Chronic Glycemic Control in Surgical Patients admitted at a Tertiary Care Hospital

Background: COVID-19 disease caused by SARS-COV-2 has become a pandemic. Outcome of surgical patients infected with COVID-19 is not very clear.Methods: Retrospective analysis of the surgical outcome of COVID-19 infected patients admitted in emergency and elective surgical settings in a designated COVID care center.Results: Total 53 patients were included. Surgery was done in 47.16% (n=25) patients and 52.84% (n=28) patients were managed non-operatively. Overall mortality was 37.7 % (n=20). In operated group it was 52% (n=13) and 25% (n=7) in the non-operative group (p=0.043). The total leukocyte (p=0.018), serum CRP (p=0.031), urea and creatinine level (p=0.025) were higher in the mortality group. Patients aged more than 50 years had a significantly higher mortality compared to less than 50 years (p=0.010). Patients having multiple comorbidities had higher mortality (p=0.159).Conclusions: COVID-19 infection has a definite adverse impact on the outcomes of surgical patients.

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Study of prescription pattern of antimicrobials used in post-operative surgical patients in tertiary care hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20212068 ◽

2021 ◽

Vol 10 (6) ◽

pp. 627

Author(s):

Jitendra H. Hotwani ◽

Nishikant H. Madkholkar

Keyword(s):

Tertiary Care Hospital ◽

Tertiary Care ◽

Total Duration ◽

Hospital Setting ◽

Surgical Site Infections ◽

The Body ◽

Brand Names ◽

Surgical Patients ◽

Care Hospital ◽

Prescription Pattern

Background: Antimicrobials are used for prophylaxis and treatment of infections which occur following surgical procedures, to reduce the morbidity and mortality associated with surgical site infections (SSIs). A surgical site infection is an infection that occurs after surgery in the part of the body where the surgery took place. These are infections of the tissues, organs, or spaces exposed by surgeons during performance of an invasive procedure.Methods: A prospective, non-interventional, observational study in tertiary care hospital for duration of 9 months. Sample size was 330.Results: The prescription pattern shows that nitroimidazoles were the most commonly prescribed group of antimicrobials in 72% of patients followed by penicillins (58%) and cephalosporins (42%). Metronidazole (72%), amoxicillin and clavulanic acid (51.21%) ceftriaxone (20.90%) were most commonly prescribed antimicrobials in these groups. Two antimicrobials were prescribed in 47% patients with nitroimidazole and penicillins being the most commonly prescribed combination of antimicrobial. Three antimicrobials were prescribed in 25% patients and four antimicrobials in 8% patients. This shows trend towards polypharmacy. About 82% of antimicrobials were prescribed by brand names and 64% of total antimicrobials prescribed from outside the hospital pharmacy source. About 12.42% of patients changed antimicrobial therapy after culture and sensitivity report.Conclusions: Total duration, number of anti-microbial used was more in clean-contaminated, contaminated, dirty wound surgeries as compare to clean wound surgeries. Our study provides a framework for continuous prescription audit of antimicrobials in a hospital setting and thus can help in rational use of antimicrobials in post-operative surgical patients.

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Concurrent And Longitudinal Association Between Glycemic Control And Self Reported Medication Adherence Among Type 2 Diabetes Patients At A Tertiary Care Hospital In Malaysia

Current Diabetes Reviews ◽

10.2174/1573399814666180828152754 ◽

2019 ◽

Vol 15 (5) ◽

pp. 402-406

Author(s):

Mubashra Butt ◽

Adliah Mhd Ali ◽

Mohd Makmor Bakry

Keyword(s):

Type 2 Diabetes ◽

Medication Adherence ◽

Glycemic Control ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Care Hospital ◽

Longitudinal Observation ◽

Longitudinal Association ◽

Diabetes Patients

Background: This study evaluated the association between self-reported adherence with concurrent and subsequent glycemic control amongst type 2 diabetes patients at a tertiary care hospital in Malaysia. Methods: Demographic and clinical variables were assessed at baseline, after three and six months in 73 type 2 diabetes patients. Regression analysis, using SPSS, evaluated the concurrent and longitudinal association of medication adherence and glycemic control. Potential confounders of variables were identified using bi-variate correlation analyses. Results: Concurrent Medication adherence and HbA1c association were significant after adjusting for ethnicity (P = 0.005). For longitudinal observation at 3 months, the association was significant after adjusting for ethnicity (P = 0.016); however, it became non-significant when baseline glycemic control was included in the model (P = 0.28). Conclusion: Easy to administer MALMAS significantly predicted concurrent glycemic control independent of potential confounders. This association persisted in longitudinal observation after 3 months when adjusted for confounders and became non-significant after adjusting for baseline glycemic control.

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