Aprovechamiento de flora apícola en dos colmenares localizados en los cantones La Concordia y Mocache, Ecuador

Introducción. Antes de planificar actividades de manejo que permitan incrementar la producción apícola, es necesario datos de los elementos florísticos que integran los sistemas de uso de la tierra adyacentes a los colmenares, en esta ocasión para dos unidades productivas de las zonas 4 y 5 de Ecuador. Objetivos. Reconocer especies vegetales con potencial apícola, y estimar su abundancia más la durabilidad de la floración. Metodología. Con el empleo de los métodos: documental, y de campo, para el reconocimiento taxonómico de plantas melíferas, su cantidad, más el monitoreo del florecimiento de cada especie apícola. El análisis estadístico con la aplicación de la prueba de Mann Whitney a las variables abundancia y durabilidad de la floración. Resultados. Las principales familias botánicas con especies nectaríferas y poliníferas en los sitios de estudio son; Fabaceae, Anacardiaceae, Asteraceae y Capparaceae. Para el Colmenar C1 son 14 especies, pertenecientes a 12 familias, por su parte para el colmenar C2 con 22 especies, pertenecientes a 14 familias botánicas. La oferta del recurso floral tiene un comportamiento similar de abundancia de plantas entre los colmenares C1 y C2 a pesar de poseer mayor cantidad de especies con potencial apícola el colmenar C2, lo cual obedece al manejo que se aplica a las áreas que integran los diferentes sistemas de uso del suelo de cada predio. Conclusión. Finalmente, la duración de las flores de las especies que ofertan alimento a las abejas de los colmenares C1 y C2 oscila de 1 a 12 meses durante el año 2020 con predominancia para el colmenar C1 de Cordia alliodora, Erythrina edulis, Senna alata, Inga edulis, Persea americana, Hibiscus rosa-sinensis, Piper aduncum, y Cestrum racemosum que florecen entre 10 a 12 meses. En cambio, en el colmenar C2; Tridax procumbens, Pelargonium sp, y Hydrangea sp florecen durante todo el año.

Assessment of Nutraceutical Potential of Herbs for Promoting Hair Growth: Formulation Considerations of Herbal Hair Oil

Background: Hair loss is a relatively common occurrence that causes concern in people of all ages. In most cases, hair loss is permanent, but it can lead to alopecia. Hair root activation is necessary to improve hair development and prevent hair loss. Herbal cosmetics are increasingly widely used by the general public due to the concept of fewer adverse effects and a higher level of safety and security. Objective: The primary goal of this study is to prepare and evaluate herbal hair oil made from fresh components of various plants. Methods: Herbs were acquired from Pranveer Singh Institute of Technology's medicinal garden. Herbs were collected, dried, then ground in a mortar and pestle. Grinded herbs (Murraya koenigii, Hibiscus rosa-sinensis Linn., Nigella sativa, Trigonella foenum-graecum) were combined with 60% Cocos nucifera oil, heated, cooled, and filtered. Physical appearance, viscosity, pH, sensitivity test, hair growth activity, hair weight, antimicrobial test, stability test, and other criteria were determined and are reported in this text for the created herbal hair oil. Results: Herbal hair oil was odourless and reddish brown in appearance. Herbal hair oil had an appropriate refractive index, pH, saponification value, and specific gravity. After application, the herbal oil demonstrated Newtonian flow, as well as good hair growth and weight, with no irritation. Phytochemical screening showed the presence of ascorbic acid, sulphur and saponins. The formulation was found to be stable for 30 days. Conclusion: Conclusively, combination of effective herbs could be used to improve hair growth.

