scholarly journals Middle turbinate angiofibroma in an elderly woman

2009 ◽  
Vol 66 (7) ◽  
pp. 583-586 ◽  
Author(s):  
Aleksandar Peric ◽  
Nenad Baletic ◽  
Snezana Cerovic ◽  
Biserka Vukomanovic-Djurdjevic
Keyword(s):  
Nasal Cavity ◽  
Elderly Woman ◽  
Anterior Part ◽  
Middle Turbinate ◽  
Immunohistochemical Analysis ◽  
Vascular Tumors ◽  
Male Adolescents ◽  
Sphenopalatine Foramen ◽  
First Case ◽  
Left Middle

Background. Angiofibromas are histologically benign vascular tumors, originating from the nasopharynx, near by the area of sphenopalatine foramen. These neoplasms occur typically in male adolescents. Reports of primary extranasopharyngeal angiofibromas have appeared sporadically in the literature in English. We present the first case of an elderly woman with tumor arising from the middle turbinate, diagnosed as angiofibroma. Case report. A 63-year-old female presented with left-sided nasal obstruction and epistaxis. Endoscopic evaluation revealed a polypoid mass arising from the anteroinferior portion of the left middle turbinate. Computed tomography (CT) scan showed a soft-tissue opacity that filled the anterior part of the left nasal cavity. After the endoscopic excision of the mass, postoperative pathohistological and immunohistochemical analysis confirmed the diagnosis of an angiofibroma. Two years later, the patient was free of symptoms and without endoscopic evidence of recurrence. Conclusion. Extranasopharyngeal angiofibromas arising from the nasal cavity are extremely rare tumors. Immunohistochemical analysis is very important in all doubtful cases, especially in those with atypical location.

scholarly journals IMMUNOHISTOCHEMISTRY IN DIAGNOSIS OF EXTRANASOPHARYNGEAL ANGIOFIBROMA ORIGINATING FROM NASAL CAVITY: CASE PRESENTATION AND REVIEW OF THE LITERATURE

2013 ◽  
Vol 56 (4) ◽  
pp. 133-141 ◽  
Author(s):  
Aleksandar Perić ◽  
Jelena Sotirović ◽  
Snežana Cerović ◽  
Ljubica Živić
Keyword(s):  
Nasal Cavity ◽  
Middle Turbinate ◽  
Immunohistochemical Analysis ◽  
Capillary Hemangioma ◽  
Vascular Lesions ◽  
Vascular Tumors ◽  
Lobular Capillary Hemangioma ◽  
Male Adolescents ◽  
Extranasopharyngeal Angiofibroma ◽  
Google Search

Angiofibromas are rare vascular tumors which originate predominantly in the nasopharynx and occur typically in male adolescents. Extranasopharyngeal sites such as nasal cavity and paranasal sinuses are less frequent. This review article was undertaken to evaluate the incidence, clinical features and management of extranasopharyngeal angiofibromas originating exclusivelly from nasal cavity structures. Our focus of interest was to evaluate the significance of immunohistochemical analysis in diagnosis of such extremely rare neoplasms. In the PubMed and Google Search, we found only 39 cases of nasal angifibroma, 27 males and 12 females from 1980 to 2012. The most prevalent site of origin was nasal septum, followed by inferior and middle turbinate. The commonest symptoms were nasal obstruction and epistaxis. Nasal angiofibromas are clinically distinct from nasopharyneal angiofibromas and can therefore be misdiagnosed. The differential diagnosis includes other vascular lesions, such as lobular capillary hemangioma and sinonasal-type hemangiopericytoma. Although immunohistochemistry is not necessary for differentiation between angiofibroma and capillary hemangioma, that diagnostic procedure may be helpful in distinction from sinonasal hemangiopericytoma. As an ilustration for immunohistochemical analysis, we presented a case of an elderly woman with tumor arising from the middle turbinate, diagnosed as angiofibroma. The staining was positive for CD34, CD31, factor VIII, vimentin and smooth muscle α-actin, and negative for desmin.

scholarly journals Endoscopic excision of nasal septal schwannoma:case report and review of literature

