scholarly journals A RARE PRESENTATION OF ATRIAL FIBRILLATION AND THROMBOTIC MICROANGIOPATHY, (THROMBOTIC THROMBOCYTOPENIC PURPURA - TTP) CAUSED BY ALCOHOL AND PRODUCTS OF CANNABIS (MARIJUANA)

2022 ◽  
Vol 54 (4) ◽  
pp. 373-376
Author(s):  
Samar Iltaf ◽  
Saira Awan ◽  
Saira Abbas ◽  
Salma Salman ◽  
Shariq Mirza
Keyword(s):  
Atrial Fibrillation ◽  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Thrombotic Microangiopathy ◽  
Rare Presentation ◽  
Thrombocytopenic Purpura

Cannabis used as both for medicine as well as recreational purposes. Extensive use is associated with many documented central nervous system and hepatic manifestation. How-ever only few cases are reported in literature with cardiac and hematological manifestation. Our case report is one of its kinds where our patient presents with thrombotic thrombocytopenic purpura and atrial fibrillation and he required extensive treatment including plasmapharesis.

Clinical observation of a patient with thrombotic thrombocytopenic purpura with renal and intestinal lesions

2019 ◽  
Vol 91 (7) ◽  
pp. 106-110
Author(s):  
A G Stolyar ◽  
P V Avdonin ◽  
I E Valamina ◽  
E S Stolyarevich
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Thrombotic Microangiopathy ◽  
Clinical Observation ◽  
Pathological Process ◽  
Thrombocytopenic Purpura ◽  
Intestinal Lesions ◽  
The Central Nervous System ◽  
Genetic Form

The article presents a brief description of a rare disease - thrombotic thrombocytopenic purpura (Moshkovits - disease), which is based on the deficiency of ADAMTS-13 metalloproteinase, leading to the development of thrombotic microangiopathy with the defeat of vital organs. The article also describes the clinical observation of a patient with the Moshkovits - disease. The features of the above observation are involvement in the pathological process of the kidneys and intestines, while in the classical descriptions of the disease there is a predominant lesion of the Central nervous system, as well as the genetic form of the disease.

Rare Presentation of a Relapsing Remitting Central Nervous System Vasculitis: A Case Report.

2019 ◽  
Vol 87 (02) ◽  
pp. 129-132
Author(s):  
Maksymilian Brzezicki ◽  
Matthew Kobetic ◽  
Dillon Serena
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Central Nervous System Vasculitis ◽  
Rare Presentation ◽  
Relapsing Remitting

ZusammenfassungWir berichten über einen interessanten Fall einer Vaskulitis des zentralen Nervensystems, der eine schubförmig-remittierende Natur und ein bisher nicht berichtetes Profil kognitiver Defizite bei dieser Variante der Erkrankung aufweist.Der Patient stellte sich mit beidseitigem Kopfschmerz, Gesichtsfeldverlust des linken Auges, Dyschromatopsie und vorübergehender Bewusstlosigkeit vor. Er wurde in den letzten acht Jahren auf ähnliche Symptome untersucht. Es gab eine klare schubförmig-remittierende Geschichte, mit Perioden voller Remission von 4-6 Monaten.MRT-Untersuchungen zeigten bilaterale Bereiche von Hyperintensitäten, repräsentativ für kleine „nicht-charakteristische“ Veränderungen, wahrscheinlich vaskulären Ursprungs.In diesem Bericht wird die klinische Konundra während der Evaluation des Patienten diskutiert, mögliche Differentialdiagnosen untersucht und über die hypothetische Rolle der Statinverwendung in ähnlichen Fällen kommentiert.

Thrombotic thrombocytopenic purpura with typical pentalogy in a child: a case report and literature review

2021 ◽  
Author(s):  
Qian Wan ◽  
Yao Ye ◽  
Xiaohong Zhong ◽  
Zhongjin Xu ◽  
Jian Li
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Renal Insufficiency ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Hemolytic Anemia ◽  
Thrombotic Microangiopathy ◽  
Typical Case ◽  
Microangiopathic Hemolytic Anemia ◽  
Thrombocytopenic Purpura ◽  
Life Threatening

Abstract Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic microangiopathy with clinical quintuple symptoms, including fever, thrombocytopenia, microangiopathic hemolytic anemia, neurological symptoms, and renal insufficiency. TTP onset in children is rare, and the percentage of acute TTP with these five symptoms at the same time is <10%. In this study, we reported a typical case of TTP onset in a child with clinical quintuple symptoms.

scholarly journals Extraosseous Multiple Myeloma: Case Report of Presentation in the Lower Extremity Soft Tissues with Literature Review

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Jeff Ames ◽  
Ahmad Al-Samaraee ◽  
Takashi Takahashi
Keyword(s):  
Central Nervous System ◽  
Multiple Myeloma ◽  
Nervous System ◽  
Case Report ◽  
Literature Review ◽  
Soft Tissues ◽  
Upper Airway ◽  
Solitary Plasmacytoma ◽  
Rare Presentation ◽  
Anatomic Distribution

A rare presentation of extramedullary multiple myeloma in the soft tissues of the bilateral thighs prompted a literature review of published cases of extramedullary multiple myeloma (EM-MM) and solitary plasmacytomas to determine the relative anatomic distribution of these lesions. All available published cases in English were included in the analysis, dating back to 1966 and including 2,538 extramedullary myeloma or solitary plasmacytoma lesions. Analysis of the anatomic location of EM-MM lesions demonstrates the majority being in the upper airway (33.8%), soft tissues including retroperitoneum and abdomen (14.1%), gastrointestinal tract (10.3%), central nervous system, head and neck (16.0%), and GU (2.4%). We were able to find only 44 documented cases of extremity soft tissue lesions, comprising 1.7% of all lesions.

Central Nervous System Involvement in Thrombotic Thrombocytopenic Purpura

1998 ◽  
Vol 40 (4) ◽  
pp. 220-224 ◽  
Author(s):  
A. Druschky ◽  
F. Erbguth ◽  
R. Strauss ◽  
G. Helm ◽  
J. Heckmann ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Central Nervous System Involvement ◽  
Thrombocytopenic Purpura ◽  
System Involvement

scholarly journals EXTENSIVELY DISSEMINATED CYSTICERCOSIS – CASE REPORT AND REVIEW OF LITERATURE

2020 ◽  
pp. 68-69
Author(s):  
Navdeep Kaur ◽  
Narinder Kaur ◽  
Harvinder Singh Chhabra ◽  
Ravinder Kaur
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Clinical Manifestations ◽  
Brain Parenchyma ◽  
Review Of Literature ◽  
Rare Presentation ◽  
Subcutaneous Nodules ◽  
The Central Nervous System ◽  
High Index Of Suspicion

Cysticercosis is a known disease of the developing world and accounts for the majority of epilepsy cases in these nations. The disseminated form represents a rare presentation of the disease with neurocysticercosis being the most common. Patients may present with neurological complaints of seizures only with no clinical manifestations of muscular pseudohypertrophy or palpable subcutaneous nodules usually found in disseminated form falsely localizing disease to the central nervous system. This case report highlights the fact that despite its rarity a high index of suspicion for disseminated form should be kept in mind in endemic areas and warrants routine screening of all patients for multi-organ involvement who present with multiple lesions in brain parenchyma.

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