Effective Management of Rare Lymphangioleiomyomatosis Using Sirolimus: Tablet Matrix with Hibiscus rosa sinensis Leave Mucilage

The authors aimed to extend the discharge of Sirolimus from the tablets with a blend of herbal and synthetic polymers. In this study, Sirolimus was taken as a model drug, Hydroxy Propyl Methyl Cellulose as a synthetic polymer and mucilage from Hibiscus rosa sinensis leaves as a natural polymer. Sirolimus is an orphan drug used to treat Lymphangioleiomyomatosis damage and to suppress body refuse towards the transplanted organs. Sirolimus matrix tablets made with the blend of Hibiscus rosa sinensis leaves mucilage and Hydroxy Propyl Methyl Cellulose. The blend was assessed for flow possessions and the designed tablets were categorized for official and non-official tests including Sirolimus discharge. The Sirolimus matrix tablets possess good Sirolimus content with passible pre and post-formulation parameters. The study concludes that there were no chemical interactions between Sirolimus with polymers used. The study also revealed that Hibiscus rosa sinensis leaves mucilage can be a good polymer in grouping with other polymers for prolonged drug discharge.

Formulation and Evaluation of Gabapentin Sustained Release Matrix Tablet Using Hibiscus rosa sinensis Leaves Mucilage as Release Retardant

The major goal of this study was to develop and evaluate Sustained release matrix tablets of Gabapentin with Hibiscus rosa - sinensis leaves mucilage prepared by using wet granulation technique with microcrystalline cellulose as a diluents and magnesium stearate as a lubricant. Pre-compression and post-compression evaluation of physicochemical parameters were carried out and to be within acceptable limits. Drug and polymer compatibility were validated by FTIR measurements. Further, tablets were evaluated for in vitro release study. To get the sustained release of Gabapentin, the concentration of Hibiscus rosa- sinensis mucilage was tuned with a gas-generating agent. The % drug release of all formulation from F1 to F5 showed 91.24%, 80.24%, 70.53%, 62.12% and 49.83% respectively. All the dosage form release kinetics was computed using zero order, first order, Higuchi, and Korsmeyer–Peppas methods. From the above results, it is concluded that the n value of formulation F5 showed 0.78 suggesting anomalous (non-fickian) behavior of the drug. Mucilage from the leaves of Hibiscus rosa-sinensis has a great retarding effect in drug release from sustained release tablets.

KARAKTERISTIK BIOMASSA DAUN BUNGA SEPATU MENJADI BAHAN BAKAR STERNO GEL

Sterno gel daun bunga sepatu (Hibiscus rosa-sinensis L.) merupakan sumber energi alternatif yang dapat digunakan sebagai bahan bakar dikarenakan mempunyai karakteristik tidak mudah menguap, selama proses pembakaran tidak berasap, tidak berjelaga serta tidak menghasilkan emisi gas yang berbahaya dan karsinogenik serta tidak mempunyai dampak emisi terhadap lingkungan, Di dalam daun bunga sepatu terdapat kandungan saponin, β-sitosterol, stigmasterol, tarakseril asetat dan 3-siklopropan dan turunannya yang akan larut baik dalam air maupun etanol dan akan membentuk koloidal dalam air. Dengan komposisi tersebut peneliti memanfaatkan biomassa daun bunga sepatu menjadi bahan bakar sterno gel, dimana pada penelitian ini variablenya adalah filtrat massa daun bunga sepatu :10,1 20, 30, 40,50,60 dan 70 gram dan massa karbopol :1, 1.5, 2 dan 2.5 gram. Dari penelitian didapatkan waktu pembakaran terbaik pada 60 gram massa filtrat bunga sepatu dan massa karbopol 2.5 gram yaitu 25,02 menit dengan nilai emisi gas yang dihasilkan NOx : 4 ppm, SO2 : 3 ppm dan H2S : 2 ppm. Sedangkan nilai kalornya adalah 3500 kalori.

