Spindle Cell Hemangioma of the Nasal Cavity: A Rare Tumor with Unusual Presentation

ABSTRACT Vascular tumors as such are rare in the nasal cavity. Few cases of lobular capillary hemangioma, cavernous hemangioma and epitheloid hemangioendothelioma have been reported in the nasal cavity. But, there are no reports of spindle cell hemangioma occurring within the nasal cavity. They usually present as subcutaneous nodules in the extremities. A case of recurrent bleeding polypoid lesion in the left nasal cavity, arising from the middle turbinate which showed features of spindle cell hemangioma is reported for its rarity and unusual presentation. The tumor was excised by minimally invasive transnasal endoscopic approach. How to cite this article Suranagi V, Harugop AS, Bannur HB, Pilli GS, Mudhol RS. Spindle Cell Hemangioma of the Nasal Cavity: A Rare Tumor with Unusual Presentation. Clin Rhinol An Int J 2013;6(3):149-151.

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IMMUNOHISTOCHEMISTRY IN DIAGNOSIS OF EXTRANASOPHARYNGEAL ANGIOFIBROMA ORIGINATING FROM NASAL CAVITY: CASE PRESENTATION AND REVIEW OF THE LITERATURE

Acta Medica (Hradec Kralove Czech Republic) ◽

10.14712/18059694.2014.8 ◽

2013 ◽

Vol 56 (4) ◽

pp. 133-141 ◽

Cited By ~ 8

Author(s):

Aleksandar Perić ◽

Jelena Sotirović ◽

Snežana Cerović ◽

Ljubica Živić

Keyword(s):

Nasal Cavity ◽

Middle Turbinate ◽

Immunohistochemical Analysis ◽

Capillary Hemangioma ◽

Vascular Lesions ◽

Vascular Tumors ◽

Lobular Capillary Hemangioma ◽

Male Adolescents ◽

Extranasopharyngeal Angiofibroma ◽

Google Search

Angiofibromas are rare vascular tumors which originate predominantly in the nasopharynx and occur typically in male adolescents. Extranasopharyngeal sites such as nasal cavity and paranasal sinuses are less frequent. This review article was undertaken to evaluate the incidence, clinical features and management of extranasopharyngeal angiofibromas originating exclusivelly from nasal cavity structures. Our focus of interest was to evaluate the significance of immunohistochemical analysis in diagnosis of such extremely rare neoplasms. In the PubMed and Google Search, we found only 39 cases of nasal angifibroma, 27 males and 12 females from 1980 to 2012. The most prevalent site of origin was nasal septum, followed by inferior and middle turbinate. The commonest symptoms were nasal obstruction and epistaxis. Nasal angiofibromas are clinically distinct from nasopharyneal angiofibromas and can therefore be misdiagnosed. The differential diagnosis includes other vascular lesions, such as lobular capillary hemangioma and sinonasal-type hemangiopericytoma. Although immunohistochemistry is not necessary for differentiation between angiofibroma and capillary hemangioma, that diagnostic procedure may be helpful in distinction from sinonasal hemangiopericytoma. As an ilustration for immunohistochemical analysis, we presented a case of an elderly woman with tumor arising from the middle turbinate, diagnosed as angiofibroma. The staining was positive for CD34, CD31, factor VIII, vimentin and smooth muscle α-actin, and negative for desmin.

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Middle turbinate angiofibroma in an elderly woman

Vojnosanitetski pregled ◽

10.2298/vsp0907583p ◽

2009 ◽

Vol 66 (7) ◽

pp. 583-586 ◽

Cited By ~ 11

Author(s):

Aleksandar Peric ◽

Nenad Baletic ◽

Snezana Cerovic ◽

Biserka Vukomanovic-Djurdjevic

Keyword(s):

Nasal Cavity ◽

Elderly Woman ◽

Anterior Part ◽

Middle Turbinate ◽

Immunohistochemical Analysis ◽

Vascular Tumors ◽

Male Adolescents ◽

Sphenopalatine Foramen ◽

First Case ◽

Left Middle

Background. Angiofibromas are histologically benign vascular tumors, originating from the nasopharynx, near by the area of sphenopalatine foramen. These neoplasms occur typically in male adolescents. Reports of primary extranasopharyngeal angiofibromas have appeared sporadically in the literature in English. We present the first case of an elderly woman with tumor arising from the middle turbinate, diagnosed as angiofibroma. Case report. A 63-year-old female presented with left-sided nasal obstruction and epistaxis. Endoscopic evaluation revealed a polypoid mass arising from the anteroinferior portion of the left middle turbinate. Computed tomography (CT) scan showed a soft-tissue opacity that filled the anterior part of the left nasal cavity. After the endoscopic excision of the mass, postoperative pathohistological and immunohistochemical analysis confirmed the diagnosis of an angiofibroma. Two years later, the patient was free of symptoms and without endoscopic evidence of recurrence. Conclusion. Extranasopharyngeal angiofibromas arising from the nasal cavity are extremely rare tumors. Immunohistochemical analysis is very important in all doubtful cases, especially in those with atypical location.

