Evaluation of the Efficacy of a Single Subgingival Irrigation with Ozonated Water on Gingival Inflammation, Lactate Dehydrogenase Enzyme, and Alkaline Phosphatase Enzyme Activity in GCF in the Subjects undergoing Fixed Orthodontic Appliance Therapy: A Clinical and Biochemical Study

2018 ◽  
Vol 8 (1) ◽  
pp. 33-38
Author(s):  
Ashvini M Padhye ◽  
Nrupa C Tambade
Keyword(s):  
Alkaline Phosphatase ◽  
Enzyme Activity ◽  
Lactate Dehydrogenase ◽  
Biochemical Study ◽  
Gingival Inflammation ◽  
Orthodontic Appliance ◽  
Dehydrogenase Enzyme ◽  
Fixed Orthodontic Appliance ◽  
Phosphatase Enzyme ◽  
Ozonated Water

scholarly journals Effect of Various Diluents on the Activity of Several Enzymes Present in Serum

1973 ◽  
Vol 19 (9) ◽  
pp. 1079-1080
Author(s):  
Ted W Fendley ◽  
Jane M Hochholzer ◽  
Christopher S Frings
Keyword(s):  
Alkaline Phosphatase ◽  
Creatine Kinase ◽  
Enzyme Activity ◽  
Lactate Dehydrogenase ◽  
Confidence Level ◽  
Aspartate Aminotransferase ◽  
Nacl Solution ◽  
Manual Method ◽  
Accuracy And Precision ◽  
Significant Difference

Abstract We have evaluated the effect of diluting serum with water or NaCl solution (8.5 or 9.0 g/liter) before assaying by a manual method for creatine kinase (EC 2.7.3.2), alkaline phosphatase (EC 3.1.3.1), lactate dehydrogenase (EC 1.1.1.27), and aspartate aminotransferase (EC 2.6.1.1) activity. The t test and the F test show no significant difference in the accuracy and precision of the assays at the 95% confidence level when 100 different samples were compared for each enzyme activity after use of the three diluents.

Acute Hepatopathy Associated With Mitotane Administration in a Dog

2006 ◽  
Vol 42 (4) ◽  
pp. 298-301 ◽  
Author(s):  
Craig B. Webb ◽  
David C. Twedt
Keyword(s):  
Alkaline Phosphatase ◽  
Enzyme Activity ◽  
Supportive Care ◽  
Prothrombin Time ◽  
Liver Enzyme ◽  
Hepatic Failure ◽  
Enzyme Activities ◽  
Total Bilirubin ◽  
Persistent Elevation ◽  
Phosphatase Enzyme

An adult dog with a persistent elevation in alkaline phosphatase enzyme activity was started on mitotane for suspected hyperadrenocorticism. One month later, the dog was presented for intermittent anorexia and acute icterus. The dog’s liver enzyme activities and total bilirubin were markedly elevated, prothrombin time was prolonged, and blood urea nitrogen and glucose were low. Histopathology revealed marked, centrilobular, hepatocellular loss. After discontinuation of the mitotane, the dog recovered with supportive care and was normal 3 months later, which was consistent with mitotane-associated hepatic failure.

scholarly journals Associations between Salivary Cytokines and Periodontal and Microbiological Parameters in Patients undergoing Fixed Orthodontic Appliance Treatment

2019 ◽  
Author(s):  
Yong Chen ◽  
Wong Wing Kit ◽  
Jayampath C Seneviratne ◽  
Shuying Huang ◽  
Colman McGrath ◽  
...  
Keyword(s):  
Health Status ◽  
Bacterial Load ◽  
Anaerobic Bacteria ◽  
Gingival Inflammation ◽  
Orthodontic Appliance ◽  
Orthodontic Therapy ◽  
Periodontal Inflammation ◽  
Gingival Health ◽  
Fixed Orthodontic Appliance ◽  
Aerobic And Anaerobic

Abstract Background: Orthodontic treatment can lead to microbial-induced gingival inflammation and aseptic periodontal inflammations. The aim of this study was to investigate the relationship between salivary pro-inflammatory cytokines levels with gingival health status and oral microbe loads among patients undergoing fixed orthodontic appliance treatment (FOAT). Methods: This was a cross-sectional study among a sample of 111 consecutive orthodontic patients (mean age 18.4 ± 4.4 years). Clinical examinations were conducted to assess the gingival health status employing the Modified Gingival Index (MGI), Gingival Bleeding Index (GBI) and Plaque Index (PI). Salivary microbiological assessments of total aerobic and anaerobic bacteria count, streptococci count and lactobacilli count were undertaken. Salivary immunological assessments included Interleukin-1Beta (IL-1β) and macrophage migration inhibitory factor (MIF) ELISA assays. Results: The mean ± standard deviation (SD) of salivary IL-1β was 83.52 ± 85.62 pg/ml and MIF was 4.12 ± 0.96 ng/ml. Positive significant correlations between salivary IL-1β levels and salivary bacteria counts (r=0.380~0.446, P<0.001), and between salivary MIF levels and total salivary aerobic and anaerobic bacteria counts (r=0.249~0.306, P<0.01) were observed. A significant positive correlation was found between salivary IL-1β levels and BI (r=0.216, p<0.05). Conclusions: The levels of salivary IL-1β and MIF correlate with oral bacterial load among patients undergoing fixed orthodontic therapy. This has implications in understanding gingival inflammation/ aseptic periodontal inflammation during orthodontic therapy.

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