scholarly journals Sinonasal Rosai-Dorfman Disease

2014 ◽  
Vol 7 (3) ◽  
pp. 142-146
Author(s):  
Sathiya Murali ◽  
Mohan Kameswaran ◽  
Kiran Natarajan ◽  
Amarnath Devarasetty ◽  
A Senthilvadivu ◽  
...  

ABSTRACT Aim Rosai-dorfman disease (RDD) is a rare histiocytic proliferative disorder characterized by painless massive lymphadenopathy. Extranodal manifestations may occur in the head and neck area. This is a case report of a patient with sinonasal RDD and its management. Materials and methods This is a case report of a 36-year-old patient with sinonasal RDD. The clinical features, imaging and histological features are described. The patient underwent endoscopic surgery. Recurrence (8 months later) was managed by laserization of the nasal mass with KTP/532 laser followed by oral corticosteroid therapy. Results A 36-year-old lady presented with complaints of left sided nasal obstruction, nasal discharge and left facial discomfort of 6 months duration. There was history of occasional blood stained nasal discharge. Diagnostic nasal endoscopy revealed a polypoidal mass in the left nasal cavity. CT scans revealed soft tissue opacity in the left maxillary antrum, left ostiomeatal complex and extending into the left orbit. There was erosion of the posterolateral wall of the left maxilla. The patient underwent endoscopic surgery and had an uneventful postoperative recovery. Biopsy was reported as Rosai-Dorfman disease. Subsequently, 8 months later, the patient reported with a complaint of nasal obstruction and discharge. A recurrent lesion was noted in the left nasal cavity and maxillary antrum. The mass was managed by laserization followed by oral corticosteroid therapy. One year later, the patient is free from disease and has been advised regarding the necessity of periodic follow-ups. Conclusion RDD is a rare disease encountered by the otolaryngologist. The manifestation of extranodal Rosai-Dorfman disease is most commonly seen in the nasal cavity and paranasal sinuses. The clinical findings and imaging characteristics are variable and the diagnosis can be easily missed. Otolaryngologists and pathologists must be aware of the clinical presentation, imaging characteristics and histologic features of Rosai-Dorfman disease. How to cite this article Natarajan K, Devarasetty A, Murali S, Senthilvadivu A, Sudhamaheswari, Kameswaran M. Sinonasal Rosai-Dorfman Disease. Clin Rhinol An Int J 2014;7(3):142-146.

Author(s):  
K. C. Prasad ◽  
Harshitha N. ◽  
Azeem Mohiyuddin S. M. ◽  
Harshita T. R. ◽  
Indu Varsha ◽  
...  

<p class="abstract">Actinomycosis is a rare anaerobic bacterial infection that presents in the form of cervicofacial, pulmonary, thoracic and abdominopelvic infections. It is usually caused by <em>Actinomyces israelii </em>which are a part of normal flora of aerodigestive tracts. They are opportunistic pathogens and cause infections which have odontogenic origin in oral cavity. Cervicofacial actinomycosis accounts for more than half of the cases and commonly affects the mandible. We are reporting a case of actinomycosis of left maxillary antrum presenting as a nasal polypi in a young man. He had presented with nasal discharge and yellowish crusts from left nasal cavity. Diagnostic nasal endoscopy revealed yellowish polypoidal mass arising from the left middle meatus. CT PNS showed soft tissue density mass measuring 3.7×4.3×4.1 cms in left maxillary antrum extending through and obliterating osteomeatal complex extending into left ethmoidal sinus. Patient underwent Functional endoscopic sinus surgery. The yellowish polypoidal mass in left nasal cavity was attached to the floor of the maxillary antrum by a thin stalk and had filled up the antrum. Histopathology of the specimen revealed inflammatory polyp with actinomycosis. Patient had an uneventful recovery and was put on long term antibiotics and regular follow up.</p>


2005 ◽  
Vol 132 (6) ◽  
pp. 963-964 ◽  
Author(s):  
Kaoru Shinohara ◽  
Kimio Hashimoto ◽  
Masaru Yamashita ◽  
Koichi Omori

A 50-year-old woman presented with a 30-year history of nasal obstruction. She had been treated for paranasal sinusitis at other hospitals and she was referred to our hospital for further examination. Flexible endoscopy revealed a mass in the posterior aspect of the right nasal cavity to the posterior aspect of the left nasal cavity around the posterior edge of the nasal septum.


2020 ◽  
Vol 3 (1) ◽  
pp. 272-276
Author(s):  
CO Ojabo ◽  
A Adekwu ◽  
T Ben-Ameh

Rhino-orbito-cerebral mucormycosis (ROCM) is an uncommon acute aggressive fungal infection occurring in several immunocompromised states including diabetes which is the most common predisposing factor. In this case report we present the clinical finding, therapeutic challenges and outcome in a 44 years old male type II diabetic patient. Patient first presented to the ortorhinolaryngologist with complaints of nasal discharge, postnasal drip, cough, hyposmia, facial pains, and intermittent nasal obstruction. He had bilateral intranasal antrostomy, upon X-ray confirmation of homogenious opacity of the left maxillary antrum and mucosal thickening of the right antrum. Fungal study of the specimen revealed mucormycosis. Six months later he presented with perception of light (PL) vision in the right eye and non-perception of light (NPL) in the left eye. There was mild lid edema in the right eye. There was marked proptosis associated with external ophthalmoplegia suggestive of orbital apex syndrome. The conjunctiva was keratinized and the cornea necrotic and opaque. The left eye enucleation and nasal exploration were done. The patient objected to taking amphotericn B, the drug of choice for this condition because of his previous adverse reaction experience to the drug. Posacornazole, the second line drug could not be assessed, posing a great therapeutic challenge in the effective management of this case. The patient was later referred for neurosurgical management but was reported to have died at a tertiary health facility in Abuja.