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A rare case of pediatric intranasal lobular capillary hemangioma

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20204641 ◽

2020 ◽

Vol 6 (11) ◽

pp. 2115

Author(s):

Sam D. Schild ◽

Rachel Irizarry ◽

Ann Plum

Keyword(s):

Nasal Cavity ◽

Surgical Excision ◽

Vascular Lesion ◽

Capillary Hemangioma ◽

Vascular Tumors ◽

Preoperative Embolization ◽

Mri Imaging ◽

En Bloc ◽

Lobular Capillary Hemangioma ◽

The Right

<p class="abstract">Pediatric nasal cavity vascular tumors express a wide variety of pathologies. Lobular capillary hemangioma (LCH) is an acquired benign vascular growth of skin and mucosa whose etiology remains unknown, though trauma and hormonal influences are implicated. Although well documented in the head and neck literature for children age five or less, it is a rarity within the nasal cavity and has yet to be documented in the mid-septum. We describe a unique case of intranasal LCH and review the current literature. A nine-year-old male presented with one week of profuse intermittent unilateral epistaxis and no history of nasal trauma. Rhinoscopy revealed a pink, pedunculated mass of the right mid-nasal septum at the bony-cartilaginous junction. CT and MRI imaging were consistent with an expansile vascular lesion receiving prominent bilateral sphenopalatine artery supply. Following embolization, en bloc endoscopic surgical excision of the lesion using cold dissection was performed with no bony or cartilaginous involvement noted. The epistaxis resolved following resection. Final histology confirmed the mass as a lobular capillary hemangioma. Paediatric intranasal LCH is a rare entity, yet warrants consideration in our differential diagnosis of pediatric vascular tumors. Our study indicates these lesions can develop in the mid-septum despite the absence of a vascular plexus. Preoperative embolization should be considered for pediatric nasal cavity tumors due to concern for hemorrhage. Endoscopic wide local excision is an appropriate and effective treatment. </p>

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Intranasal Lobular Capillary Hemangioma with Multiple Sites of Origin during Pregnancy: A Case Report and Literature Review

Case Reports in Otolaryngology ◽

10.1155/2018/7413918 ◽

2018 ◽

Vol 2018 ◽

pp. 1-5

Author(s):

Lama S. Alalula ◽

Abdullah S. Arafat ◽

Riyadh A. Alhedaithy ◽

Mohammed Elkrim

Keyword(s):

Case Report ◽

Nasal Cavity ◽

Symptomatic Relief ◽

Middle Turbinate ◽

Posterior Part ◽

Capillary Hemangioma ◽

Surgical Removal ◽

En Bloc ◽

Lobular Capillary Hemangioma ◽

Recurrent Epistaxis

In the present case report, we describe a 33-year-old pregnant woman in the third trimester with a history of recurrent epistaxis leading to frequent visits to the emergency department. Each episode of epistaxis was managed by anterior nasal packing. During endoscopic examination, a left nasal mass was seen. She was admitted and managed conservatively until she delivered her baby without complication. After delivery, a CT scan was taken, which showed an enhancing mass in the middle and lower meatus of the nasal cavity with no bony erosions. For symptomatic relief and tissue diagnosis, endoscopic surgical removal was advised. An intraoperative examination revealed a red, smooth, and well-circumscribed mass occupying the left nasal cavity and originating from the medial surface of the inferior turbinate and the inferior surface of the posterior part of the middle turbinate. A complete en bloc resection of the mass was performed endoscopically. The mass was sent for histologic analysis, which confirmed the diagnosis of lobular capillary hemangioma. Eventually, upon follow-up at two weeks, one month, three months, and six months postsurgery, no evidence of recurrence was detected.