A BUCOLIC REMEDY OF FORMULATION AND EVALUATION OF POLYHERBAL HAIR OIL

Objective: The birth of cosmetics forms an incessant narrative throughout the past of man as they developed. The present study aimed to formulate polyherbal hair oil using various efficient herbs. Methods: Hair oil formulation of Cocos nucifera (oil), Ricinus communis (oil), Brassica juncea (oil), Trigonella foenum-graecum (Seeds), Murraya koenigii (Leaf), Hibiscus rosa-sinensis (Flowers), Nigella sativa (seeds), and Cinnamomum camphora in the form of polyherbal oil using boiling method. These ingredients are rich in various phytochemicals, vitamins, proteins, antioxidants, and so many other constituents which are important for the growth and rejuvenation of the hair cycle. Evaluation of hair oil carries out by various parameters such as sensitivity test, acid value, saponification value, phytochemical screening, pH, specific gravity, viscosity, and irritation test. Results: All the values of evaluation are within the acceptable limit. As compared to market formulations, this herbal oil having minimal or zero adverse effects. Conclusion: It is concluded that formulated hair oil boost hair growth, decrease hair fall, dandruff, gray hair, and gives lustrous and shiny hairs.

In Silico Studies of Bioactive Compounds from Hibiscus rosa-sinensis Against HER2 and ESR1 for Breast Cancer Treatment

The most common type of cancer and the second biggest cause of death is breast cancer. The disease is the leading cause of death in women aged 45 to 55. It's a multi-stage disease in which viruses have a role in one stage. Breast cancer is an illness that affects the sufferer, their family, and the entire community all over the world. Breast cancer has no established cause, however specific risk factors have been found. Age, race, gender, and family history are all fixed and immutable characteristics. Other elements, such as social and familial support, can help to mitigate the harmful effects.The aim of the present study was to investigate the bioactive ligand for the breast cancer treatment against the HER2 and ESR1 proteins by molecular docking studies. HER2 is an oncogene and membrane tyrosine kinase that is overexpressed and gene amplified in about 20% of breast tumours. When active, it sends proliferative and anti-apoptotic signals to the cell. It is the most important factor in the genesis and progression of breast cancer tumours. To carry out this work protein structures were download from the PDB database and ligands three dimensional structures were downloaded from the PubChem database. The docking was performed by using the iGEMDOCK software suit. The binding energies of bioactive molecules from Hibiscus rosa-sinensis were found to be Rutin (-139.779, -102.743), Quercetin (-106.5, -99.7807), Kaempferol (-105.824, -92.5271), Myricetin (-111.913, -99.603) and Methotrexate (-140.69, -130.165) against HER2 and ESR1 proteins respectively. Lowest energy of Rutin compared to Methotrexate showed highest binding among the other bioactive molecules.The binding energies of the molecules are the sum of hydrogen bond, vanderwaal’s and electrostatic energies that inversely linked to protein-ligand interaction. From the result of the current study we can conclude that among the four bioactive molecule rutin has lowest binding energy so it could be used as an inhibitor of HER2 and ESR1 protein for the treatment of breast carcinoma in future.

Jatropha integerrima, Duranta erecta and Hibiscus rosa-sinensis as Potential Lead Absorbent from Polluted Air in Dense Traffic Area

Lead (Pb) is one of the contaminants found in polluted air, especially in the area with dense traffic. Herbaceous plants are potentially used to reduce the Pb content in the polluted air. This study was designed to evaluate the potential of several plants, such as Jatropha integerrima, Duranta erecta and Hibiscus rosa-sinensis, as Pb absorbents from polluted air based on Pb accumulation and chlorophyll levels. The lead content was measured using atomic absorption spectrophotometry (AAS), while the chlorophyll content was tested using spectrophotometers at wavelengths of 649 nm and 665 nm. Results showed that the three plant species had potential as Pb absorbents from the air. The highest lead content was found from J. integerrima at 1.293 mg/kg, followed by H. rosa-sinensis at 1.232 mg/kg and D. erecta at 0.840 mg/kg. On the other hand, the highest level of leaf chlorophyll content was H. rosa-sinensis at 16.116 mg/kg, followed by D. erecta L. at 12.594 mg/kg and J. integerrima Jacq. of 10.297 mg/kg. No correlation was found between the Pb level and chlorophyll content of the three plants. It can be concluded that the three herbaceous plants have potential as Pb absorbents in the polluted air.