2019 ◽  
Vol 18 (3) ◽  
pp. 660-662
Author(s):  
Norsyamira Aida Mohamad Umbaik ◽  
Rosdi Ramli ◽  
Baharudin Abdullah
Keyword(s):  
Nasal Cavity ◽  
Paranasal Sinuses ◽  
Anterior Part ◽  
Medical Science ◽  
Middle Turbinate ◽  
Postoperative Recovery ◽  
Benign Tumors ◽  
Left Nasal Cavity ◽  
Myelinated Nerve ◽  
Endoscopic Excision

Schwannomas are benign tumors arising from Schwann cells of myelinated nerve sheath. Schwannomas of the nasal cavity and paranasal sinuses are rare, with only 4% occurrence. We report a case of a 48-year-old lady who presented with 1-year history of progressively worsening left nasal blockage. Rigid nasoendoscopy showed a smooth, globular mass occupying the left nasal cavity. The mass arose from the left nasal septum and impinged on the anterior part of the middle turbinate posteriorly and inferior turbinate anteriorly. Computed tomography of the paranasal sinuses showed a 3.8 × 1.8 x 3.7- cm enhancing soft tissue density in the left nostril. The mass obliterated the left nasal cavity and caused deviation of the septum to the right. The patient underwent an endoscopic excision and histopathologic examination confirmed the diagnosis of Schwannoma. Postoperative recovery was uneventful and no recurrence was seen in the follow-up period. Bangladesh Journal of Medical Science Vol.18(3) 2019 p.660-662

scholarly journals Cavernous hemangioma of left nasal meatus

2019 ◽  
Vol 5 (4) ◽  
pp. 1115
Author(s):  
Anil Hanakere Thimmaiah ◽  
Smitha Soubhagya Gangaraj ◽  
Thara Rachel Paul
Keyword(s):  
Nasal Cavity ◽  
Cavernous Hemangioma ◽  
Middle Turbinate ◽  
Inferior Turbinate ◽  
Benign Tumors ◽  
Antrochoanal Polyp ◽  
Middle Meatus ◽  
Left Nasal Cavity ◽  
Left Middle ◽  
Skin Mucosa

<p class="abstract">Hemangiomas are benign accumulations of blood vessels which occur in any tissue that includes vascular components like skin, mucosa, muscles, glands and bones. Hemangiomas arising in the nose are rare and account for less than 20% of all benign tumors of nose. They usually arise from inferior turbinate, middle turbinate and vomer. We present a case of cavernous hemangioma of left nasal cavity arising from mucosa of left middle meatus mimicking an antrochoanal polyp. Hemangiomas arising from middle meatus are extremely rare and to our knowledge this is the second case reported in literature.</p><p> </p>

scholarly journals Spindle Cell Hemangioma of the Nasal Cavity: A Rare Tumor with Unusual Presentation

2013 ◽  
Vol 6 (3) ◽  
pp. 149-151
Author(s):  
RS Mudhol ◽  
Vijayalaxmi Suranagi ◽  
Anil S Harugop ◽  
Hema B Bannur ◽  
Ganga S Pilli
Keyword(s):  
Nasal Cavity ◽  
Spindle Cell ◽  
Polypoid Lesion ◽  
Middle Turbinate ◽  
Capillary Hemangioma ◽  
Unusual Presentation ◽  
Vascular Tumors ◽  
Recurrent Bleeding ◽  
Rare Tumor ◽  
Spindle Cell Hemangioma

ABSTRACT Vascular tumors as such are rare in the nasal cavity. Few cases of lobular capillary hemangioma, cavernous hemangioma and epitheloid hemangioendothelioma have been reported in the nasal cavity. But, there are no reports of spindle cell hemangioma occurring within the nasal cavity. They usually present as subcutaneous nodules in the extremities. A case of recurrent bleeding polypoid lesion in the left nasal cavity, arising from the middle turbinate which showed features of spindle cell hemangioma is reported for its rarity and unusual presentation. The tumor was excised by minimally invasive transnasal endoscopic approach. How to cite this article Suranagi V, Harugop AS, Bannur HB, Pilli GS, Mudhol RS. Spindle Cell Hemangioma of the Nasal Cavity: A Rare Tumor with Unusual Presentation. Clin Rhinol An Int J 2013;6(3):149-151.

scholarly journals Extranasopharyngeal Angiofibroma Arising from the Anterior Nasal Septum in a 35-Year-Old Woman