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Spindle cell hemangioma: Unusual presentation of an uncommon tumor

Journal of Oral and Maxillofacial Pathology ◽

10.4103/0973-029x.174634 ◽

2015 ◽

Vol 19 (3) ◽

pp. 406 ◽

Cited By ~ 6

Author(s):

OlalereOmoyosola Gbolahan ◽

Oluyemi Fasina ◽

AkinyeleOlumuyiwa Adisa ◽

OlubayoA Fasola

Keyword(s):

Spindle Cell ◽

Unusual Presentation ◽

Spindle Cell Hemangioma ◽

Uncommon Tumor

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Lobular Capillary Hemangioma of Nasal Cavity

Clinical Rhinology An International Journal ◽

10.5005/jp-journals-10013-1098 ◽

2011 ◽

Vol 4 (3) ◽

pp. 152-153

Author(s):

Vaneeta Bhardwar ◽

Kulbir Kaur ◽

Sonia Arora

Keyword(s):

Nasal Cavity ◽

Nasal Obstruction ◽

Benign Lesion ◽

Middle Turbinate ◽

Capillary Hemangioma ◽

Diagnosis And Treatment ◽

Unknown Etiology ◽

Lobular Capillary Hemangioma

ABSTRACT Nasal lobular capillary hemangioma is a benign lesion of unknown etiology. Epistaxis and nasal obstruction are the most marked symptoms. We present a case of lobular capillary hemangioma, which was located on the posterior end of middle turbinate. The case is reported for its potential for being misdiagnosed and to highlight the advantage of nasal endoscopes in diagnosis and treatment.

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Spindle Cell Carcinoma of the Tongue: A Rare Tumor in an Unusual Location

Pathology Research International ◽

10.4061/2011/572381 ◽

2011 ◽

Vol 2011 ◽

pp. 1-6 ◽

Cited By ~ 2

Author(s):

Murat Oktay ◽

Tuba Dilay Kokenek-Unal ◽

Bulent Ocal ◽

Guleser Saylam ◽

Mehmet Hakan Korkmaz ◽

...

Keyword(s):

Cell Carcinoma ◽

Spindle Cell ◽

Polypoid Lesion ◽

Spindle Cell Carcinoma ◽

Tumor Type ◽

Rare Tumor ◽

Unusual Location ◽

Rare Malignancy ◽

Biphasic Tumor ◽

Carcinoma Of The Tongue

Spindle cell carcinoma is a rare biphasic tumor consisting of epithelial and mesenchymal components. Presence of this tumor type in the tongue has rarely been reported. Herein, a case of 55-year-old woman who presented with a polypoid lesion at her tongue has been reported. Surgery was performed and pathologic examination revealed a spindle cell carcinoma. We present this rare tumor with an unusual location to contribute in part to the better understanding and awareness of this rare malignancy.

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Intramedullary spindle cell hemangioma: case report

Journal of Neurosurgery Spine ◽

10.3171/2015.11.spine15641 ◽

2016 ◽

Vol 25 (3) ◽

pp. 379-382

Author(s):

Rani Nasser ◽

Kimberly Ashayeri ◽

Alan D. Legatt ◽

John K. Houten

Keyword(s):

Spinal Cord ◽

Spindle Cell ◽

Biological Behavior ◽

Rare Tumor ◽

Loss Of Function ◽

Total Resection ◽

Intramedullary Spinal Cord ◽

Intradural Extramedullary ◽

Spindle Cell Hemangioma

The authors describe the case of a 48-year-old man found to have the first reported intramedullary spinal cord spindle cell hemangioma. Previous research indicates that spindle cell hemangiomas are rarely found in the spine. Only 3 previous cases exist, all in the intradural, extramedullary space. In the present case, gross-total resection of the tumor was possible with no loss of function from baseline. This report presents the successful resection of the first reported intramedullary spindle cell hemangioma and reports 4-month follow-up, demonstrating the biological behavior of this rare tumor.

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Malignant Peripheral Nerve Sheath Tumor in the Nasal Cavity of a Neonate: A Case Report

Ear Nose & Throat Journal ◽

10.1177/01455613211014103 ◽

2021 ◽

pp. 014556132110141

Author(s):

Xiufang Chi ◽

Yue Wang ◽

Haoming Yang ◽

Cheng Xing ◽

Jiamin Gan ◽

...

Keyword(s):

Differential Diagnosis ◽

Peripheral Nerve ◽

Nasal Cavity ◽

Nerve Fibers ◽

Nerve Sheath Tumor ◽

Rare Tumor ◽

Nasal Mass ◽

Peripheral Nerve Sheath Tumor ◽

Related Literature ◽

Nerve Sheath

Malignant peripheral nerve sheath tumor (MPNST) is a rare tumor that can develop on the lining of nerves and within the network of nerve fibers in different organs, and it is commonly found in the head and neck, limbs, and trunk. These tumors can occur in patients of any age. They most commonly occur in adults aged 20 to 50 years; however, fewer cases of this tumor in children have been reported. To date, no neonatal case of MPNST in the nasal cavity has been reported. Here, we report the case of a 4-day-old female newborn who presented with a nasal mass that re-enlarged after surgery and was diagnosed as MPNST of the nasal cavity on the basis of pathological results. This is the first report of MPNST in the nasal cavity of a neonate. Differential diagnosis and treatment of nasal masses have been proposed in the related literature.

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