scholarly journals COMPARATIVE CLINICAL EFFICACY OF ARK TAILA AND ARK CREAM APPLICATION IN THE MANAGEMENT OF VICHARCHIKA - AN OPEN LABELLED, RANDOMISED CONTROLLED CLINICAL TRIAL

2020 ◽  
Vol 8 (7) ◽  
pp. 3843-3849
Author(s):  
Suman Purohit ◽  
Saurabh 2 ◽  
Yadevendra Yadav
Keyword(s):  
Symptomatic Relief ◽  
Topical Therapy ◽  
Skin Irritation ◽  
Signs And Symptoms ◽  
Controlled Clinical Trial ◽  
Randomised Controlled Clinical Trial ◽  
Group A ◽  
Group B ◽  
Randomised Controlled

Vicharchika is one of Kushtha included under Rakta Pradoshaja Vikaras, recurrent and chronic in nature. Modern dermatologists use topical therapy such as topical corticosteroid; topical emollients etc. to give symptomatic relief but it cost in severe long-term toxicity, skin irritation and may cause skin cancer. In Ayurvedic texts, there are hundreds of medicaments as a successful and safer remedy for the chronic der-ma problems including Vicharchika. Acharya Sharangdhar had depicted one such formulation “Ark Taila” for treating Vicharchika. Sneha Siddha drugs have better pharmacokinetics action in comparison to other dosage form because of the lipid nature of bio- membrane, as lipid soluble substances readily perme-ate into cells. Aim and Objective: To compare the efficacy of Ark Taila and Ark cream application in the management of Vicharchika. Materials and Methods: In this study, 30 patients of Vicharchika were se-lected and randomly allocated into two groups. In group A, Ark Taila (n = 15), and in group B Ark cream (n = 15) was given to patients for local application. Patients were assessed for relief in signs and symptoms at interval for fifteen days for sixty days. Results: Patients of group A has maximum relief in sign and symp-toms of Vicharchika in comparison of group B. Conclusion: The study concluded that Ark Taila is an ef-fective formulation of choice for the management of Vicharchika as compared to Ark cream.

Comparison of the Effectiveness of Acupuncture Treatment and Local Anaesthetic Injection for Low Back Pain: A Randomised Controlled Clinical Trial

2009 ◽  
Vol 27 (4) ◽  
pp. 174-177 ◽  
Author(s):  
Motohiro Inoue ◽  
Tatsuya Hojo ◽  
Miwa Nakajima ◽  
Hiroshi Kitakoji ◽  
Megumi Itoi
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Local Anaesthetic ◽  
Controlled Clinical Trial ◽  
Low Back ◽  
Randomised Controlled Clinical Trial ◽  
Group A ◽  
Randomised Controlled ◽  
Anaesthetic Injection ◽  
Local Anaesthetic Injection

Objective To compare the effectiveness of repeated acupuncture stimulation and local anaesthetic injection at the most painful points in patients with low back pain. Method This randomised controlled clinical trial involved 26 patients with low back pain randomly allocated to either an acupuncture group (n = 13) or a local anaesthetic injection group (n = 13). Both acupuncture and anaesthetic injection were performed at two to five of the most painful points on the lower back once weekly for 4 weeks. In the acupuncture group, a 0.18 mm diameter stainless steel needle was inserted to a depth of 10–20 mm and manual stimulation was applied. In the local anaesthetic injection group, a 0.5 mm diameter needle was inserted to a depth of 10–20 mm and a local anaesthetic was injected. Participants evaluated pain using a Visual Analogue Scale immediately before and after the first treatment, before each subsequent treatment, and at 2 weeks and 4 weeks after completion of treatment. Results There was a significant difference between the two groups in the change in Visual Analogue Scale pain scores (p<0.01), with acupuncture providing more favourable results than local anaesthetic injection. The reduction in pain score from baseline calculated at each time period was significantly different between the two groups after the first (p<0.05) and final (p<0.01) treatments, and during the follow-up period (after 2 weeks (p<0.01) and 4 weeks (p<0.05)). Conclusion Both injection and acupuncture relieved pain, but acupuncture was superior for the immediate and sustained effects, suggesting that it is a useful treatment for low back pain. The difference in the effects may be attributable to differences in the mechanism of pain suppression.

scholarly journals A RANDOMISED CONTROLLED CLINICAL TRIAL TO STUDY THE EFFICACY OF SATYADI CHURNA AND VYAGHRI CHURNA IN TAMAKA SWASA

2021 ◽  
Vol 9 (9) ◽  
pp. 2006-2011
Author(s):  
Anagha Narayanan ◽  
Susheel Shetty
Keyword(s):  
Bronchial Asthma ◽  
Treatment Modalities ◽  
Rank Test ◽  
Controlled Clinical Trial ◽  
Group Comparison ◽  
Signed Rank ◽  
Signed Rank Test ◽  
Group A ◽  
Group B ◽  
Randomised Controlled

