On Some Issues of Legal Regulation of the Pharmaceutical Retail Market: the Concept of “Pharmacy Chains”, Special Antitrust Laws and Control Mechanisms

2021 ◽  
pp. 80-86
Author(s):  
A. N. Varlamova
Keyword(s):  
Product Market ◽  
Legal Regulation ◽  
Pharmaceutical Market ◽  
Control Mechanisms ◽  
Retail Market ◽  
Preferential Treatment ◽  
Antitrust Laws ◽  
Competitive Relations ◽  
And Control

Competition in the pharmaceutical market is a necessary factor providing an opportunity for citizens to purchase quality goods at affordable prices. Regulation of competitive relations in the market in question can and should have its own characteristics. Opposing monopolization of the retail market by pharmacy chains, setting “reasonable” prices, providing preferential treatment for Russian manufacturers in the promotion of goods are the issues that the legislator should pay attention to when improving regulation of this industry product market.

Sea Disposal of Sludge – The U.K. Experience

1983 ◽  
Vol 15 (1) ◽  
pp. 77-87 ◽  
Author(s):  
Hugh Fish
Keyword(s):  
Sewage Sludge ◽  
Environmental Damage ◽  
Control Mechanisms ◽  
And Control

A broad summary is made of the U.K. experience in sea-disposal of sewage sludge, embracing operations and effects, and control mechanisms, at disposal authority, national and international levels. The conclusion is reached that U.K. practice, while not perfect and in need of more research, is satisfactory and could be extended without causing environmental damage.

scholarly journals Creating and Maintaining Structural Hindrances to Criminal Justice Control – A Policy Analysis on the Normalisation of Parental Violence as a Crime in Finland

2021 ◽  
pp. 096466392110208
Author(s):  
Riikka Kotanen
Keyword(s):  
Criminal Justice ◽  
Criminal Law ◽  
Interpersonal Violence ◽  
Legal Regulation ◽  
Division Of Labour ◽  
Legal Form ◽  
Parental Violence ◽  
Control Policies ◽  
And Control

In the context of home, violence remains more accepted when committed against children than adults. Normalisation of parental violence has been documented in attitudinal surveys, professional practices, and legal regulation. For example, in many countries violent disciplining of children is the only legal form of interpersonal violence. This study explores the societal invisibility and normalisation of parental violence as a crime by analysing legislation and control policies regulating the division of labour and involvement between social welfare and criminal justice authorities. An empirical case study from Finland, where all forms of parental violence were legally prohibited in 1983, is used to elucidate the divergence between (criminal) law and control policies. The analysis demonstrates how normalisation operates at the policy-level where, within the same system of control that criminalised these acts, structural hindrances are built to prevent criminal justice interventions.

scholarly journals Probing the Interactions of Porphyrins with Macromolecules Using NMR Spectroscopy Techniques

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1942
Author(s):  
Ilche Gjuroski ◽  
Julien Furrer ◽  
Martina Vermathen
Keyword(s):  
Nmr Spectroscopy ◽  
Photophysical Properties ◽  
Optical Methods ◽  
Spectroscopic Techniques ◽  
Control Mechanisms ◽  
Dynamic Information ◽  
Non Covalent Interactions ◽  
And Control ◽  
And Diffusion ◽  
Covalent Interactions

Porphyrinic compounds are widespread in nature and play key roles in biological processes such as oxygen transport in blood, enzymatic redox reactions or photosynthesis. In addition, both naturally derived as well as synthetic porphyrinic compounds are extensively explored for biomedical and technical applications such as photodynamic therapy (PDT) or photovoltaic systems, respectively. Their unique electronic structures and photophysical properties make this class of compounds so interesting for the multiple functions encountered. It is therefore not surprising that optical methods are typically the prevalent analytical tool applied in characterization and processes involving porphyrinic compounds. However, a wealth of complementary information can be obtained from NMR spectroscopic techniques. Based on the advantage of providing structural and dynamic information with atomic resolution simultaneously, NMR spectroscopy is a powerful method for studying molecular interactions between porphyrinic compounds and macromolecules. Such interactions are of special interest in medical applications of porphyrinic photosensitizers that are mostly combined with macromolecular carrier systems. The macromolecular surrounding typically stabilizes the encapsulated drug and may also modify its physical properties. Moreover, the interaction with macromolecular physiological components needs to be explored to understand and control mechanisms of action and therapeutic efficacy. This review focuses on such non-covalent interactions of porphyrinic drugs with synthetic polymers as well as with biomolecules such as phospholipids or proteins. A brief introduction into various NMR spectroscopic techniques is given including chemical shift perturbation methods, NOE enhancement spectroscopy, relaxation time measurements and diffusion-ordered spectroscopy. How these NMR tools are used to address porphyrin–macromolecule interactions with respect to their function in biomedical applications is the central point of the current review.

scholarly journals Power Sharing and Control Strategy for Provisionally Coupled Microgrid Clusters through an Isolated Power Exchange Network

Energies ◽  
2021 ◽  
Vol 14 (22) ◽  
pp. 7514
Author(s):  
S.M. Ferdous ◽  
Farhad Shahnia ◽  
GM Shafiullah
Keyword(s):  
Power Sharing ◽  
Frequency Deviation ◽  
Load Shedding ◽  
Control Mode ◽  
Control Technique ◽  
Communication Link ◽  
Control Mechanisms ◽  
Power Exchange ◽  
Exchange Network ◽  
And Control

The two common mechanisms of load-shedding and renewable curtailment can prevent provisional overloading and excessive generation and the subsequent unacceptable voltage and frequency deviation in standalone microgrids (MGs), which makes MGs less resilient and reliable. However, instead of enabling load-shedding or renewable curtailment, such overloading or over-generation problems can be alleviated more efficiently and cost-effectively by provisionally interconnecting the neighboring MGs to exchange power amongst themselves. In such a scheme, the interconnected MGs can supply their local demand, as well as a portion of the demand of the adjacent MGs. In order to implement this strategy, a three-phase ac link can be used as the power exchange network, while each MG is coupled to the link through a back-to-back power electronics converter, in order to maintain the autonomy of each MG if they are eachoperated under different standards. This paper proposes a suitable decentralized power management strategy without a communication link between the MGs to achieve power-sharing amongst them and alleviate unacceptable voltage and frequency deviation along with the required control technique for the power electronic converters, which can be implemented at the primary level based on the measurement of the local parameters only. To this end, one of the converters should always regulate the dc link voltage while the other converter should operate in droop control mode when the MG is healthy and in constant PQ mode when overloaded or over-generating. Suitable status detection and mode transition algorithms and controllers were also developed and are proposed in this paper. The performance of the proposed power exchange and control mechanisms were evaluated and verified via PSIM®-based numerical simulation studies. The stability and sensitivity of the proposed power exchange topology are also analyzed against several critical design and operational parameters.

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