scholarly journals Long-term Follow-up of Patients receiving Intraocular Pressure-lowering Medications as Cataract Surgery Candidates: A Case—control Study

2017 ◽  
Vol 11 (3) ◽  
pp. 107-112 ◽  
Author(s):  
Georgios Bontzos ◽  
Michail Agiorgiotakis ◽  
Efstathios T Detorakis
Keyword(s):  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Case Control Study ◽  
Cataract Extraction ◽  
Control Group ◽  
Pressure Lowering ◽  
Long Term Follow Up ◽  
Control Study

ABSTRACT Aim In this study, we reviewed demographics and biometric characteristics among patients receiving chronic β-blockers and prostaglandins (PGs) for primary open-angle glaucoma. We compared the age at the time of cataract surgery in different patient groups and in a control group which was not under any medication. Materials and methods Retrospective chart review of glaucomatous patients who underwent cataract extraction at the Department of Ophthalmology of the University Hospital of Heraklion, Crete, Greece, between January 1998 and December 2016 was done. Age at cataract surgery, axial length (AL), and preoperative and postoperative best-corrected visual acuities (BCVAs) were recorded. A cohort of patients without glaucoma who were operated for cataract extraction was also evaluated. Results In all, 320 patients were reviewed. There were significant results in mean age difference between the beta-antagonist and the PG group [3.05 years, 95% confidence interval (CI) 1.54-4.57] and between the beta-antagonist group with the patients receiving a combined therapy (3.02 years, 95% CI 1.14-4.91). No significant difference was found between the PG and the combination group. All the three treated groups had a significant lower mean age than the control group at the time of cataract surgery. Conclusion Based on our study, we concluded that there might be a possible association between chronic treatment with beta-antagonist agents and earlier cataract surgical time in the treated eye. Clinical significance Intraocular pressure control is often usually achieved using ophthalmic agents. Their topical and systemic effects should be monitored precisely. Earlier cataract formation might be an important side effect which the physician has to keep in mind before choosing the suitable medication. How to cite this article Bontzos G, Agiorgiotakis M, Detorakis ET. Long-term Follow-up of Patients receiving Intraocular Pressure-lowering Medications as Cataract Surgery Candidates: A Case—control Study. J Curr Glaucoma Pract 2017;11(3):107-112.

Efficacy of corticosteroid therapy in the treatment of long- lasting olfactory disorders in COVID-19 patients

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
L.A. Vaira ◽  
C. Hopkins ◽  
M. Petrocelli ◽  
J.R. Lechien ◽  
S. Cutrupi ◽  
...  
Keyword(s):  
Treatment Group ◽  
Case Control Study ◽  
Spontaneous Recovery ◽  
Olfactory Function ◽  
Control Group ◽  
Initial Control ◽  
Group A ◽  
Control Study

BACKGROUND: The growing number of COVID-19 patients with long-lasting olfactory disorders makes it necessary to identify effective treatments that enhance the spontaneous recovery of olfactory function. METHODS: Multicentre randomised case-control study that involved 18 patients with COVID-19 related anosmia or severe hyposmia for more than 30 days. Nine patients were prescribed systemic prednisone and nasal irrigation with betamethasone, ambroxol and rinazine for 15 days. The other 9, untreated, patients were used as controls. The olfactory function was evaluated with CCCRC test at 20 and 40 days from the first evaluation. RESULTS: In the control group, a median olfactory score of 20 (IQR 30) was detected at baseline. At the 20-day control there was no significant improvement in olfactory function. The improvement in olfactory performance became significant at the 40-day follow-up compared to baseline scores [60 (IQR 60) versus 20 (IQR 30)]. In the treatment group, patients had a mean olfactory score of 10 (IQR 15) at initial control. At the 20-day control, a significant im-provement in the olfactory scores, compared to the baseline, was detected [70 (IQR 40) versus 10 (IQR 15)]. Olfactory function further improved at 40 days [median score 90 (IQR 50)]. Patients in the treatment group reported significantly higher improvements of the olfactory scores than the controls at both the 20-day [40 (IQR 45) versus 10 (IQR 15)] and 40-day [60 (IQR 40) versus 30 (IQR 25)] evaluations. CONCLUSIONS: Based on the results of this study, the mix of drugs including steroids could represent a useful specific therapy to reduce the prevalence of this long-term morbidity.

scholarly journals De novo malignancies following liver transplantation: a case?control study with long-term follow-up

2006 ◽  
Vol 20 (5) ◽  
pp. 617-623 ◽  
Author(s):  
Francis Y Yao ◽  
Manjushree Gautam ◽  
Caren Palese ◽  
Raquel Rebres ◽  
Norah Terrault ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Control Study ◽  
De Novo ◽  
Case Control ◽  
Long Term Follow Up ◽  
Control Study

scholarly journals Role of assist device implantation and heart transplantation in the long-term outcome of patients with structural heart disease after catheter ablation of ventricular tachycardia

2021 ◽  
Author(s):  
Angeliki Darma ◽  
Livio Bertagnolli ◽  
Borislav Dinov ◽  
Alireza Sepehri Shamloo ◽  
Federica Torri ◽  
...  
Keyword(s):  
Case Control Study ◽  
Structural Heart Disease ◽  
Control Group ◽  
Assist Device ◽  
Matched Case ◽  
Vt Ablation ◽  
Matched Case Control Study ◽  
Control Study

