scholarly journals Bacterial Etiology of Otitis Media and their Antibiotic Susceptibility Pattern among Patients coming to a Tertiary Care Hospital, Jaipur, India

Author(s):  
Mohit Agrawal ◽  
Gunjan Pandey

ABSTRACT Aim The aim of the study was to identify the microorganisms associated with the chronic discharging ears and their antimicrobial susceptibility pattern. Materials and methods A total of 251 samples of ear swabs were received at Mahatma Gandhi Medical College & Hospital, Jaipur, Rajasthan, India. Pus samples were taken from external auditory canal using sterile cotton swabs and then cultured on different microbiological media. Antibiotic sensitivity was tested and interpreted by method according to Clinical and Laboratory Standards Institute standards. Results Out of 251 samples received, 135 (53.78%) samples had growth. The microbiology of these 135 samples was studied. Pseudomonas aeruginosa was the major organism isolated from 88 samples followed by Staphylococcus aureus (37), and other coliforms (10). Drug susceptibility of P. aeruginosa showed that colistin was active against all isolates followed by piperacillin-tazobactam and imipenem. Approximately 60% S. aureus isolates were methicillin-resistant S. aureus. Vancomycin, linezolid, and teicoplanin were 100% sensitive. Conclusion From the current study, it was concluded that P. aeruginosa is the potential cause of ear-associated infections. All isolates of P. aeruginosa were susceptible to colistin, and S. aureus was susceptible to vancomycin, linezolid, and teicoplanin. How to cite this article Agrawal M, Gupta N, Pandey G. Bacterial Etiology of Otitis Media and their Antibiotic Susceptibi­lity Pattern among Patients coming to a Tertiary Care Hospital, Jaipur, India. J Mahatma Gandhi Univ Med Sci Tech 2017;2(1):7-9.

Author(s):  
R. K. Mahajan ◽  
Saumya Agarwal ◽  
Hishmi Jeram ◽  
R. C. Vashishtha

Background: Chronic suppurative otitis media (CSOM) is a massive public health problem in developing countries like India, especially among low socio-economic class because of malnutrition, overcrowding, poor hygiene, inadequate health care and recurrent upper respiratory tract infections. CSOM cases unless managed effectively may land into various complications such as persistent otorrhoea, hearing impairment, mastoiditis, labyrinthitis, facial nerve paralysis to more serious intracranial abscesses.Methods: The study was carried out in a tertiary care hospital from January 2017 to December 2017 with an aim to determine the microbiological profile of ear discharge in patients suffering from CSOM and their antimicrobial susceptibility pattern using Kirby Bauer disc diffusion method.Results: Out of 630 samples processed, 407 (64.6%) samples were culture positive. Most common organism isolated was Pseudomonas spp. (43.2%) followed by S. aureus (39.1%). Most of isolates recovered were multidrug resistant.Conclusions: Management of CSOM consists mainly of eradicating infection and closure of tympanic membrane. Periodic monitoring of bacterial isolates and their antibiotic susceptibility pattern is necessary for administering appropriate antibiotics as empirical treatment and also helps in reducing the potentially disabling and fatal complications of CSOM.


Author(s):  
Vijayashree V. ◽  
Saikeerthana D. ◽  
Prabha P.

Background: The genus Klebsiella of Enterobacteriaceae family is ubiquitous in nature. They cause many nosocomial infections like pneumonia, urinary tract infections, wound infections, bacteremia and septicemia. Multidrug resistance is seen in Klebsiella which serves as the most common cause of increased morbidity and mortality. This study reveals the prevalence and antibiotic sensitivity pattern of Klebsiella species from various clinical samples. The primary objectives are as follows: To isolate and characterize Klebsiella species from various clinical samples. To study the antibiotic susceptibility pattern of Klebsiella isolates.Methods: This prospective study was conducted in our tertiary care hospital during the period from August 2019 to October 2019. A total of 3521 samples were tested during this period. The samples include blood, sputum, urine, and pus.Results: Out of the total samples tested,1106 samples were showing the growth of the organisms. Among this,351 were identified as Klebsiella species and the highest rate of isolation of Klebsiella species is from the sputum sample and also the same was reported high in medical wards. The study also shows that the isolation of Klebsiella species shows male preponderance when compared to females. The antibiotic sensitivity pattern was done by Kirby-Bauer's disc diffusion method and the sensitivity was noted to be higher to amikacin and ciprofloxacin.Conclusions: Thus, this study shows the prevalence rate of Klebsiella species and sensitivity pattern of Klebsiella, which may help select appropriate antibiotics and prevent overuse and misuse of antibiotics.


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