2019 ◽  
Vol 12 (2) ◽  
pp. 141-145
Author(s):  
Tarik Kujundžić ◽  
Aleksandar Perić ◽  
Biserka Vukomanović Đurđević
Keyword(s):  
Nasal Cavity ◽  
Nasal Septum ◽  
English Language ◽  
Histopathological Examination ◽  
Anterior Part ◽  
Immunohistochemical Analysis ◽  
Inferior Turbinate ◽  
Vascular Lesion ◽  
Female Population ◽  
Extranasopharyngeal Angiofibroma

Angiofibroma is a relatively rare vascular lesion originating predominantly in the nasopharynx and occurs typically in male adolescents. Extranasopharyngeal sites of origin, such as nasal cavity, paranasal sinuses, pharynx, and larynx, are extremely rarely seen in clinical practice. In the nasal cavity, extranasopharyngeal angiofibromas (ENAs) have been reported to originate from the nasal septum, as well as from the middle and inferior turbinate. In this study, we report a case of a 35-year-old female patient with angiofibroma originating from the anterior part of the nasal septum with left-sided nasal obstruction and mild-to-moderate epistaxis as main complaints. After the radiological diagnostics and embolization of sphenopalatine artery, we performed the excision of the lesion with removal of small part of septal mucosa and perichondrium around the attachment of tumor pedicle. Histopathological examination suggested the presence of angiofibroma and diagnosis was confirmed by immunohistochemical analysis. This is the fifth reported case of septal ENA in female population in the English-language literature.

scholarly journals Nasal Epithelial Myoepithelial Carcinoma: An Unusual Cause of Epiphora, a Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. ar.2015.6.0127 ◽  
Author(s):  
Juliette O. Flam ◽  
Christopher D. Brook ◽  
Rachel Sobel ◽  
John C. Lee ◽  
Michael P. Platt
Keyword(s):  
Case Report ◽  
Physical Examination ◽  
Nasal Cavity ◽  
Surgical Excision ◽  
Myoepithelial Carcinoma ◽  
Review Of The Literature ◽  
Nasal Symptoms ◽  
First Case ◽  
Nasal Tumor ◽  
Epithelial Myoepithelial Carcinoma

Introduction Epithelial myoepithelial carcinoma (EMC) of the nasal cavity is a rare tumor, and here we describe the first case of EMC of the nasal cavity presenting with epiphora. A case presentation and review of the literature is provided. Methods A case report is described of a 63-year-old man who presented with unilateral epiphora and was found via a thorough history and physical examination to have a nasal tumor. The physical examination consisted of an ocular examination, including probing and irrigation, and a detailed nasal examination (anterior rhinoscopy, nasal endoscopy). The nasal examination was prompted by the patient's report of concurrent nasal symptoms during history taking. Immunohistochemistry subsequently identified the nasal tumor as EMC. A literature search was performed to gain insights into similar malignancies of the nasal cavity. Results Eight cases of EMC of the nasal cavity were identified in the literature, none of the patients presented with epiphora. The case presented here resulted in resolution of the patient's symptoms and no evidence of disease after surgical excision. Conclusion Epithelial myoepithelial is a rare salivary gland malignancy that can arise in the nasal cavity. Unilateral epiphora with concurrent nasal symptoms should prompt nasal cavity examination for the possibility of an obstructive tumor.

scholarly journals 326. Radiologic Findings of COVID-19 Associated Mucormycosis (CAM) from India

2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S268-S269
Author(s):  
Aswath Govindaraju ◽  
Deepti H Vijayakumar ◽  
Raghavendra Tirupathi ◽  
Jaffar A Al-Tawfiq ◽  
Ali A Rabaan
Keyword(s):  
Optic Neuritis ◽  
Paranasal Sinuses ◽  
Orbital Cellulitis ◽  
Pterygopalatine Fossa ◽  
Fungal Culture ◽  
Imaging Features ◽  
Middle Meatus ◽  
Sphenopalatine Foramen ◽  
Contrast Enhanced ◽  
Left Middle

