the visual acuity by removing the cataract but also deepens the anterior chamber and decreases intra-ocular pressure, which can have a beneficial effect in glaucoma patients. Key Words:  Phacoemulsification, Cataract, Intraocular pressure, Lens, Anterior chamber depth.

Comparison of intraocular pressure fluctuation before and after cataract surgeries in normal-tension glaucoma patients

2018 ◽  
Vol 29 (5) ◽  
pp. 516-523 ◽  
Author(s):  
Naoki Tojo ◽  
Mitsuya Otsuka ◽  
Atsushi Hayashi
Keyword(s):  
Regression Analysis ◽  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Contact Lens ◽  
Pressure Fluctuations ◽  
Normal Tension Glaucoma ◽  
Open Label ◽  
Before And After ◽  
Contact Lens Sensor ◽  
Harmonic Regression

Purpose: Cataract surgeries have been shown to reduce intraocular pressure. We used a Sensimed Triggerfish® contact lens sensor to compare intraocular pressure levels and their fluctuation between before and after cataract surgeries in patients with normal-tension glaucoma. Methods: This was a prospective open-label study. Thirteen patients with normal-tension glaucoma were included. All patients underwent a 1-month washout and discontinued glaucoma medications during this study. In each eye, intraocular pressure fluctuations over 24 h were measured with the contact lens sensor before and at 3 months after the cataract surgery. We compared intraocular pressure levels and their fluctuation between before and after cataract surgeries. We used two approaches to evaluate the amplitude of intraocular pressure fluctuations: dual-harmonic regression analysis, and measurement of the difference between the maximum and the minimum value. Results: The mean pre-operative intraocular pressure was 14.7 ± 2.2 mm Hg and mean post-operative intraocular pressure was 11.4 ± 2.2 mm Hg. Cataract surgery significantly decreased intraocular pressure (p = 0.0005). In both methods, the post-operative fluctuations in intraocular pressure over 24 h were significantly smaller than their pre-operative counterparts (dual-harmonic regression analysis: p = 0.0171; difference between the maximum and the minimum: p = 0.0398). Conclusion: Cataract surgery decreased both intraocular pressure values and intraocular pressure fluctuations in normal-tension glaucoma patients.

Effect of General Anesthesia on Intra-ocular Pressure during Ophthalmic Procedures in Our Population

2021 ◽  
Vol 15 (10) ◽  
pp. 2614-2615
Author(s):  
Tariq Pervaiz Khan ◽  
Fakhar Humayun ◽  
Qumber Abbas ◽  
Abaid Ur Rehman ◽  
Faiza Hameed ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
General Anesthesia ◽  
Posterior Segment ◽  
Ocular Motility ◽  
Inhalation Anesthetics ◽  
Intra Ocular Pressure ◽  
Anesthetic Agents ◽  
Department Of Ophthalmology ◽  
Ocular Pressure ◽  
The Mean

Aim: To determine changes in intraocular pressures (IOP) associated with drugs used for general anesthesia (GA) induction in eye surgery. Study design: Observational prospective study Place and duration of study: Department of Ophthalmology, CMH Rawalpindi from 1st March 2015 to 31st May 2016. Methodology: Eighty subjects that were advised to undergone various ophthalmic surgical procedures under GA were included in the study. Visual acuity, intraocular pressure (IOP), extra ocular motility, anterior and dilated posterior segment examination were carried out to determine the ophthalmic status. Mixed anesthetics were used in all patients. IOP was recorded at T1 (10 min before induction of anesthesia), T2 (10 min after intubation), and T3 (at the conclusion of surgery before extudation) using Perkins tonometers. Changes in IOP before induction of GA, after intubation, and just before extubation were recorded. Results: Mean pre-anesthesia IOP for patients of age was 42.3 years with a range of 9-70 years and mean IOP was 16.4 with a range of 10-23 mmHg. There was a significant decrease in the mean IOP at T2 (Perkins: 4-6 mmHg) and T3 (Perkins: 5-8mmHg) as compared to the IOP at T1 (10-18mmHg. The decreases in IOPs at T2 and T3 were similar in both anesthetic groups (T2: P=4-6mmHg; T3: P = 5-8 mmHg). Conclusion: Significant decrease in IOP after GA was observed with mixed anesthetic agents. For management decisions this aspect of general anaesthesia drugs on IOP as noted with currently used anesthetic agents has to be accounted for and decisions are taken accordingly. Keywords: General anesthesia, inhalation anesthetics, intraocular pressure, Perkins tonometers

scholarly journals Non-contact Tonometry Versus Pachymetry Corrected Intraocular Pressure: Any Difference? A Case for Pachymetry during Glaucoma Screening