Background and Objectives: Tamaka Swasa is a form of Swasa Roga primarily affecting the Pranavaha Srotas characterized by Swasakrichratha, Ghurghuraka, Teevra vega Swasa etc. Tamaka Swasa in Ayurvedic classics appears to be similar to Bronchial Asthma. Several medications are available in today’s medical system to treat this disease, but they are known to cause a variety of side effects. Hence, the suffering population is turning to conventional remedies for better relief. In this regard, Ayurveda can provide promising results in Tamaka Swasa with varieties of treatment modalities. In light of these considerations, the aim of the study was to assess the efficacy of two Ayurvedic formulations Satyadi Churna listed in Swasakarmavipaka adhyaya in Brihat Nighantu Ratnakara and Vyaghri Churna mentioned in Curnakalpana Adhyaya in Sharangdhara Samhita in the treatment of mild to moderate Bronchial Asthma. Materials and Methods: 40 Tamaka Swasa Subjects were selected those fulfilling the diagnostic and inclusion criteria. They were randomly assigned into two equal groups. Comparative analysis of the overall effect of the treatments in both the Groups was done statistically with Mann- Whitney Rank Sum Test and within the Group comparison with Wilcoxon Signed Rank Test. Results: Within the group comparison showed statistically significant results for all the criteria in Group A while in Group B except Peenasa all other criteria showed statistically significant results. Conclusion: When comparing both groups Satyadi Churna showed better improvement in the symptoms of Tamaka Swasa than Vyaghri Churna. Hence H1 holds good and proved. Keywords: Tamaka Swasa, Bronchial Asthma, Satyadi Churna, Vyaghri Churna, Peak flow meter.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECTIVENESS OF VASADI DASHANGA KWATHA AND PATOLADI KWATHA IN AMLAPITTA (NON ULCER DYSPEPSIA)

2020 ◽  
pp. 29-37
Author(s):  
Mithun.K ◽  
K.Ravindra Bhat
Keyword(s):  
Clinical Study ◽  
Statistical Tests ◽  
Signs And Symptoms ◽  
Standard Dosage ◽  
Life Styles ◽  
Life Style Changes ◽  
Group A ◽  
Non Ulcer Dyspepsia ◽  
Group B

The ignorance about food and present life styles has made people at large to indulge in unwholesome food habits and regimens. Due to this lifestyle and improper diet pattern, there will be metabolic impairment leading to Amlata and Vidhagdhata of the consumed food. This is recognized as Amlapitta in Ayurveda. The Lakshanas of Amlapitta can be correlated with signs and symptoms of Non-ulcer Dyspepsia. The line of treatment as per allied science is life style changes, use of H2 receptor blocking agents and Proton Pump Inhibitors (PPI). Long term use of these antacids has shown various side effects. The patients with non ulcer Dyspepsia will have regurgitation despite of adequate acid suppression by treatment. It causes significant economic impact due to the long-term management of the disease and costs of possible complications. There is a need for a better medicine which can counter such changes and can reduce Amlata and Vidagdhata of consumed food. Medicines explained in Ayurveda have the ability to do the same. For this purpose, Vasadidashanga kwatha which is explained in Bhaishajya Ratnavali in comparison with Patoladikwatha as per mentioned in Chakradatta in the management of Amlapitta is been undertaken. Methods: In Clinical study, 60 patients fulfilling the diagnostic inclusion criteria were selected from OPD and IPD of Hospitals of South Canara and special camps conducted for the same. Patients were divided into 2 groups Group A and Group B and compared with Vasadidashangakwatha and Patoladikwatha with the standard dosage of Kwatha for a period of 30 days. Results: Assessment of the total effect of therapy was made by analyzing the data with suitable statistical tests of significance. Overall the test has shown significant result in Group A compared to Group B. Conclusion: Both Vasadidashanga kwatha and Patoladi kwatha showed good results in reduction of signs and symptoms of Amlapitta. Vasadidashanga kwatha gave better results in comparison with Patoladikwatha clinically. The statistical analysis also supported this by concluding that the improvement after treatment is highly significant in Group A (Vasadidashanga kwatha) when compared to Group B (Patoladikwatha).

scholarly journals Platelet-Rich Plasma versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis: A Prospective Randomized Controlled Clinical Trial

Cartilage ◽  
2018 ◽  
Vol 12 (1) ◽  
pp. 51-61 ◽  
Author(s):  
Michael-Alexander Malahias ◽  
Leonidas Roumeliotis ◽  
Vasileios S. Nikolaou ◽  
Efstathios Chronopoulos ◽  
Ioannis Sourlas ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Platelet Rich Plasma ◽  
Symptomatic Relief ◽  
Controlled Clinical Trial ◽  
Dash Score ◽  
Ultrasound Guided ◽  
Radiographic Osteoarthritis ◽  
Group A ◽  
Group B