Abstract Background The unique feature of the second wave of the COVID -19 pandemic in India has been the alarming surge of acute invasive fungal infection among COVID -19 patients. The increased incidence of rhino-orbito-cerebral mucormycosis is a matter of concern, as this fulminant infection has high morbidity and mortality. Hence, it is imperative to understand it’s imaging features, for early diagnosis, staging and treatment. Methods We systematically reviewed 32 COVID-19 cases with imaging diagnosis of acute invasive fungal rhino-sinusitis or rhino-orbital-cerebral disease between March to May 2021. These patients underwent contrast MRI of the paranasal sinus, orbit and brain. Contrast enhanced CT chest and paranasal sinuses were done as needed. Results The age group ranged between 30 to 71 yrs with male preponderance. The most common predisposing factors were intravenous steroid therapy and supplemental oxygen. All cases were confirmed by fungal culture and most common was Mucor. The rhino-orbito-cerebral mucormycosis was staged as below In our study we found that the most common site in the nasal cavity was the middle turbinate /meatus and the earliest sign was non-enhancing / “black” turbinate. Premaxillary and retroantral fat necrosis was the earliest sign of soft tissue invasion. Spread via the sphenopalatine foramen and pterygopalatine fossa was more common than bony erosions. Orbital cellulitis and optic neuritis were the most common among stage 3 cases. Of patients with CNS involvement, the most common were cavernous sinus thrombosis and trigeminal neuritis. Two patients with pulmonary mucormycosis showed large necrotic cavitary lesions, giving the characteristic “bird’s nest” appearance. Figure 1. Black turbinate Contrast enhanced coronal T1 FS images of paranasal sinuses shows necrotic non-enhancing right superior and middle turbinates (*) Figure 2: Axial contrast enhanced T1 FS image showing necrotic non enhancing premaxillary (arrowhead) and retroantral fat (straight arrow) walled off by thin enhancing rim. Figure 3: Contrast enhanced axial T1 FS images of paranasal sinuses shows necrotic non-enhancing left middle meatus spreading along sphenopalatine foramen in to pterygopalatine fossa (arrow head) Conclusion The mortality rate was 20% in our study. In our short term follow up, 30 % of recovered patients had relapse on imaging due to incomplete clearance and partial antifungal treatment. High clinical suspicion and low imaging threshold are vital for early Mucormycosis detection in COVID-19 patients. Familiarity with early imaging signs is critical to prevent associated morbidity /mortality. Figure 4: Contrast enhanced coronal T1 FS and diffusion weighted images shows necrotic non-enhancing left middle meatus with left orbital cellulitis (*) and optic neuritis (white arrow) Figure 5. Bird’s nest Axial CT chest image in lung window shows necrotic right upper lobe cavity with internal septations and debris on a background of surrounding COVID-19 changes. Disclosures All Authors: No reported disclosures

Comparative investigations of anatomy and physiology in mammalian noses (Homo sapiens--Artiodactyla)

2011 ◽  
Vol 49 (1) ◽  
pp. 18-23
Author(s):  
S. Grutzenmacher ◽  
D.M. Robinson ◽  
J. Sevecke ◽  
G. Mlynski ◽  
A.G. Beule
Keyword(s):  
Nasal Cavity ◽  
Dead Space ◽  
Homo Sapiens ◽  
Middle Turbinate ◽  
Inferior Turbinate ◽  
Point Of View ◽  
Nasal Airflow ◽  
Functional Area ◽  
External Nose ◽  
Human Nose

Background: Knowledge of airflow in animal noses is sparse. Such knowledge could be important for selection of animal models used in environmental studies. From the phylogenetic and ontogenetic point of view, a comparison between the animal and human nose is interesting. Method: Nose models of 5 even-toed ungulate species (he-goat, sheep, cow, roebuck, wild boar) and two humans (new born infant and adult) were examined. Anatomical and physiological features of the nasal cavities of all species were compared. All models were rinsed with water and the flow was visualized for observation. Geometric and rhinoresistometric measurements were then performed. Results and conclusions: Even-toed ungulates have two turbinates directly in the main part of the nasal airflow (respiratory turbinates) and a different number of turbinates in a so-called dead space of the nasal airflow above the nasopharyngeal duct (ethmoidal turbinates). The latter correspond with the upper and middle turbinate in analogy to the human nose. Respiratory turbinates of even-toed ungulates insert immediately behind the external nasal ostium. Thus, the whole nasal cavity acts as a functional area with the exception of a small area acting as dead space only detectable in ruminants, possibly indicating a small evolutionary progress from suinae to bovidae. The shape of the animal nasal cavity is stretched and flat. The airflow runs nearly completely turbulent through the nose. The nasal cavity in the adult human is relatively short and high. The area between the external nasal ostium and the head of the inferior turbinate is called inflow area. It distributes the airflow over the whole nasal cross section and generates a turbulent flow. So the airflow is prepared to contact the mucosa in the functional area (turbinate area). The morphology of the inflow area is approximately formed by the shape of the external nose. The nasal cavity of a newborn child is also stretched and flat and more similar to the nasal shape of the investigated animals. The inflow area in the newborn nose is not yet developed and corresponds with the growing external newborn nose. One can hypothesize that the inflow area in human noses is a morphological adaptation in the changed length-height-ratio of the nasal cavity.