2019 ◽  
pp. 1-7
Author(s):  
E. Awoyesuku ◽  
A. A. Onua
Keyword(s):  
Intraocular Pressure ◽  
Pressure Measurement ◽  
Corneal Thickness ◽  
Intra Ocular Pressure ◽  
Glaucoma Screening ◽  
Port Harcourt ◽  
Department Of Ophthalmology ◽  
Significant Difference ◽  
Ocular Pressure ◽  
The Mean

Objective: This study sets out to determine if there is any statistical difference in the results of measuring intraocular pressure (IOP) uncorrected for Central Corneal Thickness with Air Puff Tonometry and corrected with pachymetry for clients undergoing screening for glaucoma at the department of Ophthalmology, University of Port Harcourt Teaching Hospital (UPTH), Nigeria. Methods: One hundred and thirty-two (132) adults were screened for glaucoma during the 2019 World Glaucoma week in UPTH Port Harcourt, they had their IOPs measured with Air Puff (Non-contact) Tonometer (Pulsair intelliPuff Tonometer, Keeler), after which they underwent pachymetry (Sonomed Escalon PacScan Plus) to determine corneal thickness after which the corrected IOP was determined by using a correction factor for adjusting IOP based on corneal thickness [1].  The results were analyzed using SPSS version 20 to determine statistical differences. Results: There was a statistically significant difference between intraocular pressure (IOP) measurements when corrected with pachymetry than when it is uncorrected. In our study the mean uncorrected IOP RE and LE was 14.53 mmHg and14.75 mmHg respectively while Corrected IOP RE and LE was 16.37 mmHg and 16.72 mmHg respectively. Conclusion: Intra ocular pressure measurement adjusted with pachymetry for corneal thickness may be a better option for tonometry and we propose this be considered during intra ocular pressure measurement.

scholarly journals INTRA OCULAR PRESSURE

2018 ◽  
Vol 25 (12) ◽  
pp. 1833-1839
Author(s):  
Arsalan Ahmed Rajput ◽  
Azfar Ahmed Mirza ◽  
Ghazi Khan Maree ◽  
Adil Ali Shaikh
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
P Value ◽  
Strong Positive Correlation ◽  
Positive Correlation ◽  
Intra Ocular Pressure ◽  
Department Of Ophthalmology ◽  
Ocular Pressure ◽  
The Mean

Introduction: The ideal optical properties of the eye requires support of state of the eye-ball which is normally regulated by the intraocular pressure (IOP). There is variation in the measurements of IOP with Goldmann applanation tonometry if the thickness of the central cornea is not uniform, the IOP is high when cornea is thicker and vice versa. Therefore, the central corneal thickness (CCT) is thought to affect the IOP readings, however, as shown, the evidence available remains controversial. The aim of the study was to determine correlation between CCT and IOP. Objectives: To determine the correlation between the Central Corneal Thickness (CCT) and Intra Ocular Pressure (IOP). Study Design: A cross-sectional study. Placeand Duration: Department of Ophthalmology, Aga Khan University Hospital, Karachi from July to December, 2014. Methodology: During the study period of six months total 431 participants were purposively sampled according to the set criteria. Variables included were age, gender, CCT, and IOP. Correlation between IOP and CCT was assessed by using Pearson correlation test, P value of < 0.05 was considered significant. Results: Out of 431 participants, 239 (55.5%) males and 192 (44.5%) females. The mean age was 34.9 ranging from 20 to 50 years. The mean central corneal thickness of right eye was 529 μm with SD ± 39.5 and range of 473-591 μm. The mean intraocular pressure of right eye was 14.7 μm, SD ± 3.1 with a range of 9-21 mmHg. The left eye mean central corneal thickness was 533, SD ± 29.6 with range of 481-589 μm. The mean intraocular pressure of left eye was 15.6, SD ± 3.1 with a range of 10-21 mmHg. Strong positive correlation was found (P-value < 0.001) between central corneal thickness andintra ocular pressure for both eyes. Conclusion: There is positive correlation between CCT and IOP. Therefore, along with the routine ophthalmic examination for intraocular pressure measurements pachymetry should also be considered for accurate interpretation of the results.

scholarly journals Mean Change in Intra-Ocular Pressure in patients undergoing Trabeculectomy with Mitomycin C

2021 ◽  
Vol 15 (5) ◽  
pp. 1044-1046
Author(s):  
Munib Ur Rehman ◽  
Shahid Mahmood Dayal ◽  
Ali Zain Ul Abidin
Keyword(s):  
Intraocular Pressure ◽  
Mitomycin C ◽  
Congenital Glaucoma ◽  
P Value ◽  
Cross Sectional ◽  
Primary Congenital Glaucoma ◽  
Intra Ocular Pressure ◽  
Department Of Ophthalmology ◽  
Significant Difference ◽  
Ocular Pressure