DICP ◽  
1989 ◽  
Vol 23 (1) ◽  
pp. 63-63 ◽  
Author(s):  
Louise Mallet ◽  
James W. Cooper ◽  
Joyce Thomas

Captopril is commonly prescribed to patients with hypertension and congestive heart failure. Adverse dermatological reactions have been reported in about ten percent of patients receiving captopril. This case report describes a 77-year-old white woman who developed bullous pemphigoid associated with the use of captopril. The patient presented with bullous eruptions localized on the palms of both hands about 50 days after captopril 25 mg bid was started. Biopsy report was consistent with bullous pemphigoid. Captopril therapy was discontinued and the lesions healed after oral corticosteroid therapy was initiated.


2005 ◽  
Vol 13 (2) ◽  
pp. 178-180 ◽  
Author(s):  
SK Rao ◽  
BC Navadgi ◽  
A Vasdev

Spontaneous bilateral rupture of Achilles tendon is rare. Rupture of the Achilles tendon has been described in patients on oral corticosteroid therapy. The sudden dorsiflexion of the plantar-flexed foot is the usual mechanism of injury. Spontaneous bilateral rupture is common in the degenerated tendon, which is often seen in patients with long-term corticosteroid therapy. This case is unusual because the patient has never taken steroids. We discuss the mechanism of injury and other probable causes.


Author(s):  
Fathima Seles M. ◽  
Padmakantha Srinivasan ◽  
Narmadha Ramadoss

<p class="abstract">Nasal cavity schwannomas are uncommon lesions, representing less than 4% of all head and neck schwannomas. They give rise to nonspecific symptoms such as nasal obstruction, epistaxis, and anosmia. Here we report a 18year old girl who presented with nasal discharge and recurrent epistaxis for four months.</p>


2019 ◽  
Vol 9 (2) ◽  
Author(s):  
Damir Vučinić ◽  
Dag Zahirović ◽  
Dubravko Manestar ◽  
Ingrid Belac-Lovasić ◽  
Tamara Braut ◽  
...  

The aim of this report is to present a case of a patient with a recurrent nasal cavity amelanotic melanoma (AM), with emphasis on diagnosis and therapy options of this clinical entity. A 65-year-old female patient presented with pain in the right cheek region and nasal obstruction. In 2013, she was diagnosed with mucosal melanoma (MM) of the left nasal cavity. After endoscopic surgery and radiotherapy, the patient was followed by the oncology team. Five years after the initial diagnosis, rhinoscopy showed a tumorous formation in the right nasal cavity. The tumor mass was without black discoloration and was the same color as the surrounding nasal mucosa. Microscopic examination after biopsy of the tumor confirmed amelanotic MM. The patient underwent an additional endoscopic surgery. A complete standard diagnostic workup for MM found metastases in head and neck lymph nodes, on both sides. MMs of head and neck are uncommon malignancies. Unique biology of MM cells causes a high rate of recurrences. This report presents an example of recurrent AM of the nasal cavity, in treatment with checkpoint inhibitor (pembrolizumab), which could provide a good therapy option for patients with MM.


2020 ◽  
Vol 89 (5) ◽  
pp. 269-272
Author(s):  
R. Jacobs ◽  
B. Van Goethem ◽  
E. Stock ◽  
H. De Cock ◽  
T. Bosmans ◽  
...  

A six-year-old, male, castrated European shorthair cat was presented due to a lifelong history of sneezing, nasal discharge, open-mouth breathing, stertor and vestibular problems. Clinical examination showed absence of airflow through the nostrils. Computed tomography of the head revealed an infiltrative soft tissue attenuating mass in the left nasal cavity, nasopharynx and the left frontal sinus. All of these locations could be successfully accessed through ventral rhinotomy and the mass was completely removed. Histological examination identified it as an inflammatory polyp. All respiratory and neurological symptoms disappeared, and two-and-a-half years after surgery, the cat was still without complaints.


2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Ravishankar Pillenahalli Maheshwarappa ◽  
Amit Gupta ◽  
Juhi Bansal ◽  
Mahesh Virupaksha Kattimani ◽  
Sachin Shivayogappa Shabadi ◽  
...  

A 10-year-old boy presented with left-sided nasal obstruction and epistaxis. Endoscopic evaluation revealed a polypoid mass in the vestibule arising from the lateral wall of the nasal cavity anteroinferior to the left inferior turbinate. Computed tomography (CT) scan showed a soft tissue opacity in the vestibule of the left nasal cavity. After the endoscopic excision of the mass, postoperative and histopathological analyses confirmed the diagnosis of an angiofibroma.


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