Abstract Introduction Ablation of ventricular tachycardias (VTs) in patients with structural heart disease (SHD) has been associated with advanced heart failure and poor survival. Methods and results This matched case-control study sought to assess the difference in survival after left ventricular assist device (LVAD) implantation and/or heart transplantation (HTX) in SHD patients undergoing VT ablation. From the initial cohort of 309 SHD patients undergoing VT ablation (187 ischemic cardiomyopathy, mean age 64 ± 12 years, ejection fraction of 34 ± 13%), 15 patients received an LVAD and nine patients HTX after VT ablation during a follow-up period of 44 ± 33 months. Long-term survival after LVAD did not differ from the matched control group (p = 0.761), although the cause of lethal events was different. All post-HTX patients survived during follow-up. Conclusion In this matched case-control study on patients with SHD undergoing VT ablation, patients that received LVAD implantation had similar survival compared to the control group after 4‑year follow-up, while the patients with HTX had a significantly better outcome.

Intravenous Busulfan-Melphalan vs Melphalan as Preparative Regimen for Newly Diagnosed Multiple Myeloma: Long-Term Follow-Up of a Case-Control Study

2019 ◽  
Vol 19 (10) ◽  
pp. e287-e288
Author(s):  
Margarita Blanes ◽  
Jose Ignacio Lorenzo ◽  
Paz Ribas ◽  
Ana Jiménez ◽  
José David González ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Case Control Study ◽  
Case Control ◽  
Newly Diagnosed ◽  
Long Term Follow Up ◽  
Preparative Regimen ◽  
Control Study

Sleeve gastrectomy in the elderly: A case-control study with long-term follow-up of 3 years

2017 ◽  
Vol 13 (4) ◽  
pp. 575-580 ◽  
Author(s):  
Andrés Navarrete ◽  
Ricard Corcelles ◽  
Gabriel Diaz del Gobbo ◽  
Sofía Perez ◽  
Josep Vidal ◽  
...  
Keyword(s):  
Sleeve Gastrectomy ◽  
Case Control Study ◽  
The Elderly ◽  
Case Control ◽  
Long Term Follow Up ◽  
Control Study

LONG TERM FOLLOW-UP AND OUTCOME OF LIVER TRANSPLANTATION FROM HCV POSITIVE DONORS: A EUROPEAN MULTICENTRIC CASE-CONTROL STUDY

2010 ◽  
Vol 90 ◽  
pp. 169
Author(s):  
R. BALLARIN ◽  
A. CUCCHETTI ◽  
M. SPAGGIARI ◽  
R. MONTALTI ◽  
F. DI BENEDETTO ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Case Control Study ◽  
Case Control ◽  
Long Term Follow Up ◽  
Control Study

scholarly journals Long-term follow-up of intraocular pressure and pressure-lowering medication in patients following Excimer laser trabeculotomy

2020 ◽  
Author(s):  
C. Deubel ◽  
D. Böhringer ◽  
A. Anton ◽  
T. Reinhard ◽  
J. Lübke
Keyword(s):  
Intraocular Pressure ◽  
Minimally Invasive ◽  
Cataract Surgery ◽  
Excimer Laser ◽  
Invasive Procedure ◽  
Minimally Invasive Procedure ◽  
Long Term Follow Up ◽  
Excimer Laser Trabeculotomy

Abstract Background Excimer laser trabeculotomy (ELT) is a minimally invasive procedure to lower the intraocular pressure (IOP) via a photo-ablative laser that is applied to the trabecular meshwork. With this procedure, it is possible to improve the outflow of the aqueous humor. Until now, a limited number of studies examining mostly relatively small sample sizes with midterm follow-up exist. We therefore present the analysis of a large ELT cohort in a long-term follow-up. Methods We recorded data from 580 patients who underwent ELT or combined ELT with cataract surgery at our institution from November 2000 until March 2011. A total of 512 patients with primary open angle glaucoma (POAG), pseudoexfoliation glaucoma (PEX), and ocular hypertension (OHT) were included in the analysis. At every follow-up examination, the usage of IOP-lowering medication and the IOP were recorded. Failure criteria were defined as the need for another surgical glaucoma procedure, when the IOP was not 21 mmHg or less and a reduction of 20% from the baseline was not achieved with (qualified success) or without (absolute success) additional medication. Statistical analysis was done using Kaplan-Meier analysis and Cox regression. Results Four hundred twenty-eight patients underwent combined cataract and ELT surgery, and 84 underwent solitary ELT surgery. After a median follow-up time of 656 days, 87% (combined surgery) and 66% (ELT) of the patients did not have to undergo another IOP-lowering intervention; 47/31% were classified as a qualified success and 31/11% as a complete success. The IOP-lowering medication, however, could not be significantly reduced within that time period. Conclusion Especially when combined with cataract surgery, ELT is a feasible minimally invasive procedure to lower the IOP on a mid- to long-term basis. Over the long term, however, IOP-lowering medication could not be reduced.

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