Various systematic reviews have recently shown that intra-articular platelet-rich plasma (IA-PRP) can lead to symptomatic relief of knee osteoarthritis for up to 12 months. There exist limited data on its use in small joints, such as the trapeziometacarpal joint (TMJ) or carpometacarpal joint (CMCJ) of the thumb. A prospective, randomized, blind, controlled, clinical trial of 33 patients with clinical and radiographic osteoarthritis of the TMJ (grades: I-III according to the Eaton and Littler classification) was conducted. Group A patients (16 patients) received 2 ultrasound-guided IA-PRP injections, while group B patients (17 patients) received 2 ultrasound-guided intra-articular methylprednisolone and lidocaine injections at a 2-week interval. Patients were evaluated prior to and at 3 and 12 months after the second injection using the visual analogue scale (VAS) 100/100, shortened Disabilities of the Arm, Shoulder, and Hand Questionnaire (Q-DASH), and patient’s subjective satisfaction. No significant differences between the baseline clinical and demographic characteristics of the 2 groups were identified. After 12 months’ follow-up, the IA-PRP treatment has yielded significantly better results in comparison with the corticosteroids, in terms of VAS score ( P = 0.015), Q-DASH score ( P = 0.025), and patients’ satisfaction ( P = 0.002). Corticosteroids offer short-term relief of symptoms, but IA-PRP might achieve a lasting effect of up to 12 months in the treatment of early to moderate symptomatic TMJ arthritis.

scholarly journals Pelvic Organ Prolapse Repair with and without Concomitant Burch Colposuspension in Incontinent Women: A Randomised Controlled Trial with at Least 5-Year Followup

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Elisabetta Costantini ◽  
Massimo Lazzeri ◽  
Vittorio Bini ◽  
Michele Del Zingaro ◽  
Emanuela Frumenzio ◽  
...  
Keyword(s):  
Controlled Trial ◽  
Pelvic Organ ◽  
Stage I ◽  
Burch Colposuspension ◽  
Group A ◽  
Group B ◽  
Randomised Controlled ◽  
The Impact ◽  
Pop Repair

The aim of this study was to reevaluate and update the followup of a previously published randomized controlled trial (RCT) on the impact of Burch Colposuspension (BC), as an anti-incontinence procedure, in patients with UI and POP, who underwent POP repair. Forty-seven women were randomly assigned to abdominal POP repair and concomitant BC (24 patients; group A) or POP repair alone without any anti-incontinence procedure (23 patients; group B). Median followup was 82 months (range 60–107); from over 47 patients, 30 reached 6-year followup. Two patients were lost at followup. In group A, 2 patients showed a stage I rectocele. In group B, 2 patients had a stage I rectocele and 1 a stage II rectocele. In group A, 13/23 (56.5%) were still incontinent after surgery compared with 9/22 patients (40.9%) in group B (P=0.298). No significant changes were observed between the first and the current followup. The update of long-term followup confirmed that BC did not improve outcome significantly in incontinent women when they undergo POP repair.

Comparative Study of effectiveness of mobilization with movement (MWM) and End range mobilization (ERM) techniques in frozen shoulder

2018 ◽  
Vol 4 (4) ◽  
pp. 519-522
Author(s):  
Jeyakumar S ◽  
Jagatheesan Alagesan ◽  
T.S. Muthukumar
Keyword(s):  
Range Of Motion ◽  
Frozen Shoulder ◽  
Type I ◽  
Mean Values ◽  
Functional Activities ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Frozen shoulder is disorder of the connective tissue that limits the normal Range of motion of the shoulder in diabetes, frozen shoulder is thought to be caused by changes to the collagen in the shoulder joint as a result of long term Hypoglycemia. Mobilization is a therapeutic movement of the joint. The goal is to restore normal joint motion and rhythm. The use of mobilization with movement for peripheral joints was developed by mulligan. This technique combines a sustained application of manual technique “gliding” force to the joint with concurrent physiologic motion of joint, either actively or passively. This study aims to find out the effects of mobilization with movement and end range mobilization in frozen shoulder in Type I diabetics. Materials and Methods: 30 subjects both male and female, suffering with shoulder pain and clinically diagnosed with frozen shoulder was recruited for the study and divided into two groups with 15 patients each based on convenient sampling method. Group A patients received mobilization with movement and Group B patients received end range mobilization for three weeks. The outcome measurements were SPADI, Functional hand to back scale, abduction range of motion using goniometer and VAS. Results: The mean values of all parameters showed significant differences in group A as compared to group B in terms of decreased pain, increased abduction range and other outcome measures. Conclusion: Based on the results it has been concluded that treating the type 1 diabetic patient with frozen shoulder, mobilization with movement exercise shows better results than end range mobilization in reducing pain and increase functional activities and mobility in frozen shoulder.

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