Aim: To examine the outcomes of trabeculectomy followed by mitomycin C in term of mean change in intra-ocular pressure in patients presented with primary congenital glaucoma. Study design: Cross-sectional/observational Place and duration of study: Department of Ophthalmology, Khawaja Muhammad Safdar Medical College, Allama Iqbal Memorial Teaching Hospital, Sialkot from 7th July 2020 to 6thJanuary 2021. Methods: Fortypatients of both genders with ages up to 5 years presented with primary congenital glaucoma were enrolled in this study. Patients demographics were recorded after taking written consent from parents/guardians. All the patients were receivedtrabeculectomy with 0.4mg/ml Mitomycin C was applied below the flap for 2 to 3 minutes. Intraocular pressure was examined preoperatively and at 12th day after surgery. Results:Twenty-four (60%) were males while 16 (40%) were females. 30 (75%) patients were ages <2yearsand 10 (25%) patients had ages >2 years. A significant difference was observed regarding mean change in intra-ocular pressure (pre-operatively 30.48±3.62 versus post-operatively 16.35±2.86) with p-value <0.001. Conclusion: Trabeculectomy with Mitomycin C is very effective for reducing intraocular pressure. A significant decrease in intra-ocular pressure was observed post-operatively. Keywords: Primary congenital glaucoma, Intra-ocular pressure, Trabeculectomy, Mitomycin C

Chronic Paroxysmal Hemicrania: X. On the Autonomic Involvement

Cephalalgia ◽  
1986 ◽  
Vol 6 (2) ◽  
pp. 113-124 ◽  
Author(s):  
Ottar Sjaastad ◽  
Jan Aasly ◽  
Torbjørn Fredriksen ◽  
Maria M Wysocka Bakowska
Keyword(s):  
Topical Administration ◽  
Blocking Agent ◽  
Nasal Secretion ◽  
Head Movements ◽  
Pressure Increase ◽  
Paroxysmal Hemicrania ◽  
Intra Ocular Pressure ◽  
Before And After ◽  
Chronic Paroxysmal Hemicrania ◽  
Ocular Pressure

In four patients with chronic paroxysmal hemicrania, two of whom could precipitate attacks mechanically, various autonomic function tests were carried out in connection with attacks. Not all features could be studied in all patients, Forehead sweating and temperature were measured. Sweating, tearing, and nasal secretion were studied after systemic atropine administration, which reduced attack-related sweating, tearing, and nasal secretion markedly. Intra-ocular pressure was measured before and after the topical administration of an alpha-receptor blocking agent, thymoxamine. After topical thymoxamine no definite intra-ocular pressure increase occurred during precipitated attacks. In attacks precipitated by head movements, forehead sweating occurred seconds (up to 30 sec) before the pain. This study indicates that at least in some CPH cases, forehead sweating is not caused by the pain. Nor is the pain secondary to increase in intra-ocular pressure. The thymoxamine experiments seem to indicate that alpha-receptors in some way may be connected with the intra-ocular pressure increase during attack.

scholarly journals INTRAOCULAR PRESSURE

2016 ◽  
Vol 23 (03) ◽  
pp. 317-323
Author(s):  
Muhammad Shahid Faruqi Faruqi ◽  
Abdul Rehman Khokhar ◽  
Abdul Ghaffar Khan ◽  
Tanvir Ali Shirwany
Keyword(s):  
Intraocular Pressure ◽  
P Value ◽  
Intra Ocular Pressure ◽  
Applanation Tonometer ◽  
Healthy Control ◽  
Ocular Pressure ◽  
Study Methodology ◽  
Student’S T ◽  
Age And Sex ◽  
Student’S T Test

Objectives: To evaluate the intraocular pressure in diabeto-hypertensivesubjects and age and sex matched normal healthy adults. Study Design: Cross-sectionalanalytic study. Methodology: 50 subjects visiting the out-patient department (OPD) ofOphthalmology in Lahore General Hospital, Lahore, were examined. 25 were newly diagnoseddiabeto-hypertensive, and 25 normal healthy were selected from the relatives of these patients.IOP was checked by Goldman Applanation Tonometer. Blood pressure was checked bymercury sphygmomanometer. Blood glucose level checked by glucometer. Results: The IOPwas raised in both eyes of diabeto-hypertensive patients and there was a significant differencein intraocular pressure of normal healthy control and diabeto-hypertensive subjects. Thedifferences between two groups was analyzed by paired Student’s t-test. The P-value was<0.001. Conclusion: Intra-ocular pressure can be raised in all diabeto-hypertensive subjects,which shows that co-existence of diabetes and hypertension were important risk factor forraised intraocular pressure.

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