scholarly journals Breast Hamartoma: A Size Diversity with Psychosocial Impact Analysis of 20 Cases and an Exceptional Case Report Review

Objectives: Breast hamartoma is a rare painless benign tumor with limited literature review due to underestimation by clinicians and pathologists. Though slowly growing, delay in diagnosis can lead to physical and psychological impact due to breast size discrepancy. Our study intend was to present breast hamartoma concerning size variance from hardly palpable to gross defacement and its psychosocial impact due to physical disfigurement, along with a case report. Method: We reviewed the demographic data, radiological imaging, and size variability of patients diagnosed with breast hamartoma between May 2006 and November 2019. Results: Overall, 37 cases of female breast hamartoma were operated from 2006 to 2019 but only 20 cases, whose data can be retrieved, in Liaquat National Hospital & Medical College, Karachi Department of General Surgery were included in the study. The mean age of patients was 35±11.92 years. The clinical and histopathological size was 6.12 ±4.44 and 7.88 ±4.23 respectively. Largest recorded size was 20x20cm. There are 65% of cases with less than 40 years and 35% cases with greater than 45 years. Breast ultrasound and Mammograms were performed below 40 years and greater than 40 years age of respectively. Furthermore, one case presented with skin necrosis and necrotizing wound infection underwent wound debridement and later on reduction mammoplasty with hamartoma excision of 2.5 kg. Conclusion: Breast hamartomas are rare benign lesions that may have rapid growth leading to breast disfigurement and must be addressed vigilantly either by close observation or early intervention. Ultrasound has a significant role in diagnosis whereas the role of fine-needle aspiration is questionable.

2021 ◽  
pp. 231-233
Author(s):  
Siddharth Panikkar ◽  
Gigy Varkey Kuruttukulam ◽  
Manju Manmadhan ◽  
Jithin Antony Bose ◽  
Jacob Chacko ◽  
...  

Since its debut in the 1960s, the broad use and availability of benzodiazepines has mirrored the increased incidence of overdose cases. Due to its non-specic presentation, there is often a delay in diagnosis. We report a case of Benzodiazepine toxicity in a 70-year-old man who presented to us in a comatose state. He was evaluated at another hospital initially and was intubated in view of his low Glasgow Coma scale. A CT brain plain study was done suspecting a basilar artery thrombus and he was referred to us for Neuro-Interventional procedures. As radiological, laboratory and electrophysiological investigations were unremarkable a provisional diagnosis of drug intoxication was made after patient medication review and a trial of Flumazenil was given, after which the patient had improved dramatically. Flumazenil is not routinely used due to fears of withdrawal seizures and its high cost. It also has no effect on reversing sedation caused by barbiturates, ethanol, or opioids. The antidote has a favorable risk-benet ratio when dosed appropriately and can be a helpful diagnostic tool after ruling out the more common causes of acute sensorium loss as demonstrated by this case report.


2016 ◽  
Vol 22 (3) ◽  
pp. 145-148
Author(s):  
Alparslan Yetişgin ◽  
Ahmet Boyacı ◽  
Ahmet Tutoğlu ◽  
Ahmet Hartavi

2020 ◽  
Vol 10 (6) ◽  
pp. 156-157
Author(s):  
Muhammet Mesut Nezir ENGİN ◽  
Fatih ERDOĞAN ◽  
Özlem KÜÇÜK ◽  
Murat KAYA

Foreign body aspiration (FBA) is common in children. Especially in children, the majority of accidental deaths occur due to FBA. Morbidity and mortality rates increase, especially in children between the ages of one and four, and as a result of delay in diagnosis. The most common symptoms in patients with FBA are cough, dyspnea, hemoptysis, stridor and wheezing. In this case report, a patient who presented with sudden respiratory distress in the Pediatric Emergency Department was presented and the importance of anamnesis and respiratory examination in the diagnosis of FBA was emphasized.


2020 ◽  
Vol 54 (3) ◽  
pp. 201-203
Author(s):  
Michael Ezeanochie ◽  
Oghenefegor Olokor ◽  
Ofure Yamah

Acute fatty liver of pregnancy (AFLP) is an uncommon condition that manifests in the third trimester of pregnancy.Its association with vaso-occlusive crisis from Sickle Cell Anaemia is not common. Published data on the simultaneous occurrence of these two conditions is rare, hence this case report. A 32-year-old gravida 3 para 1+1 lady, with Sickle Cell Anaemia, had a vaso-occlusive crisis in association with AFLP at 32 weeks’ gestation, and the outcome of her management was successful. AFLP is a rare late-gestational event affecting about 1 in 10,000 to 15,000 pregnancies. The exact aetiology is not known. Profound hypoglycaemia and jaundice with elevated serum transaminases are recognized features of AFLP.These features may also be seen in haemoglobinopathies. The simultaneous occurrence of AFLP and Sickle Cell Anaemia may result in overlap of symptoms and delay in diagnosis and treatment. Therefore, maintaining a high index of suspicion is key. The cornerstone for treatment remains prompt delivery and supportive care. AFLP can coexist with Sickle cell crises. It is important that care providers, especially in populations with high burden of Sickle Cell Anaemia, consider this as a differential diagnosis, especially when the jaundice is associated with profound or recurring episodes of hypoglycaemia. Prompt diagnosis and delivery in a multidisciplinary approach is important to avoid adverse maternal and foetal outcomes.Keywords: Vaso-occlusive crises, acute fatty liver of pregnancy, hypoglycaemia, Sickle-cell anaemiaFunding: No funding sources


Author(s):  
Glizevskaja Julia ◽  
Abbas Mohammed ◽  
Nwaejike Nnamdi

2019 ◽  
Vol 25 (5) ◽  
pp. 579-584 ◽  
Author(s):  
Maksim Shapiro ◽  
Ilya Kister ◽  
Eytan Raz ◽  
John Loh ◽  
Matthew Young ◽  
...  

Spinal dural fistulas (SDAVFs) occasionally arise from the same segmental artery as the radiculomedullary branch to the anterior spinal artery. In such cases, selective fistula embolization that does not endanger the anterior spinal artery is not possible, and surgical fistula disconnection is recommended. We present an exceptional case in which rational embolization strategy of SDAVF was feasible because of separate origins from a common segmental artery pedicle of the ventral radiculomedullary artery and the dorsal radicular artery branch supplying the fistula.


2005 ◽  
Vol 89 (2) ◽  
pp. 145-147 ◽  
Author(s):  
Giovanna Gatti ◽  
Giovanni Mazzarol ◽  
Serife Simsek ◽  
Giuseppe Viale
Keyword(s):  

2016 ◽  
Vol 117 (1) ◽  
pp. 341-343 ◽  
Author(s):  
Rahma Beyrouti ◽  
Malek Mansour ◽  
Amel Kacem ◽  
Hager Derbali ◽  
Ridha Mrissa

2008 ◽  
Vol 2 (2) ◽  
Author(s):  
J K Olabanji ◽  
B J Olasode ◽  
A A Salako ◽  
I A Alatise ◽  
B M Ibitoye ◽  
...  

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