Endoscopic and Radiologic Findings in Failed Dacryocystorhinostomy: Teaching Pearls for Success

2018 ◽  
Vol 33 (3) ◽  
pp. 247-255
Author(s):  
Islam R. Herzallah ◽  
Osama A. Marglani ◽  
Sumaiya H. Muathen ◽  
Arwa A. Obaid
Keyword(s):  
Chronic Sinusitis ◽  
Anterior Part ◽  
Care Center ◽  
Tertiary Care ◽  
Middle Turbinate ◽  
Uncinate Process ◽  
Radiologic Findings ◽  
Lacrimal Bone ◽  
Endoscopic Dcr ◽  
Failed Dacryocystorhinostomy

Background Although several studies have commented on causes of dacryocystorhinostomy (DCR) failure, detailed description of anatomical findings in such cases remains insufficient. Objective Our objective was primarily to analyze radiologic, endoscopic, and intraoperative findings in patients presenting with failed DCR and secondarily to assess the outcome of revision endoscopic DCR (endo-DCR) carried out at our institution. Methods Twenty-four failed DCRs presenting to our tertiary care center were retrospectively analyzed. Data collection included patients’ history, diagnostic, and management data, as well as thorough analysis of sinonasal CT scans, along with endoscopic and intraoperative findings. Outcome was also assessed in 21 cases with revision endo-DCR performed. Results The anterior part of uncinate process was not previously removed in 15 sides (62.5%), with unopened agger nasi in 13 sides (54.2%). The lacrimal bone was detected covering the posterior sac despite removal of the anterior ascending process of maxilla in 9 sides (37.5%). Rhinostoma was anterior to lacrimal sac in 2 sides (8.3%) and was below the sac in 7 sides (29.2%). Fibrous membrane covered the rhinostoma despite removal of all sac-overlying bones in 6 sides (25%). Other findings included intranasal adhesions, septal deviation, lateralized middle turbinate, granulation tissue, foreign body reaction, and chronic sinusitis. Nineteen of the 21 revision endo-DCRs were successful (90.5%). Conclusion This study provides a precise anatomical description of findings in cases of failed DCR. Such information is paramount in helping surgeons enhance their learning curve, refine the surgical technique, and improve patients’ outcome.

scholarly journals Pedunculated Cavernous Hemangioma Originating in the Olfactory Cleft

2014 ◽  
Vol 93 (9) ◽  
pp. E29-E33 ◽  
Author(s):  
Kaiming Su ◽  
Weitian Zhang ◽  
Haibo Shi ◽  
Shankai Yin
Keyword(s):  
Nasal Cavity ◽  
Cavernous Hemangioma ◽  
English Language ◽  
Nasal Congestion ◽  
Rare Condition ◽  
Lateral Wall ◽  
Endoscopic Examination ◽  
Nasopharyngeal Angiofibroma ◽  
Olfactory Cleft ◽  
First Case

Sinonasal cavernous hemangioma is a rare condition that usually affects the lateral wall of the nasal cavity. We report the case of a 77-year-old man who presented with severe epistaxis, nasal congestion, and olfactory dysfunction. Endoscopic examination of the nasal cavity revealed the presence of a red-blue tumor that had almost completely filled the nasopharynx. Preoperatively, it was difficult to distinguish this lesion from a juvenile nasopharyngeal angiofibroma. During endoscopic surgery, the tumor was found to originate in the left olfactory cleft, and it had a long peduncle that contained blood vessels. Postoperative histopathologic examination indicated that the mass was a cavernous hemangioma. To the best of our knowledge, this is the first case of an olfactory cleft cavernous hemangioma and the first case of olfactory cleft disease associated with a cavernous hemangioma to be reported in the English-language literature.

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